Type-2 Diabetes Mellitus and Meal Consumption Frequency
Year 2024,
, 217 - 224, 31.05.2024
Sergen Tuğgüm
,
Çiğdem Bozkır
Abstract
Type 2 diabetes is a chronic health problem that continues to threaten human health. Nutrition plays an important role in the etiology of this disease. In addition to the nutrient content consumed, the frequency of meals also affects this disease in many ways. Studies have shown that different eating frequency patterns can increase or decrease the need for food consumption by changing the feelings of hunger-satiety and the levels of some hormones that regulate these sensations. Due to this effect, body weight may increase or decrease and type 2 diabetes can be triggered indirectly. Changing meal frequencies may show this effect directly in individuals with type 2 diabetes through blood parameters associated with the disease or indirectly through body weight and appetite. The purpose of this review is to provide information about the relationship between meal frequency and diabetes, taking into account the complex disease process in type 2 diabetes, and to bring together studies that examine this relationship.
References
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Diabetes, Vol. 10, pp. 365–372.
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perspective. Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1863, pp. 1026–1036.
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the opposite? Pediatric Diabetes, Vol. 20, pp. 5–9.
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and Caloric Restriction. Current Diabetes Reports, Vol. 17, p. 123.
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prevention and management of type 2 diabetes. BMJ (Online), 361, k2234.
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diet and preferences towards type of meal plan in patient with type 2 diabetes mellitus. A cross-sectional
study. Nutrition, Metabolism and Cardiovascular Diseases, 27(7), 642–650.
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diabetes mellitus: The interventional Keto-Med randomized crossover trial. The American Journal of Clinical
Nutrition, 116(3), 640–652.
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approaches to the management of type 2 diabetes1-3. American Journal of Clinical Nutrition, Vol. 97, pp.
505–516.
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245.
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Vol. 365, pp. 1978–1980.
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cantidad de hidratos de carbono en el control metabólico en pacientes con diabetes mellitus tipo 2, sin
terapia con insulina. Revista Médica de Chile, 144(10), 1247–1253.
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Timing and frequency: Implications for cardiovascular disease prevention: A scientific statement from the
american heart association. Circulation, Vol. 135, pp. e96–e121.
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Nutrition Research and Practice, 2(4), 269.
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and young children: A community based study. Italian Journal of Pediatrics, 43(1), 73.
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Humans: The Role of Fasting. Nutrients, 11(4), 719.
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Brief synopsis of controlled feeding studies. The Journal of Nutrition, 141(1), 154–157.
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trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.
American Journal of Clinical Nutrition, 85(4), 981–988.
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associated with blood pressure and hypertension in Korean adults: Analysis of the third korean national
health and nutrition examination survey. European Journal of Clinical Nutrition, 68(4), 481–489.
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frequency on dietary thermogenesis, insulin sensitivity, and fasting lipid profiles in healthy obese women.
American Journal of Clinical Nutrition, 81(1), 16–24.
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Nutrition, 77(S1), S57–S70.
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associated with changes in body mass ındex in adventist health study 2. The Journal of Nutrition, jn244749.
- 32. McCrory, M. A., & Campbell, W. W. (2011). Effects of eating frequency, snacking, and breakfast skipping on
energy regulation: Symposium overview. The Journal of Nutrition, 141(1), 144–147.
- 33. Perrigue, M. M., Drewnowski, A., Wang, C.-Y., & Neuhouser, M. L. (2016). Higher eating frequency does not
decrease appetite in healthy adults. The Journal of Nutrition, 146(1), 59–64.
- 34. Jennings, A., Cassidy, A., Van Sluijs, E. M. F., Griffin, S. J., & Welch, A. A. (2012). Associations between eating
frequency, adiposity, diet, and activity in 9-10 year old healthy-weight and centrally obese children. Obesity,
20(7), 1462–1468.
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biochemical parameters in overweight/obese females? Nutricion Hospitalaria, 36(1), 66–72.
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composition: A meta-analysis. Nutrition Reviews, 73(2), 69–82.
