Araştırma Makalesi
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The Relationship Between Macronutrients, Anthropometric Measurements and Biochemical Parameters of Adolescents with Metabolic Syndrome

Yıl 2025, Cilt: 6 Sayı: 3, 282 - 291, 04.12.2025

Öz

Giriş: Adölesanlarda obezite sıklığının artması ile birlikte ülkemizde metabolik sendrom prevelansında artış görülmektedir.
Amaç: Metabolik sendrom tanısı almış adölesanların beslenme durumlarını, antropometrik ölçümlerini ve biyokimyasal parametrelerini sağlıklı yaşıtları ike karşılaştırmaktır.
Yöntemler: Çalışmaya İstanbul ilinde yaşayan 14-18 yaş arası 40 metabolik sendromlu ve 40 sağlıklı adölesan dahil edildi. Demografik bilgileri içeren bir anket formu uygulandı. Vücut ağırlığı, boy uzunluğu, bel çevresi ölçüldü ve beslenme durumlarını belirlemek için araştırmacı tarafından geriye dönük 24 saatlik besin tüketim kaydı alındı. Hastane kayıtlarından, metabolik sendromla ilişkili glukoz, insülin, trigliserit, total kolesterol, HDL kolesterol, AST, ALT, kan basıncı değerleri kaydedildi.
Bulgular: Metabolik sendromlu adölesanlarda vücut ağırlığı, BKİ, bel çevresi ölçümleri ve glukoz, insülin, trigliserit, total ve HDL kolesterol, AST, ALT gibi biyokimyasal parametreler sağlıklı yaşıtlarına göre daha yüksek bulunmuştur (p<0.01). Besin tüketim kayıtları incelendiğinde metabolik sendromlu adölesanların karbonhidrat (%), lif (g) alımları sağlıklı yaşıtlarına göre daha yüksek, yağ (%) düşüktür (p<0.01). Yağ (g) alımı ile antropometrik ölçümlerden VKİ, biyokimyasal parametrelerden glukoz arasında pozitif korelasyon bulunmuştur (p<0.05). Toplam enerjinin karbonhidrattan gelen oranı arttıkça ALT, AST düzeyleri artmaktadır (p<0.05).
Sonuç: Metabolik sendromlu ergenlerin sağlıklı akranlarına kıyasla daha fazla miktarda enerji, karbonhidrat ve lif tükettiği, fakat daha yeterli ve dengeli bir günlük diyete sahip oldukları bulundu. Bu bulgular, özellikle daha genç yaş grupları için erken müdahale stratejilerinin önemini vurgulamaktadır.

Etik Beyan

The study was approved by Bezmialem Vakıf University Scientific Research Ethics Committee (7130642-050.01.04-). A voluntary consent form was obtained from the families of the patients who agreed to participate in the study.

