Parametrial resection in cervical cancer: optimizing oncological outcomes and complications
Abstract
Aims: To evaluate the impact of the extent of parametrial resection on oncological outcomes and postoperative complications in early-stage cervical cancer patients undergoing type III radical hysterectomy.
Methods: A retrospective analysis was conducted on 38 patients treated between 2011 and 2022 with type III radical hysterectomy and pelvic/paraaortic lymphadenectomy. Parametrial length and volume were measured, and postoperative complications were assessed using Clavien-Dindo Grade III and IV criteria. Associations between parametrial resection extent, complications, blood transfusion, recurrence, and mortality were analyzed using univariate and multivariate logistic regression, adjusting for tumor stage.
Results: Median follow-up was 32.0 months. Major complications occurred in 11 patients (28.9%): ureteral injury (n=6), bladder dysfunction (n=2), fascial dehiscence (n=2), and pelvic abscess (n=1). Greater parametrial length significantly correlated with these complications (p=0.007) and transfusion needs (p=0.023). Recurrence (26.3%) and mortality (21.1%) were independent of resection extent. Each 1 cm increase in parametrial length increased the odds of major complications (OR=2.953, 95% CI 1.245-7.004) and transfusion (OR=2.117 95% CI 1.072-4.181).
Conclusion: These findings suggest that limiting the lateral extent of parametrial resection may reduce morbidity. Although our limited, retrospective cohort did not show a significant negative impact on recurrence or mortality, the statistical power is insufficient to definitively confirm oncological safety. This supports a risk-adapted approach, underscoring the need for larger prospective studies.
Keywords
Supporting Institution
None
Ethical Statement
Ethics committee approval was received for this study from the Hatay Mustafa Kemal University ethics committee decision number 17 dated 6.11.23. This study was performed in line with the principles of the Declaration of Helsinki
Thanks
None
References
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Details
Primary Language
English
Subjects
Obstetrics and Gynaecology
Journal Section
Research Article
Publication Date
May 22, 2026
Submission Date
February 3, 2026
Acceptance Date
April 5, 2026
Published in Issue
Year 2026 Volume: 8 Number: 3
APA
Beyazıt, A., Dolapçıoğlu, K. S., & Erdem, M. (2026). Parametrial resection in cervical cancer: optimizing oncological outcomes and complications. Anatolian Current Medical Journal, 8(3), 429-434. https://izlik.org/JA89XS45YY
AMA
1.Beyazıt A, Dolapçıoğlu KS, Erdem M. Parametrial resection in cervical cancer: optimizing oncological outcomes and complications. Anatolian Curr Med J / ACMJ / acmj. 2026;8(3):429-434. https://izlik.org/JA89XS45YY
Chicago
Beyazıt, Ahmet, Kenan Serdar Dolapçıoğlu, and Mehmet Erdem. 2026. “Parametrial Resection in Cervical Cancer: Optimizing Oncological Outcomes and Complications”. Anatolian Current Medical Journal 8 (3): 429-34. https://izlik.org/JA89XS45YY.
EndNote
Beyazıt A, Dolapçıoğlu KS, Erdem M (May 1, 2026) Parametrial resection in cervical cancer: optimizing oncological outcomes and complications. Anatolian Current Medical Journal 8 3 429–434.
IEEE
[1]A. Beyazıt, K. S. Dolapçıoğlu, and M. Erdem, “Parametrial resection in cervical cancer: optimizing oncological outcomes and complications”, Anatolian Curr Med J / ACMJ / acmj, vol. 8, no. 3, pp. 429–434, May 2026, [Online]. Available: https://izlik.org/JA89XS45YY
ISNAD
Beyazıt, Ahmet - Dolapçıoğlu, Kenan Serdar - Erdem, Mehmet. “Parametrial Resection in Cervical Cancer: Optimizing Oncological Outcomes and Complications”. Anatolian Current Medical Journal 8/3 (May 1, 2026): 429-434. https://izlik.org/JA89XS45YY.
JAMA
1.Beyazıt A, Dolapçıoğlu KS, Erdem M. Parametrial resection in cervical cancer: optimizing oncological outcomes and complications. Anatolian Curr Med J / ACMJ / acmj. 2026;8:429–434.
MLA
Beyazıt, Ahmet, et al. “Parametrial Resection in Cervical Cancer: Optimizing Oncological Outcomes and Complications”. Anatolian Current Medical Journal, vol. 8, no. 3, May 2026, pp. 429-34, https://izlik.org/JA89XS45YY.
Vancouver
1.Ahmet Beyazıt, Kenan Serdar Dolapçıoğlu, Mehmet Erdem. Parametrial resection in cervical cancer: optimizing oncological outcomes and complications. Anatolian Curr Med J / ACMJ / acmj [Internet]. 2026 May 1;8(3):429-34. Available from: https://izlik.org/JA89XS45YY
