Biological and Physiological Activities of Whey Proteins and Their Derivatives

Year 2010, Volume: 8 Issue: 1, 23 - 31, 01.02.2010

Filiz Gür Melih Güzel Nilgün Öncül Zeliha Yıldırım Metin Yıldırım

Abstract

Milk proteins have received increasing attention as potential ingredients of functional foods reducing or preventing the risk of diet-related diseases, such as cardiovascular disease, diabetes type two and obesity. Due to these properties, studies have recently been focused on milk proteins and their bioactive peptides. Such peptides are inactive within the sequence of the milk protein and can be released by digestive enzymes during gastrointestinal transit or by starter cultures used for fermentation or ripening of dairy products. Bioactive peptides have been defined as specific protein fragments that have a positive impact on body functions and may ultimately influence human health. Whey contains a multitude of biologically active proteins and peptides. Physiologically active serum proteins are serum albumine, immunoglobulins, proteose-peptone, lactoferrin, lactoperoxidase and growth factors. In addition to these, enzymatic degradation of serum proteins releases a number of bioactive peptides such as α-lactophorin, β-lactophorin, βlactotensin, lactokinin, albutensin, serophorin and lactoferricin

Keywords

Milk, Whey proteins, Bioactive peptides, Human health

Süt Serum Proteinleri ve Türevlerinin Biyolojik ve Fizyolojik Aktiviteleri

Abstract

Süt proteinlerine, kalp-damar rahatsızlıkları, tip II diyabet ve obezite gibi beslenmeye bağlı olarak ortaya çıkan hastalıkların görülme riskinin azaltılmasında veya önlenmesinde potansiyel fonksiyonel gıda bileşenleri olarak oldukça fazla ilgi duyulmaktadır. Buna bağlı olarak son yıllarda süt proteinleri ve bunlardan kaynaklanan biyoaktif peptidler üzerinde çalışmalar yoğunlaşmıştır. Biyoaktif peptidler, süt protein molekülerinin içerisinde inaktif olarak bulunan, ancak sütün tüketilmesiyle beraber sindirim sisteminde parçalanması veya süt ürünlerinin fermantasyonu ya da olgunlaşması için kullanılan starter kültürlerin aktiviteleri sonucunda açığa çıkmaktadırlar. Biyoaktif peptidler, vücut fonksiyonları ve sağlık üzerine doğrudan pozitif etkileri bulunan proteinler olarak tanımlanmaktadır. Serum proteinleri, biyoaktif özellikteki birçok protein ve peptidleri içermektedir. Serum albümini, immunoglobulinler, proteoz-peptonlar, laktoferrin, laktoperoksidaz ve büyüme faktörleri fizyolojik aktiviteye sahip olan proteinlerdir. Bunların yanı sıra, serum proteinlerinin enzimatik parçalanması sonucunda da α-laktoforin, β-laktoforin, β-laktotensin, laktokinin, albutensin, seroforin, laktoferrisin gibi birçok biyoaktif peptid açığa çıkmaktadır

Keywords

Süt, Serum proteinleri, Biyoaktif peptidler, İnsan sağlığı

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