Gebe keçilerde serum adenozin deaminaz aktiviteleri üzerine bir çalışma

Yıl 2000, Cilt: 6 Sayı: 1-2 - 2000, 42 - 45, 18.06.2000

Muhammet Alan Zahit Tevfık Ağaoğlu Nuri Altuğ Ahmet Uyar İbrahim Taşal

Öz

Bu çalışmada keçilerde gebeliğin çeşitli dönemlerinde ve doğumdan sonra serum adenozin deaminaz aktivitelerinin araştırılması amaçlanmıştır. Materyal olarak 9 adet Siirt Keçisi kullanıldı. Keçilerden aşım sonrası 21., 40., 75., 100. ve 145. günlerde ve doğumdan 10 gün sonra kan alınarak serumları çıkartıldı. Serumlar aynı gün Yüzüncü Yıl Üniversitesi merkez laboratuvarında işlenerek adenozin deaminaz aktiviteleri IU/L cinsinden belirlendi. Keçilerde doğum sonrasında daha yüksek elde edilen adenozin deaminaz aktivitesi gebelik dönemi ilerledikçe düşmüş ve doğuma en yakın zamanda en düşük aktivite elde edilmiştir. Yukarıdaki kan alma günlerinde sırasıyla elde edilen aktiviteler 5.6, 4.59, 3.96, 2.52, 1.54 ve 7.15 IU/L olmuştur. Doğum sonu ile gebeliğin 21., 40. 100. ve 145. günlerinde elde edilen adenozin deaminaz aktiviteleri istatistiki yönden de farklı çıkmıştır P< 0.001 . Sonuç olarak, keçilerde gebelik döneminde serum adenozin deaminaz aktivitesinin önemli derecede düştüğü, bu düşüşün aşım sonrası 21. günden itibaren belirlenebileceği ve gebelik tanısında yararlı olabileceği ve gebeliğin ilerlemesine parelel olarak adenozin deaminaz düşüşlerinin sağlıklı bir gebeliğe işaret edebileceği kanısına varılmıştır

Anahtar Kelimeler

Keçi, Gebelik, Adenozin deaminaz

A study on serum adeııosine deamiııase activities in pregnant goats

Öz

The activities of adenosine deaminase in different periods of pregnaney and after parturition were investigated in 9 goats. Blood samples weıe collected at days 21, 40, 75, 100, 145 of pregnaney and at day 10 after parturition. Serums were harvested from these samples and adenosine deaminase levels were assayed as IU/L. Adenosine deaminase activity was higher after parturition but lowed during pregnaney. The lowest activity was assayed nearest the term. Activities at the sampling times were 5.6, 4.59, 3.96, 2.52, 1.54 and 7.15 IU/L, respeetively. Adenosine deaminase activities were different at days 21, 40, 100, 145 and after parturition P< 0.001 . It was concluded that serum adenosine deaminase activities low importantly during pregnaney towards to term. Low level can be predieted as early as at day 21. This condition of this enzyme may be useful at pregnaney diagnosis and may be indicate normal pregnancies

Anahtar Kelimeler

Goat, Pregnaney, Adenosine deaminase.

Kaynakça

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