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POLİSİTEMİ

Yıl 2006, Cilt: 9 Sayı: 2, 33 - 39, 01.06.2006

Öz

Polisitemi eritrositozis , eritrosit sayısı, hematokrit değer ve hemoglobin konsantrasyonunda artışla karekterize olan patolojik bir durumdur Polisitemi, absolut ve relatif polisitemi olarak; absolut polisitemi de primer polisitemia rubra vera ve sekunder uygun, uygunsuz olarak ikiye ayrılmaktadır. Eritropoietin seviyesi polisitemilerin ayırıcı teşhislerinde klinik olarak çok önemlidir. Eritropoietin seviyesi P. vera'da düşük, sekunder eritrositoziste yüksektir. Sekunder polisitemili hastalarda çoğunlukla idrar veya plazma ya da her ikisinde de Eritropoietin konsantrasyonu artmıştır. Bu derlemede, polisitemilerin sınıflandırılması, teşhis yöntemleri ve tedavi olanakları hakkında bilgiler verilerek, karşılaşılan şüpheli vakaların detaylı incelenmesinde yardımcı olabilecek bilgileri aktarmak amaçlanmıştır

Kaynakça

  • 1- Giger U: Erythropoietin and its Clinical Use, Comp. ContinuingEducationArticle, 14(1),25-34, (1992).
  • 2- Jain NC: In:Essential of veterinary hematology, LeaFebiger, Philadelphia, (1993).
  • 3- Golde DW, Hocking WG, Koeffler HP, Adamson JW: Polycythemia: Mechanisms and Management. Ann. Inter. Med., 95,71-87, (1981).
  • 4- Gilbert HS: Definition, clinical features and diagnosis of the poltcythemia States. Ann. Clin. Lab. Sci. 10:311- 319,(1975).
  • 5- Peterson ME, Randolf JF: Diagnosis of canine primary polycythemia and management with hydroxyurea. J. Am. Vet. Med. Assoc. 180 (4): 415-418, (1982).
  • 6- Wintrobe MM: Clinical Hematology. Philadelphia:LeaFebiger, 690, (1981).
  • 7- Graber SE, Krantz SB: Erythropoietin: Biology and clinical use. Hematol Oncol Clin North Am, 3:369, (1989).
  • 8- DiBartola SP, Rutgers HC, Zack PM, Tarr MJ: Clinicopathologic findings assosiated with cronic renal disease in cats: 74 cases JAWMA 190: 1196-1202, (1987).
  • 9- Campbell KL: Diagnosis and management of polycythemia in dogs. Compend. Contin. Educ. Pract. Vet.l2(4):543-550, (1990).
  • 10- Koeffler MP, Goldwasser E: Erythropoietin radioimmunoassay in evaluating in polycythemia. Ann. Intem. Med. 94:44-47,(1981).
  • 11- Birgegard G et al: Serum erythropoietin levels by radioimmunoassay in polycythemia. Scand. J. Heamatol. 29:161 -165, (1982).
  • 12- Foster ES and Lothrop CD: Polycythemia vera in a cat with cardiac hypertrophy. J. Am. Vet. Med. Assoc. 192:1736,(1988).
  • 13- Walker BR, Resta TC, Nelin LD: Nitric oxide-dependent pulmonary vasodilation in polycythemic rats. Am J PhysiolHeart Circ Physiol, 297(5): H2382-9, (2000).
  • 14- Frisbee JC, Murrant CL, Wilson BA, Barklay JK: Polycythemia decreases fatigue in tetanic constractions of skeletal muscle. Med Sci Sports Exerc, 31(9): 1293- 1298,(1999).
  • 15- Wagner KF, Katschinski DM, Hasegawa J, Schumacher D, Meller B, Gembruch U, Schramm U, Jelkmann W, Gassmann M, Fandrey J: Chronic inborn erythrocytosis leads to cardiac dysfunction and prematüre death in mice overexpressmg erythropoietin. Blood, 97(2):536- 542„(2001).
  • 16- Erslev AJ and Caro J: Pathophysiology and classifıcation of polycythaemia. Scand. J. Haematol., 31, 287-292, (1983).
  • 17- Heimpel H: The present State of pathophysiology and therapeutic trials in polycythemia vera. Int. J Hematol, 64(3-4):153-165,(1996).
  • 18- Peterson ME and Randolf JF: Diagnosis and treatment of polycythemia. In: Kirk RW, ed. Current veterinary teraphy VIII. Philadelphia: WB Saunders Co, 406-408, (1983).
  • 19- Bunn HF: Erythropoietin: Current Status, The Yale Journal of Biology andMedicine, 63,381-386, (1990).