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intake and weight control. Annals of Nutrition and Metabolism, Vol. 57, pp. 36–42.
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Malkova, D. (2020). The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and
stress in long-term weight-loss maintenance: a mixed-methods study. European Journal of Clinical
Nutrition, 74(4), 622–632.
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Endocrinology, 9.
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health. Nutrition Reviews, Vol. 67, pp. 379–390.
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eating frequency and eating behaviours related to appetite from 4 to 7 years of age: Findings from the
population-based birth cohort generation XXI. Appetite, 132, 82–90.
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Nutrition and Metabolic Care, Vol. 17, pp. 458–464.
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and Diabetes, Vol. 2, pp. e26–e26.
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protein intake and greater eating frequency on appetite control in overweight and obese men. Obesity,
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(2013). Meal frequency differentially alters postprandial triacylglycerol and insulin concentrations in obese
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Tip-2 Diabetes Mellitus ve Öğün Tüketim Sıklığı
Year 2024,
, 217 - 224, 31.05.2024
Sergen Tuğgüm
,
Çiğdem Bozkır
Abstract
Tip 2 diyabet, insan sağlığını tehdit etmeye devam eden kronik bir sağlık sorunudur. Beslenme, bu hastalığın etiyolojisinde önemli bir rol oynamaktadır. Tüketilen besin içeriğinin yanı sıra öğün sıklığı da bu hastalığı birçok yönden etkilemektedir. Çalışmalar, farklı yeme sıklığı kalıplarının, açlık-tokluk hissini ve bu hisleri düzenleyen bazı hormonların seviyelerini değiştirerek gıda tüketimi ihtiyacını artırabileceğini veya azaltabileceğini göstermiştir. Bu etki nedeniyle vücut ağırlığı artabilir veya azalabilir ve dolaylı olarak tip 2 diyabet tetiklenebilir. Değişen yemek sıklıkları, bu etkiyi tip 2 diyabetli bireylerde doğrudan hastalıkla ilişkili kan parametreleri yoluyla veya dolaylı olarak vücut ağırlığı ve iştah yoluyla gösterebilir. Bu derlemenin amacı, tip 2 diyabette karmaşık hastalık sürecini dikkate alarak yemek sıklığı ve diyabet arasındaki ilişki hakkında bilgi vermek ve bu ilişkiyi inceleyen çalışmaları bir araya getirmektir.
References
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https://iris.who.int/bitstream/handle/10665/204871/9789241565257_eng.pdf
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Biophysics, 73(1), 181–185.
- 4. Zheng, Y., Ley, S. H., & Hu, F. B. (2018). Global aetiology and epidemiology of type 2 diabetes mellitus and
its complications. Nature Reviews Endocrinology, Vol. 14, pp. 88–98.
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- 6. American Diabetes Association. (2018). 2. classification and diagnosis of diabetes: Standards of medical
care in diabetes. Diabetes Care 41(Suppl 1), 13-27
- 7. Pippitt, K., Li, M., & Gurgle, H. E. (2016). Diabetes mellitus: Screening and diagnosis. American family
physician, 93(2), 103-109.
- 8. Ding, L., Xu, Y., Liu, S., Bi, Y., & Xu, Y. (2018, May). Hemoglobin A1c and diagnosis of diabetes. Journal of
Diabetes, Vol. 10, pp. 365–372.
- 9. Boles, A., Kandimalla, R., & Reddy, P. H. (2017, May). Dynamics of diabetes and obesity: Epidemiological
perspective. Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1863, pp. 1026–1036.
- 10. Malone, J. I., & Hansen, B. C. (2019, February). Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it
the opposite? Pediatric Diabetes, Vol. 20, pp. 5–9.
- 11. Golbidi, S., Daiber, A., Korac, B., Li, H., Essop, M. F., & Laher, I. (2017, December). Health Benefits of Fasting
and Caloric Restriction. Current Diabetes Reports, Vol. 17, p. 123.
- 12. DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, J. J., … Weiss, R. (2015). Type 2
diabetes mellitus. Nature Reviews Disease Primers, 1(1), 15019.
