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Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species

Year 2011, Volume: 20 Issue: 1, 40 - 44, 23.03.2012

Abstract

Özet: Ülkemizde ve dünyada balık üretimi yüksek ölüm oranlarından oldukça olumsuzyönde etkilenmektedir. Ayrıca akuvakültür sistemindeki ekonomik kayıpların ve ölümlerinçoğununun enfeksiyöz hastalıklardan olduğu düşünülmektedir. Diyetlere ilave edilerekkullanılan bağışıklığı destekleyici maddeler, balıkların taşınması, transferi, aşılanması gibiyüksek stres oluşturan durumlarda doğuştan gelen savunma sistemlerini geliştirmek içinkullanılır. Bu derlemede, balık diyetlerine katılan levamizolün bazı balık türlerinde hastalıklarakarşı direnç ve bağışıklık sistemi üzerinde yaptığı etkilerin araştırılması hedeflenmiştir.Anahtar Kelimeler: Levamizol, hastalıklara direnç, bağışıklığa etki, balık.
Abstract: The production of fish is often hampered by high mortality rates in our countryand in world, and it is believed that most of this economic loss due to infectious diseases isin aquaculture sector. The use of immunostimulants, as dietary supplements, can improvethe innate defence of animals providingresistance to pathogens during periods of highstress, such as grading, reproduction, sea transfer and vaccination. In this review, it wasaimed to present the effect of levamisole added to fish diets on the immune response anddisease resistance of some fish species.Key Words: Levamisole, disease resistance, immune response, fish.

References

  • Aoki, T., 1992. Chemotherapy and drug resistance in fish farms in Japan. In: Shariff, M., Subasighe, R.P., Arthur, J.R. Eds. , Diseases in Asian Aquaculture Vol. 1. Fish Health Section, Asian Fisheries Society, Manila, Philippines,. 519–529.
  • Baba, T., Watase, Y., Yoshinaga, Y., 1993. Activation of mononuclear phagocyte function by levamisole immersion in carp. Nippon Suisan Gakkaishi, 59, 301–307.
  • Baruah, N.D., Prasad, K.P., 2001. Efficacy of levamisole as an immunostimulant in Macrobrachium Rosenbergii (De man). J. Aquac. Trop. 16, 149–158.
  • Cuesta, A., Esteban, M.A., Meseguer J., 2002. Levamisole is a potent enhancer of gilthead seabream natural cytotoxic activity, Veterinary Immunology and Immunopathology, 89, 169-174.
  • Cuesta, A., Meseguer, J. Ve Esteban M.A., 2004. Total serum immunoglobulin M levels are affected by immunomodulators in seabream (Sparus aurata L.) ,Veterinary Immunology and Immunopathology.101, 203-210.
  • Findlay, V.L., Zilberg, D., Munday, B.L., 2000. Evaluation of levamisole as a treatment for amoebic gill disease of Atlantic salmon, Salmo salar L. J. Fish Dis. 23, 193–198.
  • Geets, A., Liewes, E.W., Ollevier, F., 1992. Efficacy of some antihelminthics against the swimbladder nematode Anguillicola crassus of eel Anguilla anguilla under saltwater conditions. Dis. Aquat. Org. 13, 123–128.
  • Hirazawa, N., Ohtaka, T., Hata, K., 2000. Challenge trials on the anthelmintic effect of drugs and natural agents against the monogenean Heterobothrium okamotoi in the tiger puffer Takifugu rubripe, 188, 1-13.
  • Kajita, Y., Sakai, M., Atsuta, S., Kobayashi, M., 1990. The immunomodulatory effects of levamisole on rainbow trout, Oncorhynchus mykiss. Fish Pathol. 25, 93–98.
  • Leano, E.M., Guo, J., Chang, S., Liao, I.C., 2003. Levamisole enhances non-specific immune response of cobia (Rachycentron canadum) fingerlings. J. Fish. Soc. Taiwan 30, 321–330.
  • Li, G., Guo, Y., Zhao, D., Qian, P., Sun, J., Xiao, C., Liang L.ve Wang, H., 2005. Effects of levamisole on the immune response and disease resistanceof Clarias fuscus, Aquaculture.
  • Midtlyng, P.J., Reitan, L. J. and Speilberg, L., 1996. Experimental studies on the efficacy and side-effects of intraperitoneal vaccination of Atlantic salmon (Salmo salar L.) against furunculosis, 6, 335-350.
  • Morrison, R.N. , Nowak, B.F. , Carson, J., 2001.The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon Salmo salar L. Aquaculture. 195, 23-33.
  • Mulero,V., Esteban, M. A., Munoz J., ve Meseguer J., 1998. Dietary intake of levamisole enhances the immune response and disease resistance of the marine teleost gilthead
  • Munday, B.L., Zilberg, D., 2003. Efficacy of and toxicity associated with, the use of levamisole in seawater to treat amoebic gill disease. Bull. Eur. Assoc. Fish Pathol. 23, 3–6.seabream (Sparus aurata L.). 8, 49-62.
  • Olivier, G., Evelyn, T.P.T., Lallier, R., 1985. Immunity to Aeromonas salmonicida in coho salmon (Oncorhynchus kisutch) induced by modified Freund’s complete adjuvant: its non specific nature and the probable role of macrophages in the phenomenon. Dev. Comp. Immunol. 9, 419–432.
  • Renoux, G., 1980. The general immunopharmacology of levamisole. Drugs 19, 89–99.
  • Sahoo, P. K. ve Mukherijee S. C., 2002. The effect of dietary immunomodulation upon Edwardsiella tarda vaccination in healthy and immunocompromised Indian major carp (Labeo rohita). Fish & Shellfish Immunology .12, 1-6.
  • Sahoo, P. K. and Mukherjee , S. C., 2002. The effect of dietary immunomodulation upon Edwardsiella tarda vaccination in healthy and immunocompromised Indian major carp (Labeo rohita). Fish & Shellfish Immunology, 12, 1-16.
  • Sakai, M., 1999. Current research status of fish immunostimulants, Aquaculture. 172, 63- 92.
  • Siwicki, A.K., 1987. Immunomodulating activity of levamisole in spawners carp (Cyprinus carpio L.) . J. Fish Biol. 31, 245–246.
  • Siwicki, A.K., Korwin-Kossakowski, M., 1988. The influence of levamisole on the growth of carp (Cyprinus carpio L.) larvae. J. Appl. Ichthyol. 4, 178–181.
  • Siwicki, A.K., 1989. Immunostimulating influence of levamisole on nonspecific immunity in carp (Cyprinus carpio) . Dev. Comp. Immunol. 13, 87–91.
  • Symoens, I., Rosenthall, M., 1977. Levamisole in the modulation of the immune responses. The current experimental and clinical state. J. Reticuloendothel. Soc. 21, 175–221.
Year 2011, Volume: 20 Issue: 1, 40 - 44, 23.03.2012