  • 20 Erslev AJ: Erythropoietin, The New England Journal of Medicine, 324 (19), 1339-1344, (1991).
  • 21- Popovic WJ, Adamson JW: Erythropoietin assay: present status of methods, pitfalls, and results in polycythemic disorders. CRC Crit. Rev. Clin. Lab. Sci. 10: 57-87, (1979).
  • 22- Rosenthal A, Marsh S, Manor D, et al: DNA synthesis by erythroid precursors in a completely defined medium: a rapid, sensitive, and convenient bioassay for erythropoietin. Exp. Hematol. 13:174-184,(1985).
  • 23- Jacobson LO, Goldwasser E, Fried W, Plzak L. Role of the kidney inerythropoiesis.Nature. 179:633-634,(1957).
  • 24- Thorling EB: Paraneoplastic erythrocytosis and inappropriate erythropoietin production: a review. Scaııd. J.Haematol. 17(Suppl. 17): 1-166,(1972).
  • 25- Adamson JW: Familial polycythemia. Semin. Hematol. 12:383-396,(1975).
  • 26- Greenberg BR, Golde DW: Eıythropoiesis in familial erythrocytosis. N. Engl. J. Med. 296: 1080-1084, (1972).
  • 27- Abildgaard CF, Comet J, Schulman I: Prymary erythrocytosis. J. Pediatr. 63:1072-1080, (1973).
  • 28- Berlin NI: Diagnosis and classifîcation of the polycthemia States. Semin. Hematol. 12:339-351, (1975).
  • 29- Brodsky I: The differential diagnosis of the polycythemia States. Ann. Clin. Lab. Sci. 10:311-319, (1980).
  • 30- Couto CG, Boudrieau RJ and Zanjani ED: Tumorassociated erythrocytosis in a dog with nasal fibrosarcoma. J. Vet. Int. Med., 3,183-185, (1989).
  • 31- Peterson ME, Zanjani ED: inappropriate erythropoietin production from a renal carcinoma in a dog with polycythemia. J. Am. Vet. Med. Assoc. 179: 995-996, (1981).
  • 32- Görse MJ: Polycythemia associated with renal fibrosarcomain a dog. J. Am. Vet. Med. Assoc. 192:793, (1988).
  • 33- Harvey JW: Myeloproliferative disorders in dogs and cats. Vet. Clin. North. Am. (Small Anim. Pract.) 11:349- 381,(1981).
  • 34- Petrites-Murphy MB, Kenneth R. Pierce, Fisher JW: Effect of incorporation of serum from dogs with renal impairment on canine erythroid bone marrow cultures. Am. J. Vet. Res. 50 (9); 153 7-1543,(1989).
  • 35- Eschbach JW, Kelly MR, Haley NR et al: Treatment of anemia of Progressive renal failure with recombinant human erythropoietin N. Eng. J. Med. 321:158-163, (1989).
  • 36- Nelson RW, Hager D, Zanjani ED: Renal lymphosarcoma with inappropriate erythropoietin production in a dog. JAVMA, 182:1396-1397, (1983).
  • 37- Codner EC: Transient Erythrocytosis (Primary Polycytaemia) in a Dog. Com. Haematol. Int, 2, 111- 113,(1992).
  • 38- Lennox TJ, Wilson JH, Ilayden DW, Bouljihad M, Sage AM, Walser MM, Manivel JC: Hepatoblastoma with erythrocytosis in a young female horse. J Am Vet Med Assoc, 216(5):718-721, (2000).
  • 39- Turgut K: Veteriner klinik laboratuvar teşhis. 2. baskı, Bölüm 2; 17-78, Bahçıvanlar basım sanayi A.Ş, (2000).
  • 40- Kirk RW, Bistner Sİ, Ford RB: Handbook of Veterinary Procedures and Emergency Treatmenr., 5th Ed., 664- 665, WB Sauııders Company, (1990).
  • 41- Caro J and Erslev AJ: Erythropoietin assays and their use in the study of anemias. Contrib. Nephrol. 66:54, (1988).
  • 42- Dunn CDR, Lange RD: Erythropoietin: assay and characterization; in Roaths, Topical reviews in hematology, pp: 1-32 (Wright, Bristol), (1979).
  • 43- Chandler EA, Thompson DJ, Sutton JB, Price CJ: Canine medicine and therapetics, 3rd Ed., Chapter 11:417-448; Chapter 23:771 -808. Blackwell Science, (1995).
  • 44- Hoffman R and Wasserman LR: Natura! history and management of polycythemia vera. Adv. Intem. Med., 24:255-285,(1979).
  • 45- Barragry TB: Veterinary Drug Therapy Chapter 36: 919- 940. Lea-Febıger, USA, (1994).

