Obez Kedilerde Sol Ventrikül Hipertrofisinin Ekokardiyografik Bulguları

Öz

Bu çalışmanın temel amacı, sağlıklı kedilerde obezitenin sol ventrikül hipertrofisi oluşumunu nasıl etkilediğini değerlendirmektir. Araştırmacılar, çalışmayı gerçekleştirmeden önce tüm katılımcı kedilerin vücut kondisyon skorunu değerlendirdiler. Ayrıca, transtorasik 2D, M-mode ve Doppler dahil çeşitli ekokardiyografik muayeneler ve sistolik kan basıncı ölçümleri gerçekleştirdiler. Sonuçlar, obez ve obez olmayan gruplar arasında vücut kondisyon skorları arasında önemli bir farklılık olduğunu gösterdi (P < .001). Ayrıca, 2 grup arasında sistolik kan basıncı (SKB) ve kalp hızı açısından önemli farklar gözlendi (P < .001, P = .002). Ekokardiyografik ölçümler, obez ve obez olmayan kediler arasında sol atriyum ve sol ventrikül serbest duvar kalınlığı arasında istatistiksel olarak anlamlı farklılıklar ortaya koydu (P < .001 ve P = .003). Obeziteyi ele almak için obez grupa, ekokardiyografik parametrelerde ve SKB’de iyileşmelere yol açan düşük kalorili bir diyet uyguladı. Ancak, bu iyileştirmeler istatistiksel bir anlamlılığa ulaşmadı. Çalışma bulguları, obezitenin kedi popülasyonunda sol ventrikül hipertrofisine neden olabilecek önemli miyokard değişikliklerine yol açabileceğini gösteriyor, ki bu daha önce insanlarda ve köpeklerde rapor edilmiştir. Ayrıca, çalışma, bir diyet müdahalesinin obez kedilerde hipertrofik kardiyomiyopati gibi hastalıkları önlemeye yardımcı olabileceğini öne sürmektedir.

Anahtar Kelimeler

• Ekokardiyografi
• kan basıncı
• kardiyomiyopati
• obezite
• kedi

Echocardiographic Evidence of Left Ventricular Hypertrophy in Obese Cats

Öz

The primary objective of this study was to assess how obesity impacts the occurrence of left ventricular hypertrophy in healthy cats. The researchers evaluated the body condition score of all participating cats before conducting the study. Additionally, they performed various echocardiographic examinations, including transthoracic 2D, M-mode, and Doppler, as well as measuring systolic blood pressure. The results indicated a notable distinction in body condition scores between the non-obese and obese groups (P < .001). Moreover, significant differences were observed in terms of systolic blood pressure (SBP) and heart rate between the 2 groups (P < .001, P = .002). Echocardiographic measurements revealed statistically significant variations in left atrium and left ventricular free wall thickness between non-obese and obese cats (P < .001 and P = .003). To address obesity, the obese group underwent a lowcalorie diet, leading to improvements in echocardiographic parameters and SBP. However, these improvements did not achieve statistical significance. The study findings indicate that obesity can lead to substantial myocardial changes, resulting in left ventricular hypertrophy in cats, which has been previously reported in humans and dogs. Additionally, the study suggests that a diet intervention for obese cats might help prevent diseases like hypertrophic cardiomyopathy.

Anahtar Kelimeler

• Echocardiography
• blood pressure
• cardiomyopathy
• obesity
• cat

Kaynakça

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