CNT Supported Bimetallic Ru-Mo Catalyst for the Detection of L-Histidine

Yıl 2024, Cilt: 2 Sayı: 2, 22 - 30, 20.12.2024

Ömrüye Özok Arıcı , Hilal Demir Kıvrak , Aykut Çağlar , Arif Kıvrak

Öz

In this study, a voltammetric L-Histidine (His) sensor is being developed with glassy carbon electrode (GCE) modified with carbon nanotube (CNT) supported Ru-Mo bimetallic catalyst. The Ru-Mo/CNT catalyst was prepared by sodium borohydride reduction method. It was identified by surface analytical methods like scanning electron microscopy (SEM) and X-ray diffraction (XRD).
Characterization results reveal that this catalyst was successfully synthesized. The modified GCE's electrochemical activity was investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS).
The Ru-Mo/CNT-modified GCE electrode has a sensitivity of 0.0002 mA/cm2, a limit of detection (LOD) of 0.02 µM for histidine, and a lower limit of detection (LOQ) of 0.06 µM, according to electrochemical data. The findings demonstrate that the Ru-Mo/CNT-modified GCE electrode is a promising catalyst for the sensitive detection of L-histidine and has been manufactured for the first time in the literature.

Anahtar Kelimeler

amino acid, histidine, sensor

L-Histidinin tespiti için CNT Destekli Bimetalik Ru-Mo Katalizörü

Öz

Bu çalışmada, karbon nanotüp (CNT) destekli Ru-Mo bimetalik katalizörle modifiye edilmiş camsı karbon elektrot (GCE) ile bir voltametrik L-Histidin (His) sensörü geliştirilmektedir.Ru-Mo/CNT, katalizörü, sodyum borohidrit indirgeme yöntemiyle hazırlandı. X-ışını kırınımı (XRD) ve taramalı elektron mikroskobu (SEM) gibi yüzey analitik teknikleri ile karakterize edildi. Karakterizasyon sonuçları bu katalizörün başarıyla sentezlendiğini ortaya koymaktadır. Karakterizasyon sonuçları bu katalizörün başarıyla sentezlendiğini ortaya koymaktadır. Modifiye edilmiş GCE'nin elektrokimyasal davranışını incelemek için elektrokimyasal empedans spektroskopisi (EIS), diferansiyel darbe voltametrisi (DPV) ve döngüsel voltametri (CV) kullanılmıştır. Elektrokimyasal sonuçlar, Ru-Mo/CNT ile modifiye edilmiş GCE elektrotunun 0.0002 mA/cm2 duyarlılığına, histidin için tespit limiti (LOD) 0.02 µM ve alt tayin sınırına (LOQ) 0.06 µM'ye sahip olduğunu göstermektedir. Sonuç olarak, sonuçlar Ru-Mo/CNT ile modifiye edilmiş GCE elektrotunun literatürde ilk kez sentezlendiğini ve L-histidinin hassas tespiti için umut verici bir katalizör olduğunu göstermektedir.

Anahtar Kelimeler

amino asit, histidin, sensör

Kaynakça

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