POLYCYTHEMİA

Yıl 2006, Cilt: 9 Sayı: 2, 33 - 39, 01.06.2006

Öz

Polycythemia erythrocytsis is a State characterizid by an elevated erythrocyte mass, hematocrit value and hemoglobin concentration. Polycythemia may be relative or absolute. Absolute polycythemia can be primary polycythemia rubra vera or secondary appropriate or inappropriate . Erythropoietin level is very important for differential diagnosis of polycythemia. Erythropoietin level is decreased in polycythemia vera and elevated in seconder erythrocytosis. Erythropoietin concentration is elevated in urine or plasma or either in patient with seconder polycythemia. In this review, it has been given some information about the classifıcation, diagnosis and treatment of polycythemia. It is aimed to give some Information that could heplful in detailed examination of suspected cases

Kaynakça

  • 1- Giger U: Erythropoietin and its Clinical Use, Comp. ContinuingEducationArticle, 14(1),25-34, (1992).
  • 2- Jain NC: In:Essential of veterinary hematology, LeaFebiger, Philadelphia, (1993).
  • 3- Golde DW, Hocking WG, Koeffler HP, Adamson JW: Polycythemia: Mechanisms and Management. Ann. Inter. Med., 95,71-87, (1981).
  • 4- Gilbert HS: Definition, clinical features and diagnosis of the poltcythemia States. Ann. Clin. Lab. Sci. 10:311- 319,(1975).
  • 5- Peterson ME, Randolf JF: Diagnosis of canine primary polycythemia and management with hydroxyurea. J. Am. Vet. Med. Assoc. 180 (4): 415-418, (1982).
  • 6- Wintrobe MM: Clinical Hematology. Philadelphia:LeaFebiger, 690, (1981).
  • 7- Graber SE, Krantz SB: Erythropoietin: Biology and clinical use. Hematol Oncol Clin North Am, 3:369, (1989).
  • 8- DiBartola SP, Rutgers HC, Zack PM, Tarr MJ: Clinicopathologic findings assosiated with cronic renal disease in cats: 74 cases JAWMA 190: 1196-1202, (1987).
  • 9- Campbell KL: Diagnosis and management of polycythemia in dogs. Compend. Contin. Educ. Pract. Vet.l2(4):543-550, (1990).
  • 10- Koeffler MP, Goldwasser E: Erythropoietin radioimmunoassay in evaluating in polycythemia. Ann. Intem. Med. 94:44-47,(1981).
  • 11- Birgegard G et al: Serum erythropoietin levels by radioimmunoassay in polycythemia. Scand. J. Heamatol. 29:161 -165, (1982).
  • 12- Foster ES and Lothrop CD: Polycythemia vera in a cat with cardiac hypertrophy. J. Am. Vet. Med. Assoc. 192:1736,(1988).
  • 13- Walker BR, Resta TC, Nelin LD: Nitric oxide-dependent pulmonary vasodilation in polycythemic rats. Am J PhysiolHeart Circ Physiol, 297(5): H2382-9, (2000).
  • 14- Frisbee JC, Murrant CL, Wilson BA, Barklay JK: Polycythemia decreases fatigue in tetanic constractions of skeletal muscle. Med Sci Sports Exerc, 31(9): 1293- 1298,(1999).
