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2020 Yılına Damgasını Vuran Pandemi: COVID-19'a (SARSCoV-2) Genel Bir Bakış

Yıl 2021, Cilt: 2 Sayı: 2, 18 - 31, 30.04.2021

Öz

Coronavirus hastalığı 2019 (COVID-19), SARS-CoV-2 olarak
isimlendirilen yeni koronavirüsün etken olduğu, Çin’den
yayılan ve tüm dünyada dikkatleri üzerine çeken bir enfeksiyon
hastalığıdır. COVID-19 tüm dünya genelinde neredeyse 219
ülkeye hızla yayılarak pandemi özelliği edinmiştir. Yarasalar
rezervuar olarak tanımlanmaktadır ve olası ara konaklar hala
araştırılmaktadır. Virus asemptomatik enfeksiyonlardan, şiddetli
pnömoni, akut solunum yetmezliği sendromu, sitokin fırtınası
ve ölümle sonuçlanan letal tablo ile ilişkilidir. Hastalığın ölümcül
şeklinin yaşlılık, immün yetersizlik ve kronik hastalıkların varlığı
ile ilişkili olduğu rapor edilmiştir. Şu ana değin COVID-19’a karşı
klinik olarak onaylanmış özel bir ilaç yoktur ve onaylı aşılara
ulaşım da sınırlı düzeydedir. Bu derlemede SARS-CoV-2’nin
genel özellikleri, sınıflandırılması, epidemiyolojisi, patogenezi,
tanı ve tedavi yöntemleri ile virusa karşı korunma stratejilerine
ilişkin bilgiler verilmiştir.