- 13. Evert, A. B., Boucher, J. L., Cypress, M., Dunbar, S. A., Franz, M. J., Mayer-Davis, E. J., … Yancy, W. S. (2014).
Nutrition therapy recommendations for the management of adults with diabetes. Diabetes Care, Vol. 37, pp.
S120–S143.
- 14. Forouhi, N. G., Misra, A., Mohan, V., Taylor, R., & Yancy, W. (2018). Dietary and nutritional approaches for
prevention and management of type 2 diabetes. BMJ (Online), 361, k2234.
- 15. Ponzo, V., Rosato, R., Tarsia, E., Goitre, I., De Michieli, F., Fadda, M., … Bo, S. (2017). Self-reported adherence to
diet and preferences towards type of meal plan in patient with type 2 diabetes mellitus. A cross-sectional
study. Nutrition, Metabolism and Cardiovascular Diseases, 27(7), 642–650.
- 16. Gardner, C. D., Landry, M. J., Perelman, D., Petlura, C., Durand, L. R., Aronica, L., … Kim, S. H. (2022). Effect of a
ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2
diabetes mellitus: The interventional Keto-Med randomized crossover trial. The American Journal of Clinical
Nutrition, 116(3), 640–652.
- 17. Wang, L. L., Wang, Q., Hong, Y., Ojo, O., Jiang, Q., Hou, Y. Y., … Wang, X. H. (2018). The effect of low-
carbohydrate diet on glycemic control in patients with type 2 diabetes mellitus. Nutrients, 10(6).
- 18. Ajala, O., English, P., & Pinkney, J. (2013). Systematic review and meta-analysis of different dietary
approaches to the management of type 2 diabetes1-3. American Journal of Clinical Nutrition, Vol. 97, pp.
505–516.
- 19. Krishan, P., Bedi, O., & Rani, M. (2018, March). Impact of diet restriction in the management of diabetes:
evidences from preclinical studies. Naunyn-Schmiedeberg’s Archives of Pharmacology, Vol. 391, pp. 235–
245.
- 20. Mattson, M. P. (2005). The need for controlled studies of the effects of meal frequency on health. Lancet,
Vol. 365, pp. 1978–1980.
- 21. Leiva, T., Basfi-fer, K., Rojas, P., Carrasco, F., & Ruz O, M. (2016). Efecto del fraccionamiento de la dieta y
cantidad de hidratos de carbono en el control metabólico en pacientes con diabetes mellitus tipo 2, sin
terapia con insulina. Revista Médica de Chile, 144(10), 1247–1253.
- 22. St-Onge, M. P., Ard, J., Baskin, M. L., Chiuve, S. E., Johnson, H. M., Kris-Etherton, P., & Varady, K. (2017). Meal
Timing and frequency: Implications for cardiovascular disease prevention: A scientific statement from the
american heart association. Circulation, Vol. 135, pp. e96–e121.
- 23. Lee, S.-K. (2008). Acculturation, meal frequency, eating-out, and body weight in Korean Americans.
Nutrition Research and Practice, 2(4), 269.
- 24. Belew, A. K., Ali, B. M., Abebe, Z., & Dachew, B. A. (2017). Dietary diversity and meal frequency among infant
and young children: A community based study. Italian Journal of Pediatrics, 43(1), 73.
- 25. Paoli, A., Tinsley, G., Bianco, A., & Moro, T. (2019). The Influence of Meal Frequency and Timing on Health in
Humans: The Role of Fasting. Nutrients, 11(4), 719.
- 26. Leidy, H. J., & Campbell, W. W. (2011). The effect of eating frequency on appetite control and food intake:
Brief synopsis of controlled feeding studies. The Journal of Nutrition, 141(1), 154–157.
- 27. Stote, K. S., Baer, D. J., Spears, K., Paul, D. R., Harris, G. K., Rumpler, W. V., … Mattson, M. P. (2007). A controlled
trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.
American Journal of Clinical Nutrition, 85(4), 981–988.
