Case Report
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Candidemia due to Candida glabrata in a non-immunosuppressed hospitalized patient

Year 2022, , 463 - 465, 22.10.2022
https://doi.org/10.38053/acmj.1148163

Abstract

Opportunistic fungal infections due to Candida species in immunosuppressed patients appearas significant causes of mortality and morbidity. Candida infections and candidemia can also be encounteredamong immunocompetent patients with underlying predisposing factors. This paper presents a 72-year-old diabetic male patient who developed candidemia due to Candida glabrata complex without any underlying immunosuppressive disease. The patient fully recovered after a total of 23 days of anidulafungin treatment.

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References

  • Antinori S, Milazzo L, Sollima S, Galli M, Corbellino M. Candidemia and invasive candidiasis in adults: a narrative review. Eur J Intern Med 2016; 34: 21-8.
  • Pappas PG, Kauffman CA, Andes DR, et al. Clinical practice guideline for the management of candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis 2016; 62: e1–e50.
  • Zakhem AE, Istambouli R, Alkozah M, et al. Predominance of Candida glabrata among non-albicans Candida species in a 16-year study of candidemia at a tertiary care center in Lebanon. Pathogens 2021; 10: 82.
  • Lortholary O,Renaudat C, Sitbon K, et al. Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris Area, 2002–2010). Intensive Care Med 2014; 40: 1303–12.
  • Colombo AL, Guimarães T, Sukienik T, et al. Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period. Intensive Care Med 2014; 40: 1489–98.
  • Radhouane K, Bedioui A, Yedeas MD, et al. Brain abscess due to Candida glabrata in an immunocompetent patient. a case report with update and literature review. ID Cases 2020; 22: e00996.
  • Angel-Moreno A, Boronat M, Bolaños M, Carrillo A, González S, Pérez Arellano JL. Candida glabrata fungemia cured by antibiotic-lock therapy: case report and short review. J Infect 2005; 51: e85-7.
  • Colomba C, Trizzino M, Imburgia C, Madonia S, Siracusa L, Giammanco GM. Candida glabrata meningitis and endocarditis: a late severe complication of candidemia. Int J Infect Dis 2014; 29: 174-5.
  • Schiedo RM, Lavelle W, Sun MH. Lumbar spinal Candida glabrata treated without surgical intervention: a case report. Cureus 2017; 9: e1371.
  • Falcone M, TiseoG, TasciniC, et al. Assessment of risk factors for candidemia in non-neutropenic patients hospitalized in Internal Medicine wards: a multicenter study. Eur J Intern Med 2017; 41: 33-8.
  • Cheng YR, Lin LC, Young TG, Liu CE, Chen CH, Tsay RW. Risk factors for candidemia-related mortality at a medical center in central Taiwan. J Microbiol Immunol Infect 2006; 39: 155-61.
Year 2022, , 463 - 465, 22.10.2022
https://doi.org/10.38053/acmj.1148163

Abstract

Project Number

-

References

  • Antinori S, Milazzo L, Sollima S, Galli M, Corbellino M. Candidemia and invasive candidiasis in adults: a narrative review. Eur J Intern Med 2016; 34: 21-8.
  • Pappas PG, Kauffman CA, Andes DR, et al. Clinical practice guideline for the management of candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis 2016; 62: e1–e50.
  • Zakhem AE, Istambouli R, Alkozah M, et al. Predominance of Candida glabrata among non-albicans Candida species in a 16-year study of candidemia at a tertiary care center in Lebanon. Pathogens 2021; 10: 82.
  • Lortholary O,Renaudat C, Sitbon K, et al. Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris Area, 2002–2010). Intensive Care Med 2014; 40: 1303–12.
  • Colombo AL, Guimarães T, Sukienik T, et al. Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period. Intensive Care Med 2014; 40: 1489–98.
  • Radhouane K, Bedioui A, Yedeas MD, et al. Brain abscess due to Candida glabrata in an immunocompetent patient. a case report with update and literature review. ID Cases 2020; 22: e00996.
  • Angel-Moreno A, Boronat M, Bolaños M, Carrillo A, González S, Pérez Arellano JL. Candida glabrata fungemia cured by antibiotic-lock therapy: case report and short review. J Infect 2005; 51: e85-7.
  • Colomba C, Trizzino M, Imburgia C, Madonia S, Siracusa L, Giammanco GM. Candida glabrata meningitis and endocarditis: a late severe complication of candidemia. Int J Infect Dis 2014; 29: 174-5.
  • Schiedo RM, Lavelle W, Sun MH. Lumbar spinal Candida glabrata treated without surgical intervention: a case report. Cureus 2017; 9: e1371.
  • Falcone M, TiseoG, TasciniC, et al. Assessment of risk factors for candidemia in non-neutropenic patients hospitalized in Internal Medicine wards: a multicenter study. Eur J Intern Med 2017; 41: 33-8.
  • Cheng YR, Lin LC, Young TG, Liu CE, Chen CH, Tsay RW. Risk factors for candidemia-related mortality at a medical center in central Taiwan. J Microbiol Immunol Infect 2006; 39: 155-61.
There are 11 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Melek Sena Altun 0000-0002-5612-7305

Salih Cesur 0000-0003-4960-7375

Esra Kaya Kılıç 0000-0002-3270-4841

Cigdem Ataman Hatipoglu 0000-0002-1104-8232

Özlem Öztekin 0000-0001-5535-762X

Sami Kınıklı 0000-0002-9661-7851

Project Number -
Publication Date October 22, 2022
Published in Issue Year 2022

Cite

AMA Altun MS, Cesur S, Kaya Kılıç E, Ataman Hatipoglu C, Öztekin Ö, Kınıklı S. Candidemia due to Candida glabrata in a non-immunosuppressed hospitalized patient. Anatolian Curr Med J / ACMJ / acmj. October 2022;4(4):463-465. doi:10.38053/acmj.1148163

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