Kaynakça

  • 1. Harapan H, Itoh N, Yufika A, Winardi W, Keam S, Te H. et al. Coronavirus disease 2019 (COVID-19): A literature review. J Infect Public Health. 2020; 13(5):667-673.
  • 2. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H. et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet. 2020;395(10224):565-574.
  • 3. Sun J, He WT, Wang L, Lai A, Ji X, Zhai X. et al. COVID-19: Epidemiology, evolution, and cross-disciplinary perspectives. Trends in Molecular Medicine. 2020;26(5):483-495
  • 4. https://www.who.int/csr/sars/country/table2004_04_21/en/
  • 5. Gorbalenya AE, Baker SC, Baric R, Groot RJD, Drosten C, Gulyaeva AA. et al. Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology. 2020;5:536–544.
  • 6. Ge H, Wang X, Yuan X, Xiao G, Wang C, Deng T. et al. The epidemiology and clinical information about COVID-19. Eur J Clin Microbiol Infect Dis. 2020; 14:1–9.
  • 7. Yi Y, Lagniton PN, Ye S, Li E, Xu RH. COVID-19: what has been learned and to be learned about the novel coronavirus disease. Int J Biol Sci. 2020;16(10):1753.
  • 8. Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A, Osborne M, Li VY. et al. Diagnosing COVID-19: the disease and tools for detection. ACS Nano. 2020;14(4):3822-35.
  • 9. Kannan S, Ali PSS, Sheeza A, Hemalatha K. COVID-19 (Novel Coronavirus 2019)-recent trends. Eur Rev Med Pharmacol Sci. 2020;24(4):2006-11.
  • 10. Baloch S, Baloch MA, Zheng T, Pei X. The Coronavirus Disease 2019 (COVID-19) Pandemic. The Tohoku J Exper Med. 2020; 250(4):271-278.
  • 11. Jiang F, Deng L, Zhang L, Cai Y, Cheung CW. et al. Review of the clinical characteristics of coronavirus disease 2019 (COVID-19). J General Int Med. 2020;1-5.
  • 12. Fiorillo L, Cervino G, Matarese M, D’Amico C, Surace G, Paduano V. et al. COVID-19 Surface Persistence: A Recent Data Summary and Its Importance for Medical and Dental Settings. Int J Environment Res Public Health. 2020;17(9):3132.
  • 13. Jin Y, Yang H, Ji W, Wu W, Chen S, Zhang, W, Duan G. Virology, epidemiology, pathogenesis, and control of COVID-19. Viruses. 2020;12(4):372.
  • 14. Guo YR, Cao QD, Hong ZS, Tan YY, Chen SD, Jin HJ. et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Med Res. 2020;7(1):1-10.
  • 15. Hamid S, Mir MY, Rohela GK. Noval coronavirus disease (COVID-19): A pandemic (Epidemiology, Pathogenesis and potential therapeutics). New Microb New Infect. 2020;100679.
  • 16. Ji W, Wang W, Zhao X, Zai J, Li X. Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human. J Med Virol. 2020; 92(4):1-31.
  • 17. Xiao KP, Zhai JQ, Feng YY, Zhou N, Zhang X, Zou JJ, et al. Isolation and characterization of 2019-nCoV-like coronavirus from Malayan Pangolins. BioRxiv. 2020.
  • 18. Tang X, Wu C, Li X, Song Y, Yao X, Wu X. et al. On the origin and continuing evolution of SARS-CoV-2. National Science Review. 2020;3:1-26.
  • 19. Ahn DG, Shin HJ, Kim MH, Lee S, Kim HS, Myoung, J. et al. Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19). J Microbiol Biotec. 2020;30(3):313-324.
  • 20. Mousavizadeh L, Ghasemi S. Genotype and phenotype of COVID-19: Their roles in pathogenesis. J Microbiol Immun Infect. 2020 (in press).
  • 21. Millet JK, Whittaker GR. Host cell proteases: critical determinants of coronavirus tropism and pathogenesis. Virus Res. 2015;202:120–34.
  • 22. Simmons G, Gosalia DN, Rennekamp AJ, Reeves JD, Diamond SL, Bates P. Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. P Natl Acad Sci USA. 2005;102(33):11876–81.
  • 23. Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. 2020; 13;367(6483):1260-63.
  • 24. Khodadadi E, Maroufi P, Khodadadi E, Esposito I, Ganbarov K, Espsoito S. et al. Study of combining virtual screening and antiviral treatments of the Sars-CoV-2 (Covid-19). Microbial Pathogenesis. 2020;146:104241.
  • 25. Kang S, Yang M, Hong Z, Zhang L, Huang Z, Chen X. et al. Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites. Acta Pharmaceutica Sinica B. 2020; 10(7):1228-1238.
  • 26. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506.
  • 27. Chen J, Qi T, Liu L, Ling Y, Qian Z, Li T et al. Clinical progression of patients with COVID-19 in Shanghai, China. Journal of Infection. 2020;80(5):1–6.
  • 28. Gralinski LE, Menachery VD. Return of the Coronavirus: 2019-nCoV. Viruses. 2020;12(2): 135.
  • 29. Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. Journal of Travel Medicine. 2020; 13;27(2):21.
  • 30. Yang X, Yu Y, Xu J, Shu H, Liu H, Wu Y. et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020;8:475-481.
  • 31. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C. et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. New England Journal of Medicine. 2020;382(10):970-971.
