Research Article

Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview

Volume: 7 Number: 6 October 26, 2025
TR EN

Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview

Abstract

Aims: This study aims to provide a comprehensive bibliometric analysis of the literature on experimental periodontal and peri implant disease in animal models (EPPIDA), examining current trends, thematic developments, and the global contributions to this field. The focus is on understanding the evolution of research themes, publication growth, and the impact of animal models in EPPIDA studies. Methods: This bibliometric analysis was conducted on 925 articles from the Web of Science database, covering the period from 1980 to 2024. The study utilized Bibliometrix software (version 4.3.0) to analyze the data, focusing on article performance, word analysis, collaboration network, and thematic analysis. Results: The findings reveal a significant increase in annual publications in EPPIDA research. Brazil contributed the most with 186 publications, Berglundh T (n=1453) was the most highly cited author and the Journal of Periodontology was the most influential journal. Conclusion: This bibliometric study provides valuable insights into the evolving landscape of EPPIDA research. The study underscores the need for continued focus on animal models to ensure the development of scientifically sound and clinically viable treatments for periodontal diseases. The findings offer guidance for future research directions and highlight key trends in the field. These insights provide a foundation for designing future experimental and translational studies, thereby facilitating the development of more effective clinical strategies for the prevention and management of periodontal and peri-implant diseases.

Keywords

Supporting Institution

none

Ethical Statement

This study is a bibliometric analysis and therefore does not require ethics committee approval.

Thanks

none

References

  1. Cui Z, Wang P, Gao W. Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic. Front Cell Infect Microbiol. 2025;15:1517154. doi:10.3389/fcimb.2025.1517154
  2. Struillou X, Boutigny H, Soueidan A, Layrolle P. Experimental animal models in periodontology: a review. Open Dent J. 2010;4(1):37-47. doi:10. 2174/1874210601004010037
  3. Staubli N, Schmidt JC, Rinne CA, Signer-Buset SL, Rodriguez FR, Walter C. Animal experiments in periodontal and peri-implant research: are there any changes? Dent J (Basel). 2019;7(2):46. doi:10.3390/dj7020046
  4. Javed F, Romanos GE. Efficacy of photobiomodulation in the management of experimentally-induced peri implant osseous defects: an evidence-based review of studies on animal-models. J Dent. 2025;159: 105833. doi:10.1016/j.jdent.2025.105833
  5. Hasuike A, Easter QT, Clark D, Byrd KM. Application of single-cell genomics to animal models of periodontitis and peri-implantitis. J Clin Periodontol. 2025;52(2):268-279. doi:10.1111/jcpe.14093
  6. Daghrery A, Dal-Fabbro R, Dos Reis-Prado AH, et al. Guidance on the assessment of the functionality of biomaterials for periodontal tissue regeneration: methodologies and testing procedures. Dent Mater. 2025; 41(3):306-318. doi:10.1016/j.dental.2024.12.018
  7. Kantarci A, Hasturk H, Van Dyke TE. Animal models for periodontal regeneration and peri-implant responses. Periodontol 2000. 2015;68(1): 66-82. doi:10.1111/prd.12052
  8. Li J, Zhao YN, Wang YH, et al. Animal models of oral infectious diseases. Front Oral Health. 2025;6:1571492. doi:10.3389/froh.2025.1571492

Details

Primary Language

English

Subjects

Oral Implantology, Oral Medicine and Pathology, Periodontics

Journal Section

Research Article

Publication Date

October 26, 2025

Submission Date

August 28, 2025

Acceptance Date

October 10, 2025

Published in Issue

Year 2025 Volume: 7 Number: 6

APA
Ercan, N., Ateş Yıldırım, E., Akgül, Z., & Meracı Yıldıran, B. (2025). Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview. Anatolian Current Medical Journal, 7(6), 874-885. https://doi.org/10.38053/acmj.1773361
AMA
1.Ercan N, Ateş Yıldırım E, Akgül Z, Meracı Yıldıran B. Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview. Anatolian Curr Med J / ACMJ / acmj. 2025;7(6):874-885. doi:10.38053/acmj.1773361
Chicago
Ercan, Nuray, Esra Ateş Yıldırım, Zeynep Akgül, and Bilge Meracı Yıldıran. 2025. “Trends in Animal Research on Experimental Periodontal and Peri-Implant Diseases: A Bibliometric Overview”. Anatolian Current Medical Journal 7 (6): 874-85. https://doi.org/10.38053/acmj.1773361.
EndNote
Ercan N, Ateş Yıldırım E, Akgül Z, Meracı Yıldıran B (October 1, 2025) Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview. Anatolian Current Medical Journal 7 6 874–885.
IEEE
[1]N. Ercan, E. Ateş Yıldırım, Z. Akgül, and B. Meracı Yıldıran, “Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview”, Anatolian Curr Med J / ACMJ / acmj, vol. 7, no. 6, pp. 874–885, Oct. 2025, doi: 10.38053/acmj.1773361.
ISNAD
Ercan, Nuray - Ateş Yıldırım, Esra - Akgül, Zeynep - Meracı Yıldıran, Bilge. “Trends in Animal Research on Experimental Periodontal and Peri-Implant Diseases: A Bibliometric Overview”. Anatolian Current Medical Journal 7/6 (October 1, 2025): 874-885. https://doi.org/10.38053/acmj.1773361.
JAMA
1.Ercan N, Ateş Yıldırım E, Akgül Z, Meracı Yıldıran B. Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview. Anatolian Curr Med J / ACMJ / acmj. 2025;7:874–885.
MLA
Ercan, Nuray, et al. “Trends in Animal Research on Experimental Periodontal and Peri-Implant Diseases: A Bibliometric Overview”. Anatolian Current Medical Journal, vol. 7, no. 6, Oct. 2025, pp. 874-85, doi:10.38053/acmj.1773361.
Vancouver
1.Nuray Ercan, Esra Ateş Yıldırım, Zeynep Akgül, Bilge Meracı Yıldıran. Trends in animal research on experimental periodontal and peri-implant diseases: a bibliometric overview. Anatolian Curr Med J / ACMJ / acmj. 2025 Oct. 1;7(6):874-85. doi:10.38053/acmj.1773361

 

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