Abstract

References

  • Aoki, T., 1992. Chemotherapy and drug resistance in fish farms in Japan. In: Shariff, M., Subasighe, R.P., Arthur, J.R. Eds. , Diseases in Asian Aquaculture Vol. 1. Fish Health Section, Asian Fisheries Society, Manila, Philippines,. 519–529.
  • Baba, T., Watase, Y., Yoshinaga, Y., 1993. Activation of mononuclear phagocyte function by levamisole immersion in carp. Nippon Suisan Gakkaishi, 59, 301–307.
  • Baruah, N.D., Prasad, K.P., 2001. Efficacy of levamisole as an immunostimulant in Macrobrachium Rosenbergii (De man). J. Aquac. Trop. 16, 149–158.
  • Cuesta, A., Esteban, M.A., Meseguer J., 2002. Levamisole is a potent enhancer of gilthead seabream natural cytotoxic activity, Veterinary Immunology and Immunopathology, 89, 169-174.
  • Cuesta, A., Meseguer, J. Ve Esteban M.A., 2004. Total serum immunoglobulin M levels are affected by immunomodulators in seabream (Sparus aurata L.) ,Veterinary Immunology and Immunopathology.101, 203-210.
  • Findlay, V.L., Zilberg, D., Munday, B.L., 2000. Evaluation of levamisole as a treatment for amoebic gill disease of Atlantic salmon, Salmo salar L. J. Fish Dis. 23, 193–198.
  • Geets, A., Liewes, E.W., Ollevier, F., 1992. Efficacy of some antihelminthics against the swimbladder nematode Anguillicola crassus of eel Anguilla anguilla under saltwater conditions. Dis. Aquat. Org. 13, 123–128.
  • Hirazawa, N., Ohtaka, T., Hata, K., 2000. Challenge trials on the anthelmintic effect of drugs and natural agents against the monogenean Heterobothrium okamotoi in the tiger puffer Takifugu rubripe, 188, 1-13.
  • Kajita, Y., Sakai, M., Atsuta, S., Kobayashi, M., 1990. The immunomodulatory effects of levamisole on rainbow trout, Oncorhynchus mykiss. Fish Pathol. 25, 93–98.
  • Leano, E.M., Guo, J., Chang, S., Liao, I.C., 2003. Levamisole enhances non-specific immune response of cobia (Rachycentron canadum) fingerlings. J. Fish. Soc. Taiwan 30, 321–330.
  • Li, G., Guo, Y., Zhao, D., Qian, P., Sun, J., Xiao, C., Liang L.ve Wang, H., 2005. Effects of levamisole on the immune response and disease resistanceof Clarias fuscus, Aquaculture.
  • Midtlyng, P.J., Reitan, L. J. and Speilberg, L., 1996. Experimental studies on the efficacy and side-effects of intraperitoneal vaccination of Atlantic salmon (Salmo salar L.) against furunculosis, 6, 335-350.
  • Morrison, R.N. , Nowak, B.F. , Carson, J., 2001.The histopathological effects of a levamisole-adjuvanted Vibrio anguillarum vaccine on Atlantic salmon Salmo salar L. Aquaculture. 195, 23-33.
  • Mulero,V., Esteban, M. A., Munoz J., ve Meseguer J., 1998. Dietary intake of levamisole enhances the immune response and disease resistance of the marine teleost gilthead
  • Munday, B.L., Zilberg, D., 2003. Efficacy of and toxicity associated with, the use of levamisole in seawater to treat amoebic gill disease. Bull. Eur. Assoc. Fish Pathol. 23, 3–6.seabream (Sparus aurata L.). 8, 49-62.
  • Olivier, G., Evelyn, T.P.T., Lallier, R., 1985. Immunity to Aeromonas salmonicida in coho salmon (Oncorhynchus kisutch) induced by modified Freund’s complete adjuvant: its non specific nature and the probable role of macrophages in the phenomenon. Dev. Comp. Immunol. 9, 419–432.