  • 32. Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. Journal of Pharmaceutical Analysis. 2020; 10(2):102–108.
  • 33. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX. et al. Clinical characteristics of coronavirus disease 2019 in China. New England J Med. 2020; 382(18):1708-1720. 34. https://en.huanqiu.com/
  • 35. Uddin M, Mustafa F, Rizvi TA, Loney T, Suwaidi HA, Al-Marzouqi AHH. et al. SARS-CoV-2/COVID-19: Viral genomics, epidemiology, vaccines, and therapeutic interventions. Viruses. 2020; 12(5):526.
  • 36. Sanche S, Lin YT, Xu C, Romero-Severson E, Hengartner N, Ke R. Early Release-High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2. 2020;26(7):1470-1477
  • 37. Shi J, Wen Z, Zhong G, Yang H, Wang C, Huang B. et al. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2. Science. 2020;368(6494): 1016-1020.
  • 38. Sobral MFF, Duarte GB, da Penha Sobral AIG, Marinho MLM, de Souza Melo A. Association between climate variables and global transmission oF SARS-CoV-2. Science of The Total Environment. 2020;729:138997.
  • 39. Rabaan AA, Al-Ahmed SH, Haque S, Sah R, Tiwari R, Malik YS. et al. SARS-CoV-2, SARS-CoV, and MERS-CoV: a comparative overview. Infez Med. 2020;28(2):174-184.
  • 40. Rabi FA, Al Zoubi MS, Kasasbeh GA, Salameh DM, Al-Nasser AD. SARS-CoV-2 and coronavirus disease 2019: what we know so far. Pathogens. 2020;9(3):231.
  • 41. Xia S, Yan L, Xu W, Agrawal AS, Algaissi A, Tseng CTK. et al. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science advances. 2019;5(4):4580.
  • 42. Dhama K, Patel SK, Pathak M, Yatoo MI, Tiwari R, Malik YS. et al. An update on SARS-CoV-2/COVID-19 with particular reference to its clinical pathology, pathogenesis, immunopathology and mitigation strategies. Travel Medicine and Infectious Disease. 2020; 101755.
  • 43. Carter LJ, Garner LV, Smoot JW, Li Y, Zhou Q, Saveson C J. et al. Assay techniques and test development for COVID-19 diagnosis. ACS Cent Sci. 2020;6(5):591–605.
  • 44. Zumla A, Hui DS, Perlman S. Middle East respiratory syndrome. Lancet. 2015;386:995–1007.
  • 45. Ozma MA, Maroufi P, Khodadadi E, Köse Ş, Esposito I, Ganbarov K. et al. Clinical manifestation, diagnosis, prevention and control of SARS-CoV-2 (COVID-19) during the outbreak period. Infez Med.2020;28(2):153-65.
  • 46. https://www.gisaid.org/epiflu-applications/next-hcov-19-app/
  • 47. Hou T, Zeng W, Yang M, Chen W, Ren L, Ai J et al. Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19. PLoS Pathogens. 2020;16(8):e1008705.
  • 48. Zhang W, Du RH, Li B, Zheng XS, Yang XL, Hu B. et al. Molecular and Serological Investigation of 2019-nCoV Infected Patients: Implication of Multiple Shedding Routes. Emerging Microbes Infect. 2020;9(1):386−389.
  • 49. Patel R, Babady E, Theel ES, Storch GA, Pinsky BA, George KS. et al. Report from the American Society for Microbiology COVID-19 international summit, 23 march 2020: value of diagnostic testing for SARS–CoV-2/COVID-19. 2020;11(2):1-5
  • 50. Dong Y, Dai T, Wei Y, Zhang L, Zheng M, Zhou F. A systematic review of SARS-CoV-2 vaccine candidates. Signal Trans Target Therapy. 2020;5(1):1-14.
  • 51. Mirzaei R, Mohammadzadeh R, Mahdavi F, Badrzadeh F, Kazemi S, Ebrahimi M. et al. Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. International immunopharmacology. 2020; 106928.
  • 52. Du L, He Y, Zhou Y, Liu S, Zheng BJ, Jiang S. The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol. 2009;7:226-236.
  • 53. Li F. Structure, function, and evolution of coronavirus spike proteins. Annu Rev Virol. 2016;3:237-261.
  • 54. Clover Biopharmaceuticals vaccines programs. Available from http://www.cloverbiopharma.com/index.php?m=content&c=index&a=lists&catid=42.
  • 55. Fathizadeh H, Maroufi P, Momen-Heravi M, Dao S, Köse Ş, Ganbarov K. et al. Protection and disinfection policies against SARS-CoV-2 (COVID-19). Infez Med. 2020; 28(2):185-91.
  • 56. Self WH., Semler MW, Leither LM, Casey JD, Angus DC, Brower RG. et al. Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19: a randomized clinical trial. JAMA. 2020;324(21):2165-76.
  • 57. Li L, Zhang W, Hu Y, Tong X, Zheng S, Yang J. et al. Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial. JAMA. 2020;324(5):460-470.
Toplam 56 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Birinci Basamak Sağlık Hizmetleri
Bölüm Derlemeler
Yazarlar

Fatma Kalaycı Yüksek 0000-0002-0028-5646

Defne Gümüş 0000-0003-4070-6924

Yayımlanma Tarihi 30 Nisan 2021
Gönderilme Tarihi 8 Şubat 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 2 Sayı: 2

Kaynak Göster

AMA Kalaycı Yüksek F, Gümüş D. 2020 Yılına Damgasını Vuran Pandemi: COVID-19’a (SARSCoV-2) Genel Bir Bakış. JMS. Nisan 2021;2(2):18-31.