- 28. Kim, S., Park, G. H., Yang, J. H., Chun, S. H., Yoon, H. J., & Park, M. S. (2014). Eating frequency is inversely
associated with blood pressure and hypertension in Korean adults: Analysis of the third korean national
health and nutrition examination survey. European Journal of Clinical Nutrition, 68(4), 481–489.
- 29. Farshchi, H. R., Taylor, M. A., & Macdonald, I. A. (2005). Beneficial metabolic effects of regular meal
frequency on dietary thermogenesis, insulin sensitivity, and fasting lipid profiles in healthy obese women.
American Journal of Clinical Nutrition, 81(1), 16–24.
- 30. Bellisle, F., McDevitt, R., & Prentice, A. M. (1997). Meal frequency and energy balance. British Journal of
Nutrition, 77(S1), S57–S70.
- 31. Kahleova, H., Lloren, J. I., Mashchak, A., Hill, M., & Fraser, G. E. (2017). Meal frequency and timing are
associated with changes in body mass ındex in adventist health study 2. The Journal of Nutrition, jn244749.
- 32. McCrory, M. A., & Campbell, W. W. (2011). Effects of eating frequency, snacking, and breakfast skipping on
energy regulation: Symposium overview. The Journal of Nutrition, 141(1), 144–147.
- 33. Perrigue, M. M., Drewnowski, A., Wang, C.-Y., & Neuhouser, M. L. (2016). Higher eating frequency does not
decrease appetite in healthy adults. The Journal of Nutrition, 146(1), 59–64.
- 34. Jennings, A., Cassidy, A., Van Sluijs, E. M. F., Griffin, S. J., & Welch, A. A. (2012). Associations between eating
frequency, adiposity, diet, and activity in 9-10 year old healthy-weight and centrally obese children. Obesity,
20(7), 1462–1468.
- 35. Yildiran, H., & Mercanligil, S. M. (2019). Does increasing meal frequency improve weight loss and some
biochemical parameters in overweight/obese females? Nutricion Hospitalaria, 36(1), 66–72.
- 36. Schoenfeld, B. J., Aragon, A. A., & Krieger, J. W. (2015). Effects of meal frequency on weight loss and body
composition: A meta-analysis. Nutrition Reviews, 73(2), 69–82.
- 37. Stensel, D. (2011, February). Exercise, appetite and appetite-regulating hormones: Implications for food
intake and weight control. Annals of Nutrition and Metabolism, Vol. 57, pp. 36–42.
- 38. Thom, G., Dombrowski, S. U., Brosnahan, N., Algindan, Y. Y., Rosario Lopez-Gonzalez, M., Roditi, G., …
Malkova, D. (2020). The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and
stress in long-term weight-loss maintenance: a mixed-methods study. European Journal of Clinical
Nutrition, 74(4), 622–632.
- 39. Austin, J., & Marks, D. (2009). Hormonal Regulators of Appetite. International Journal of Pediatric
Endocrinology, 9.
- 40. Palmer, M. A., Capra, S., & Baines, S. K. (2009, July). Association between eating frequency, weight, and
health. Nutrition Reviews, Vol. 67, pp. 379–390.
- 41. Vilela, S., Severo, M., Moreira, T., Oliveira, A., Hetherington, M. M., & Lopes, C. (2019). Association between
eating frequency and eating behaviours related to appetite from 4 to 7 years of age: Findings from the
population-based birth cohort generation XXI. Appetite, 132, 82–90.
- 42. Feinle-Bisset, C. (2014). Modulation of hunger and satiety: Hormones and diet. Current Opinion in Clinical
Nutrition and Metabolic Care, Vol. 17, pp. 458–464.
- 43. Perry, B., & Wang, Y. (2012). Appetite regulation and weight control: The role of gut hormones. Nutrition
and Diabetes, Vol. 2, pp. e26–e26.
- 44. Leidy, H. J., Armstrong, C. L. H., Tang, M., Mattes, R. D., & Campbell, W. W. (2010). The influence of higher
protein intake and greater eating frequency on appetite control in overweight and obese men. Obesity,
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