  • 15- Wagner KF, Katschinski DM, Hasegawa J, Schumacher D, Meller B, Gembruch U, Schramm U, Jelkmann W, Gassmann M, Fandrey J: Chronic inborn erythrocytosis leads to cardiac dysfunction and prematüre death in mice overexpressmg erythropoietin. Blood, 97(2):536- 542„(2001).
  • 16- Erslev AJ and Caro J: Pathophysiology and classifıcation of polycythaemia. Scand. J. Haematol., 31, 287-292, (1983).
  • 17- Heimpel H: The present State of pathophysiology and therapeutic trials in polycythemia vera. Int. J Hematol, 64(3-4):153-165,(1996).
  • 18- Peterson ME and Randolf JF: Diagnosis and treatment of polycythemia. In: Kirk RW, ed. Current veterinary teraphy VIII. Philadelphia: WB Saunders Co, 406-408, (1983).
  • 19- Bunn HF: Erythropoietin: Current Status, The Yale Journal of Biology andMedicine, 63,381-386, (1990).
  • 20 Erslev AJ: Erythropoietin, The New England Journal of Medicine, 324 (19), 1339-1344, (1991).
  • 21- Popovic WJ, Adamson JW: Erythropoietin assay: present status of methods, pitfalls, and results in polycythemic disorders. CRC Crit. Rev. Clin. Lab. Sci. 10: 57-87, (1979).
  • 22- Rosenthal A, Marsh S, Manor D, et al: DNA synthesis by erythroid precursors in a completely defined medium: a rapid, sensitive, and convenient bioassay for erythropoietin. Exp. Hematol. 13:174-184,(1985).
  • 23- Jacobson LO, Goldwasser E, Fried W, Plzak L. Role of the kidney inerythropoiesis.Nature. 179:633-634,(1957).
  • 24- Thorling EB: Paraneoplastic erythrocytosis and inappropriate erythropoietin production: a review. Scaııd. J.Haematol. 17(Suppl. 17): 1-166,(1972).
  • 25- Adamson JW: Familial polycythemia. Semin. Hematol. 12:383-396,(1975).
  • 26- Greenberg BR, Golde DW: Eıythropoiesis in familial erythrocytosis. N. Engl. J. Med. 296: 1080-1084, (1972).
  • 27- Abildgaard CF, Comet J, Schulman I: Prymary erythrocytosis. J. Pediatr. 63:1072-1080, (1973).
  • 28- Berlin NI: Diagnosis and classifîcation of the polycthemia States. Semin. Hematol. 12:339-351, (1975).
  • 29- Brodsky I: The differential diagnosis of the polycythemia States. Ann. Clin. Lab. Sci. 10:311-319, (1980).
  • 30- Couto CG, Boudrieau RJ and Zanjani ED: Tumorassociated erythrocytosis in a dog with nasal fibrosarcoma. J. Vet. Int. Med., 3,183-185, (1989).
  • 31- Peterson ME, Zanjani ED: inappropriate erythropoietin production from a renal carcinoma in a dog with polycythemia. J. Am. Vet. Med. Assoc. 179: 995-996, (1981).
  • 32- Görse MJ: Polycythemia associated with renal fibrosarcomain a dog. J. Am. Vet. Med. Assoc. 192:793, (1988).
  • 33- Harvey JW: Myeloproliferative disorders in dogs and cats. Vet. Clin. North. Am. (Small Anim. Pract.) 11:349- 381,(1981).
  • 34- Petrites-Murphy MB, Kenneth R. Pierce, Fisher JW: Effect of incorporation of serum from dogs with renal impairment on canine erythroid bone marrow cultures. Am. J. Vet. Res. 50 (9); 153 7-1543,(1989).
