BÖBREK BİYOPSİ ÖRNEKLERİNİN KLİNİK VE HİSTOPATOLOJİK AÇIDAN DEĞERLENDİRİLMESİ

Yıl 2020, Cilt: 6 Sayı: 3, 315 - 322, 31.12.2020

Recep Demirci Berrak Sahtiyancı Ali Bakan Okan Akyüz Yasemin Özlük Işın Kılıçaslan

Öz

Bu çalışmada Ocak 2015 ve Aralık 2019 tarihleri arasında yapılan böbrek biyopsilerinin klinik ve patolojik açıdan değerlendirilmesi amaçlandı. Bu çalışmada Ocak 2015- Aralık 2019 tarihleri arasında Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi İç Hastalıkları Kliniğinde yapılan 64 hastanın böbrek biyopsi verileri retrospektif olarak analiz edildi. Böbrek biyopsilerinin hepsi ultrasonografi eşliğinde yapılmış olup tamamı nativ böbrek biyopsisiydi. Hastalara ait demografik, klinik ve laboratuvar bilgileri hastane kayıtlarından elde edildi. Çalışma grubunun 26’sı (%41.2) erkek, 38’i (%58.8) kadın olup yaş ortalaması 44.41 ± 8.55 yıl idi. Çalışmada biyopsi endikasyonları arasında ilk sırada nefrotik düzeyde proteinüri ve hematüri (%65.1) bulunuyordu. Biyopsi sonucunda en sık fokal segmental glomerüloskleroz (FSGS) (%29.7) saptanırken ikinci sırada ise membranöz glomerülonefrit (MGN) (%20,4) saptandı. Sonuç olarak çalışmada en sık biyopsi endikasyonu nefrotik düzeyde proteinüri ve hematüri olarak saptandı. Biyopsi sonucunda en sık saptanan patolojinin FSGS olması dikkat çekiciydi.

Anahtar Kelimeler

böbrek biyopsisi, fokal segmental glomeruloskleroz, membranöz glomerulonefrit

CLINICAL AND HISTOPATHOLOGICAL EVALUATION OF KIDNEY BIOPSY SAMPLES

Öz

The aim of this study was to evaluate the clinical and pathological evaluation of renal biopsies performed between January 2015 and December 2019. In this study, renal biopsy data of 64 patients who were performed in the Internal Medicine Clinic of Kanuni Sultan Suleyman Training and Research Hospital between January 2015 and December 2019 were analyzed retrospectively. All renal biopsies were performed under ultrasonography guidance and all were native kidney biopsies. Demographic, clinical and laboratory data of the patients were obtained from hospital records. The study group consisted of 26 (41.2%) males and 38 (58.8%) females with a mean age of 44.41 ± 8.55 years. In the study, nephrotic proteinuria and hematuria were the most common biopsy indications (65.1%). Biopsy revealed the most common focal segmental glomerulosclerosis (FSGS) (29.7%) and followed membranous glomerulonephritis (MGN) (20.4%). In conclusion, the most common indication for biopsy was nephrotic proteinuria and hematuria. It was noteworthy that the most common pathology detected by biopsy was FSGS.

Anahtar Kelimeler

focal segmental glomerulosclerosis, renal, membranous glomerulonephritis

Kaynakça

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