Correlation of fluid pressure and microdroplet size in a 3D-printed microfluidic chip
Abstract
This paper reports the droplet formation performance of a 3D-printed microfluidic chip according to fluid pressure. SLA (stereolithography) 3D printer was employed for manufacturing the transparent microfluidic chip from resin. Water in oil microdroplets was produced on a flow-focusing design. Oil and water inlets were driven by a constant pressure source. The droplet production performance of the microfluidic chip was monitored through a microscope. The size of water droplets was determined according to pressure values.
Keywords
Microfluidic, microdroplet, 3D-printing
Project Number
2021/043
References
- Bhargava, Krisna C, Bryant Thompson, and Noah Malmstadt (2014) Discrete elements for 3D microfluidics. Proceedings of the National Academy of Sciences 111(42):15013-15018.
- Bilican, İsmail, and Mustafa Tahsin Guler (2020) Assessment of PMMA and polystyrene-based microfluidic chips fabricated using CO2 laser machining. Applied Surface Science 534:147642.
- Donvito, Lidia, et al. (2015) Experimental validation of a simple, low-cost, T-junction droplet generator fabricated through 3D printing. Journal of Micromechanics and Microengineering 25(3):035013.
- Ghorbanpoor, Hamed, et al. (2022) A fully integrated rapid on-chip antibiotic susceptibility test–A case study for Mycobacterium smegmatis. Sensors and Actuators A: Physical 339:113515.
- Guler, M Tahsin (2022) Fabricating plasma bonded microfluidic chips by CO2 laser machining of PDMS by the application of viscoelastic particle focusing and droplet generation. Journal of Manufacturing Processes 73:260-268.
- Guler, Mustafa Tahsin, Murat Inal, and Ismail Bilican (2021) CO2 laser machining for microfluidics mold fabrication from PMMA with applications on viscoelastic focusing, electrospun nanofiber production, and droplet generation. Journal of Industrial and Engineering Chemistry 98:340-349.
- Isiksacan, Ziya, et al. (2016) Rapid fabrication of microfluidic PDMS devices from reusable PDMS molds using laser ablation. Journal of Micromechanics and Microengineering 26(3):035008.
- Kecili, Seren, and H Cumhur Tekin (2020) Adhesive bonding strategies to fabricate the high-strength and transparent 3D printed microfluidic device. Biomicrofluidics 14(2):024113.
- Kim, Tyson N, et al. (2005) Femtosecond laser-drilled capillary integrated into a microfluidic device. Applied Physics Letters 86(20):201106.
- Kotz, Frederik, et al. (2018) Highly fluorinated methacrylates for optical 3D printing of microfluidic devices. Micromachines 9(3):115.