Kaynakça

  • 1. Arslan M, Atmaca A, Ayvaz G et al. Türkiye Endokrinoloji ve Metabolizma Derneği. Ankara, 2009;7-8.
  • 2. Noubiap JJ, Nansseu JR, Lontchi-Yimagou E, Nkeck JR, Nyaga UF, Ngouo AT et al. Global, regional, and country estimates of metabolic syndrome burden in children and adolescents in 2020: a systematic review and modelling analysis. Lancet Child Adolesc Health 2022; 6(3): 158-170.
  • 3. Aycan Z. Cocukluk cağında obezite ve metabolik sendrom. Turk J Pediatr 2016; 10: XI- XII.
  • 4. Güven S, Aktepe U, Yazar AS, Erdem A, Karakayalı B, Başat S. The prevalence of metabolic syndrome among obese and overweight children according to the different criteria. Haydarpaşa Numune Med J 2015; 55: 170-80.
  • 5. Sangun O, Dundar B, Kosker M, Pirgon O, Dundar N. Prevalence of metabolic syndrome in obese children and adolescents using three different criteria and evaluation of risk factors. J Clin Res Ped Endocrinol 2011 doi: 10.4274/jcrpe.v3i2.15.
  • 6. Keser A, Yucecan S, Cizmecioglu FM, Etiler N, Hatun S. The relationship between risk factors o f metabolic syndrome in childhood and nutrition patterns. J Nutr and Diet 2008; 36: 9-22.
  • 7. Ozer S, Sonmezgoz E, Unuvar S, Yılmaz R, Demir O. Evaluation of frequency of metabolic syndrome and its components in obese Children. J Child 2015 doi: 10.5222/j.child.2015.010.
  • 8. Araslı Yılmaz A, Ozaydın E, Demirel F, Kose G. A retrospective evaluation of the factors contributing to obesity and the existence of metabolic syndrome in adolescents. Turk J Pediatr 2015 doi: 10.12956/tjpd.2015.185.
  • 9. van de Laar RJJ, Stehouwer CDA, van Bussel BCT, Prins MH, Twisk JWR, Ferreira I. Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood: the Amsterdam Growth and Health Longitudinal Study. J Intern Med 2012 doi: 10.1111/j.1365-2796.2012.02577.x.
  • 10. Mendoza JA, Liu Y. Active commuting to elementary school and adiposity: an observational study. Child Obes 2014 doi: 10.1089/chi.2013.0133.
  • 11. Casadei K, Kiel J, Anthropometric Measurement. Treasure Island, FL, USA: StatPears Publishing, 2020.
  • 12. World Health Organization. (2024, June 3). Growth reference data for 5–19 years. World Health Organization. https://www.who.int/tools/growth-referencedata-for-5to19-years
  • 13.Ozturk A, Borlu A, Cicek B, Altunay C, Unalan D, Horoz D, Balcı E, Ustunbas HB, Bayat M, Mazıcıoglu MM, Hatipoglu N, Kurtoglu S, Kesim S. Growth charts for 0-18 year old children and adolescentsTurkish. TJFMPC 2011doi: 10.2399/tahd.11.112.
  • 14. Ryder JR, Jacobs DR, Sinaiko AR, Kornblum AP, Steinberger J. Longitudinal changes in weight status from childhood and adolescence to adulthood. J Pediatr 2019 doi: 10.1016/j.jpeds.2019.07.035.
  • 15. Bebispro for Windows, Stuttgart, Germany; Turkish Version (Bebis 4), Istanbul, 2004. Program uses data from Bundeslebensmittelschlüssel (BLS) 11.3 and USDA 15.
  • 16. Türkiye Beslenme Rehberi (TÜBER)-2022. T.C. Sağlık Bakanlığı Yayın No: 1031, Ankara 2022. Access Date: 16.04.2024 https://hsgm.saglik.gov.tr/depo/birimler/saglikli-beslenme-ve-hareketli-hayat-db/Dokumanlar/Rehberler/Turkiye_Beslenme_Rehber_TUBER_2022_min.pdf
  • 17. American National Academy of Sciences, Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids. National Academy Press, Washington DC, 2002.
  • 18.Garipagaoglu M, Budak N, Oner N, Saglam O, Nisli K. The evaluation of nutritional status and body weights of female university students attending three different universities. J. Health Sci. 2006; 15: 173-81.
  • 19. Papadaki A, Linardakis M, Codrington C, Kafatos A. Nutritional intake of children and adolescents with insulin-dependent diabetes mellitus in crete, Greece. Ann Nutr Metab 2008 doi: 10.1159/000151484.
  • 20. Turney, S. (2024). Pearson Correlation Coefficient (r) | Guide & Examples. Scribbr. Erişim adresi: https://www.scribbr.com/statistics/pearson-correlation-coefficient/
  • 21.Nogay NH, Koksal G. Nutritional management of metabolic syndrome in children. J Pediatr Res 2012 doi: 10.4274/Jcp.10.04
  • 22. Park SI, Suh J, Lee HS, Song K, Choi Y, Oh JS et al. Ten-year trends of metabolic syndrome prevalence and nutrient intake among Korean children and adolescents: a population-based study. Yonsei Med J 2021; 62 (4): 344.
  • 23. Larruy-García A, Mahmood L, Miguel-Berges ML, Masip G, Seral-Cortés M, De Miguel-Etayo P et al. Diet Quality scores, obesity and metabolic syndrome in children and adolescents: a systematic review and meta-analysis. Current obesity reports, 2024; 13(4): 755-788.
  • 24.Ramírez-López G, Flores-Aldana M, Salmerón J. Associations between dietary patterns and metabolic syndrome in adolescents. Salud Publica Mex 2019 doi: 10.21149/9541.
  • 25. Elizondo-Montemayor L, Serrano-González M, Ugalde-Casas PA, Cuello-Garciá C, Borbolla-Escoboza JR. Metabolic syndrome risk factors among a sample of overweight and obese Mexican children. J Clin Hypertens (Greenwich) 2010 doi: 10.1111/j.1751-7176.2010.00263.x.

Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki

Yıl 2025, Cilt: 6 Sayı: 3, 282 - 291, 04.12.2025

Öz

Background: With the increasing prevalence of obesity in adolescents, the prevalence of metabolic syndrome is increasing in our country.
Objective: To compare the nutritional status, anthropometric measurements and biochemical parameters of adolescents diagnosed with metabolic syndrome with their healthy peers.
Methods: The study included 40 adolescents with metabolic syndrome, 40 healthy adolescents aged 14-18 years living in Istanbul. A questionnaire including demographic information was applied. Body weight, height, and waist circumference were measured and a retrospective 24-hour dietary recal was taken by the researcher to determine their nutritional status. Glucose, insulin, triglyceride, total cholesterol, HDL cholesterol, AST, ALT, blood pressure values associated with metabolic syndrome were recorded from hospital records.
Results: Body weight, BMI, waist circumference measurements and biochemical parameters including glucose, insulin, triglycerides, total and HDL cholesterol, AST, ALT were found to be higher in adolescents with metabolic syndrome compared to their healthy peers (p<0.01). When food consumption records were examined, carbohydrate (%) and fiber (g) intakes of adolescents with metabolic syndrome were higher and fat (%) was lower (p<0.01). Positive correlation was found between fat (g) intake and BMI among anthropometric measurements and glucose among biochemical parameters (p<0.05). ALT and AST levels increased as the proportion of total energy coming from carbohydrate increased (p<0.05).
Conclusion: Adolescents with metabolic syndrome were found to consume higher amounts of energy, carbohydrates and fiber, but had a more adequate and balanced daily diet compared to their healthy peers. These findings emphasize the importance of early intervention strategies, especially for younger age groups.

Etik Beyan

The study was approved by Bezmialem Vakıf University Scientific Research Ethics Committee (7130642-050.01.04-). A voluntary consent form was obtained from the families of the patients who agreed to participate in the study.

Kaynakça

  • 1. Arslan M, Atmaca A, Ayvaz G et al. Türkiye Endokrinoloji ve Metabolizma Derneği. Ankara, 2009;7-8.
  • 2. Noubiap JJ, Nansseu JR, Lontchi-Yimagou E, Nkeck JR, Nyaga UF, Ngouo AT et al. Global, regional, and country estimates of metabolic syndrome burden in children and adolescents in 2020: a systematic review and modelling analysis. Lancet Child Adolesc Health 2022; 6(3): 158-170.
  • 3. Aycan Z. Cocukluk cağında obezite ve metabolik sendrom. Turk J Pediatr 2016; 10: XI- XII.
  • 4. Güven S, Aktepe U, Yazar AS, Erdem A, Karakayalı B, Başat S. The prevalence of metabolic syndrome among obese and overweight children according to the different criteria. Haydarpaşa Numune Med J 2015; 55: 170-80.
  • 5. Sangun O, Dundar B, Kosker M, Pirgon O, Dundar N. Prevalence of metabolic syndrome in obese children and adolescents using three different criteria and evaluation of risk factors. J Clin Res Ped Endocrinol 2011 doi: 10.4274/jcrpe.v3i2.15.
  • 6. Keser A, Yucecan S, Cizmecioglu FM, Etiler N, Hatun S. The relationship between risk factors o f metabolic syndrome in childhood and nutrition patterns. J Nutr and Diet 2008; 36: 9-22.
  • 7. Ozer S, Sonmezgoz E, Unuvar S, Yılmaz R, Demir O. Evaluation of frequency of metabolic syndrome and its components in obese Children. J Child 2015 doi: 10.5222/j.child.2015.010.
  • 8. Araslı Yılmaz A, Ozaydın E, Demirel F, Kose G. A retrospective evaluation of the factors contributing to obesity and the existence of metabolic syndrome in adolescents. Turk J Pediatr 2015 doi: 10.12956/tjpd.2015.185.
  • 9. van de Laar RJJ, Stehouwer CDA, van Bussel BCT, Prins MH, Twisk JWR, Ferreira I. Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood: the Amsterdam Growth and Health Longitudinal Study. J Intern Med 2012 doi: 10.1111/j.1365-2796.2012.02577.x.
  • 10. Mendoza JA, Liu Y. Active commuting to elementary school and adiposity: an observational study. Child Obes 2014 doi: 10.1089/chi.2013.0133.
  • 11. Casadei K, Kiel J, Anthropometric Measurement. Treasure Island, FL, USA: StatPears Publishing, 2020.
  • 12. World Health Organization. (2024, June 3). Growth reference data for 5–19 years. World Health Organization. https://www.who.int/tools/growth-referencedata-for-5to19-years
  • 13.Ozturk A, Borlu A, Cicek B, Altunay C, Unalan D, Horoz D, Balcı E, Ustunbas HB, Bayat M, Mazıcıoglu MM, Hatipoglu N, Kurtoglu S, Kesim S. Growth charts for 0-18 year old children and adolescentsTurkish. TJFMPC 2011doi: 10.2399/tahd.11.112.
  • 14. Ryder JR, Jacobs DR, Sinaiko AR, Kornblum AP, Steinberger J. Longitudinal changes in weight status from childhood and adolescence to adulthood. J Pediatr 2019 doi: 10.1016/j.jpeds.2019.07.035.
  • 15. Bebispro for Windows, Stuttgart, Germany; Turkish Version (Bebis 4), Istanbul, 2004. Program uses data from Bundeslebensmittelschlüssel (BLS) 11.3 and USDA 15.
  • 16. Türkiye Beslenme Rehberi (TÜBER)-2022. T.C. Sağlık Bakanlığı Yayın No: 1031, Ankara 2022. Access Date: 16.04.2024 https://hsgm.saglik.gov.tr/depo/birimler/saglikli-beslenme-ve-hareketli-hayat-db/Dokumanlar/Rehberler/Turkiye_Beslenme_Rehber_TUBER_2022_min.pdf
  • 17. American National Academy of Sciences, Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids. National Academy Press, Washington DC, 2002.
  • 18.Garipagaoglu M, Budak N, Oner N, Saglam O, Nisli K. The evaluation of nutritional status and body weights of female university students attending three different universities. J. Health Sci. 2006; 15: 173-81.
  • 19. Papadaki A, Linardakis M, Codrington C, Kafatos A. Nutritional intake of children and adolescents with insulin-dependent diabetes mellitus in crete, Greece. Ann Nutr Metab 2008 doi: 10.1159/000151484.
  • 20. Turney, S. (2024). Pearson Correlation Coefficient (r) | Guide & Examples. Scribbr. Erişim adresi: https://www.scribbr.com/statistics/pearson-correlation-coefficient/
  • 21.Nogay NH, Koksal G. Nutritional management of metabolic syndrome in children. J Pediatr Res 2012 doi: 10.4274/Jcp.10.04
  • 22. Park SI, Suh J, Lee HS, Song K, Choi Y, Oh JS et al. Ten-year trends of metabolic syndrome prevalence and nutrient intake among Korean children and adolescents: a population-based study. Yonsei Med J 2021; 62 (4): 344.
  • 23. Larruy-García A, Mahmood L, Miguel-Berges ML, Masip G, Seral-Cortés M, De Miguel-Etayo P et al. Diet Quality scores, obesity and metabolic syndrome in children and adolescents: a systematic review and meta-analysis. Current obesity reports, 2024; 13(4): 755-788.
  • 24.Ramírez-López G, Flores-Aldana M, Salmerón J. Associations between dietary patterns and metabolic syndrome in adolescents. Salud Publica Mex 2019 doi: 10.21149/9541.
  • 25. Elizondo-Montemayor L, Serrano-González M, Ugalde-Casas PA, Cuello-Garciá C, Borbolla-Escoboza JR. Metabolic syndrome risk factors among a sample of overweight and obese Mexican children. J Clin Hypertens (Greenwich) 2010 doi: 10.1111/j.1751-7176.2010.00263.x.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Sağlığı ve Hastalıkları Hemşireliği
Bölüm Araştırma Makalesi
Yazarlar

