Current Approach to Osteoarthritis

Abstract

Osteoarthritis (OA) is a progressive non-inflammatory joint disease that affects particularly cartilage within all structures of the joint. Diagnosis of osteoarthritis is confirmed with clinical and radiological findings. Its incidence rises with age. The joints most frequently affected by osteoarthritis are; knees, hips, spine, distal and proximal interphalangial joints of the hands, first carpometacarpal joint and first metatarsophalengial joint. Typically OA is presented with activity related or mechanical joint pain in earlier periods, while pain may also occur during rest in advanced disease. Treatment modalities for OA are pharmacological, non-pharmacological, intra-articular and surgical. The management of OA should be tailored for each patient and treatment guidelines should be taken into consideration.

Keywords

• osteoarthritis, ethiopathogenesis

Osteoartrite Güncel Yaklaşım

Öz

Özet:

Osteoartrit (OA), başta kıkırdak olmak üzere eklemi oluşturan bütün yapıları etkileyen ilerleyici, inflamatuvar olmayan bir eklem hastalığıdır. OA sıklığı yaşla artmakta olup, tanı klinik ve radyolojik bulgular ile konulmaktadır. En fazla dizler, kalça, omurga ve ellerde distal interfalengial, proksimal interfalengial eklemler, birinci karpometakarpal ve metatarsofalengial eklemler tutulur. En önemli belirti eklem ağrısıdır. Ağrı başlangıçta aktivite ile artarken, ileri dönemlerde dinlenme anında da görülebilir. OA tedavisinde farmakolojik, non-farmakolojik, intraartiküler ve cerrrahi tedavi seçenekleri bulunmaktadır. Mevcut tedavi rehberleri göz önüne alınarak bireye özel hastalık yönetimi oluşturulmalıdır.

Anahtar Kelimeler

• osteoartrit,etiyopatogenez

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