  • 35- Eschbach JW, Kelly MR, Haley NR et al: Treatment of anemia of Progressive renal failure with recombinant human erythropoietin N. Eng. J. Med. 321:158-163, (1989).
  • 36- Nelson RW, Hager D, Zanjani ED: Renal lymphosarcoma with inappropriate erythropoietin production in a dog. JAVMA, 182:1396-1397, (1983).
  • 37- Codner EC: Transient Erythrocytosis (Primary Polycytaemia) in a Dog. Com. Haematol. Int, 2, 111- 113,(1992).
  • 38- Lennox TJ, Wilson JH, Ilayden DW, Bouljihad M, Sage AM, Walser MM, Manivel JC: Hepatoblastoma with erythrocytosis in a young female horse. J Am Vet Med Assoc, 216(5):718-721, (2000).
  • 39- Turgut K: Veteriner klinik laboratuvar teşhis. 2. baskı, Bölüm 2; 17-78, Bahçıvanlar basım sanayi A.Ş, (2000).
  • 40- Kirk RW, Bistner Sİ, Ford RB: Handbook of Veterinary Procedures and Emergency Treatmenr., 5th Ed., 664- 665, WB Sauııders Company, (1990).
  • 41- Caro J and Erslev AJ: Erythropoietin assays and their use in the study of anemias. Contrib. Nephrol. 66:54, (1988).
  • 42- Dunn CDR, Lange RD: Erythropoietin: assay and characterization; in Roaths, Topical reviews in hematology, pp: 1-32 (Wright, Bristol), (1979).
  • 43- Chandler EA, Thompson DJ, Sutton JB, Price CJ: Canine medicine and therapetics, 3rd Ed., Chapter 11:417-448; Chapter 23:771 -808. Blackwell Science, (1995).
  • 44- Hoffman R and Wasserman LR: Natura! history and management of polycythemia vera. Adv. Intem. Med., 24:255-285,(1979).
  • 45- Barragry TB: Veterinary Drug Therapy Chapter 36: 919- 940. Lea-Febıger, USA, (1994).
Toplam 45 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Ebubekir Ceylan Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2006
Yayımlandığı Sayı Yıl 2006 Cilt: 9 Sayı: 2

Kaynak Göster

APA Ceylan, E. (2006). POLİSİTEMİ. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 9(2), 33-39.
AMA Ceylan E. POLİSİTEMİ. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. Haziran 2006;9(2):33-39.
Chicago Ceylan, Ebubekir. “POLİSİTEMİ”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9, sy. 2 (Haziran 2006): 33-39.
EndNote Ceylan E (01 Haziran 2006) POLİSİTEMİ. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9 2 33–39.
IEEE E. Ceylan, “POLİSİTEMİ”, Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, c. 9, sy. 2, ss. 33–39, 2006.
ISNAD Ceylan, Ebubekir. “POLİSİTEMİ”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 9/2 (Haziran 2006), 33-39.
JAMA Ceylan E. POLİSİTEMİ. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2006;9:33–39.
MLA Ceylan, Ebubekir. “POLİSİTEMİ”. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, c. 9, sy. 2, 2006, ss. 33-39.
Vancouver Ceylan E. POLİSİTEMİ. Yüzüncü Yıl Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2006;9(2):33-9.