Eftal Geçgil Demir 0000-0001-7154-7714

Muazzez Garipağaoğlu 0000-0003-2172-1467

Gönderilme Tarihi 5 Mart 2025
Kabul Tarihi 11 Eylül 2025
Yayımlanma Tarihi 4 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 6 Sayı: 3

Kaynak Göster

APA Geçgil Demir, E., & Garipağaoğlu, M. (2025). Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki. YOBÜ Sağlık Bilimleri Fakültesi Dergisi, 6(3), 282-291.
AMA Geçgil Demir E, Garipağaoğlu M. Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki. YOBÜ Sağlık Bilimleri Fakültesi Dergisi. Aralık 2025;6(3):282-291.
Chicago Geçgil Demir, Eftal, ve Muazzez Garipağaoğlu. “Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki”. YOBÜ Sağlık Bilimleri Fakültesi Dergisi 6, sy. 3 (Aralık 2025): 282-91.
EndNote Geçgil Demir E, Garipağaoğlu M (01 Aralık 2025) Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki. YOBÜ Sağlık Bilimleri Fakültesi Dergisi 6 3 282–291.
IEEE E. Geçgil Demir ve M. Garipağaoğlu, “Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki”, YOBÜ Sağlık Bilimleri Fakültesi Dergisi, c. 6, sy. 3, ss. 282–291, 2025.
ISNAD Geçgil Demir, Eftal - Garipağaoğlu, Muazzez. “Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki”. YOBÜ Sağlık Bilimleri Fakültesi Dergisi 6/3 (Aralık2025), 282-291.
JAMA Geçgil Demir E, Garipağaoğlu M. Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki. YOBÜ Sağlık Bilimleri Fakültesi Dergisi. 2025;6:282–291.
MLA Geçgil Demir, Eftal ve Muazzez Garipağaoğlu. “Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki”. YOBÜ Sağlık Bilimleri Fakültesi Dergisi, c. 6, sy. 3, 2025, ss. 282-91.
Vancouver Geçgil Demir E, Garipağaoğlu M. Metabolik Sendromlu Ergenlerde Makro Besin Öğeleri, Antropometrik Ölçümler ve Biyokimyasal Parametreler Arasındaki İlişki. YOBÜ Sağlık Bilimleri Fakültesi Dergisi. 2025;6(3):282-91.