Demir Eksikliğinin Gözden Kaçan Klinik Prezantasyonu; Huzursuz Bacak Sendromu

Abstract

    Huzursuz bacak sendromu (HBS) bacaklarda hareket etme dürtüsü ile kendini gösteren, şikayetlerin istirahatte arttığı, bacaklarda rahatsızlık veren duyumlar ile karakterize uyku ilişkili bir hastalık olarak tanımlanmış nörolojik duyusal-motor bir bozukluktur. Hastalığın primer (idiyopatik) HBS ve sekonder (semptomatik) HBS olmak üzere iki formu vardır. İdiopatik form genetik ve kaynağı bilinmeyen etyolojik nedenleri içerirken, sekonder formun çok çeşitli sebepleri olabilir. Sekonder HBS’nin etiyolojik sebepleri değerlendirildiğinde %43’ ünün anemi ile birlikte veya anemi olmaksızın sistemik demir eksikliği ilişkili olduğu tespit edilmiştir. Bu yazıda; son 2 yılda 8 kez tam kan bağışında bulunan ve ferritin düşüklüğüne atfedilen sekonder HBS‘ lu bir olgumuzu sunduk. 

Keywords

• Demir Eksikliği,Huzursuz Bacak Sendromu,Uyku Bozukluğu

Overlooked Clinical Presentation of Iron Deficiency; Restless Leg Syndrome

Abstract

Restless legs syndrome (RLS) is a common sleep related neurological sensory-motor disorder which is characterized by uncomfortable and unpleasant sensations in the legs, worsening of complaints during periods of rest that manifests as an irresistible urge to move the body to relieve the uncomfortable sensations. The RLS includes two groups in general: primary (idiopathic) RLS and secondary RLS. While the idiopathic group includes unknown genetics and etiological causes, the secondary group may have a variety of etiological causes. When the etiological causes of secondary RLS were evaluated, it was found that 43% were associated with systemic iron deficiency with or without anemia. In this text; we presented a secondary RLS attributed to low ferritin level in a case who had donated whole blood 8 times in the last 2 years.  

Keywords

• Iron Deficiency,Restless Legs Syndrome,Sleep Disorder

References

1. Allen RP, Earley CJ. Restless legs syndrome: a review of clinical and pathophysiologic features. J Clin Neurophysiol 2001;18(2):128-47.
2. Abetz L, Allen R, Follet A, Washburn T, Earley C, Kirsch J, Knight H. Evaluating the quality of life of patients with restless legs syndrome. Clin Ther 2004;26(6):925-35.
3. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Intern Med 2000;160(14):2137–41.
4. Ekbom KA. Restless legs. Acta Med Scan. 1945;158:1–123.
5. Guo S, Huang J, Jiang H, Han C, Li J, Xu X, Zhang G, Lin Z, Xiong N, Wang T. Restless Legs Syndrome: From Pathophysiology to Clinical Diagnosis and Management. Front Aging Neurosci 2017;9: 171.
6. Ekbom KA. (1960). Restless legs syndrome. Neurology. 1960;10:868–73.
7. Matthews W B. Letter: iron deficiency and restless legs. Br Med J 1976;1(6014):898.
8. O’Keeffe ST, Gavin K, Lavan JN. Iron status and restless legs syndrome in the elderly. Age Ageing 1994;23(3):200–3.

9. Moon HJ, Chang Y, Lee YS, Song HJ, Chang HW, Ku J, et al. T2 relaxometry using 3.0-tesla magnetic resonance imaging of the brain in early- and late-onset restless legs syndrome. J Clin.Neurol.2014; 0(3):197–202.
10. Allen RP, Picchietti DL, Garcia-Borreguero D, et al. International Restless Legs Syndrome Study Group. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med 2014;15(8):860-73.