  • Renoux, G., 1980. The general immunopharmacology of levamisole. Drugs 19, 89–99.
  • Sahoo, P. K. ve Mukherijee S. C., 2002. The effect of dietary immunomodulation upon Edwardsiella tarda vaccination in healthy and immunocompromised Indian major carp (Labeo rohita). Fish & Shellfish Immunology .12, 1-6.
  • Sahoo, P. K. and Mukherjee , S. C., 2002. The effect of dietary immunomodulation upon Edwardsiella tarda vaccination in healthy and immunocompromised Indian major carp (Labeo rohita). Fish & Shellfish Immunology, 12, 1-16.
  • Sakai, M., 1999. Current research status of fish immunostimulants, Aquaculture. 172, 63- 92.
  • Siwicki, A.K., 1987. Immunomodulating activity of levamisole in spawners carp (Cyprinus carpio L.) . J. Fish Biol. 31, 245–246.
  • Siwicki, A.K., Korwin-Kossakowski, M., 1988. The influence of levamisole on the growth of carp (Cyprinus carpio L.) larvae. J. Appl. Ichthyol. 4, 178–181.
  • Siwicki, A.K., 1989. Immunostimulating influence of levamisole on nonspecific immunity in carp (Cyprinus carpio) . Dev. Comp. Immunol. 13, 87–91.
  • Symoens, I., Rosenthall, M., 1977. Levamisole in the modulation of the immune responses. The current experimental and clinical state. J. Reticuloendothel. Soc. 21, 175–221.
There are 24 citations in total.

Details

Primary Language tr;en
Journal Section Research Articles
Authors

Mehtap Bayır This is me

Telat Yanık This is me

Publication Date March 23, 2012
Published in Issue Year 2011 Volume: 20 Issue: 1

Cite

APA Bayır, M., & Yanık, T. (2012). Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species. Alinteri Journal of Agriculture Science, 20(1), 40-44.
AMA Bayır M, Yanık T. Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species. Alinteri Journal of Agriculture Science. March 2012;20(1):40-44.
Chicago Bayır, Mehtap, and Telat Yanık. “Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç Ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species”. Alinteri Journal of Agriculture Science 20, no. 1 (March 2012): 40-44.
EndNote Bayır M, Yanık T (March 1, 2012) Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species. Alinteri Journal of Agriculture Science 20 1 40–44.
IEEE M. Bayır and T. Yanık, “Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species”, Alinteri Journal of Agriculture Science, vol. 20, no. 1, pp. 40–44, 2012.
ISNAD Bayır, Mehtap - Yanık, Telat. “Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç Ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species”. Alinteri Journal of Agriculture Science 20/1 (March 2012), 40-44.
JAMA Bayır M, Yanık T. Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species. Alinteri Journal of Agriculture Science. 2012;20:40–44.
MLA Bayır, Mehtap and Telat Yanık. “Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç Ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species”. Alinteri Journal of Agriculture Science, vol. 20, no. 1, 2012, pp. 40-44.
Vancouver Bayır M, Yanık T. Levamizolün Bazı Balık Türlerinde Hastalıklara Karşı Direnç ve Bağışıklık Sistemi Üzerine Etkileri/Effect of Levamisole on the Immune Response and Disease Resistance of Some Fish Species. Alinteri Journal of Agriculture Science. 2012;20(1):40-4.