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Fabrication of Bioactive High Porous Hydroxyapatite Ceramics

Year 2015, Volume: 3 Issue: 2, 8 - 13, 14.11.2015
https://doi.org/10.5505/apjes.2015.14622

Abstract

The main subject of this study was to produce a net shaped micro porous hydroxyapatite ceramics. For this aim, initially fabrication of hydroxyapatite powder was achieved by a thermal extraction method which is inexpensive processing route. Phase determination of the yield of the process was carried out by X-ray diffraction method. Replica technique was used to produce a reticulated structure from hydroxyapatite powder. The foams were produced with various rates of additive as binder and additive-free compositions. After the HAp daubed on surfaces of substrate polymer was fired and sintered in the process at > 1100°C. The obtained ceramic foam was characterized using optical microscopy. The preform exhibited different pore sized structures depending binder rate and sintering temperature. As a result, hydroxyapatite preforms were produced with high porosity and their properties were improved by adding the binder which supports biocompability of HAp.

References

  • [1] Weng, W., and Baptista, J. L., A New Synthesis of Hydroxyapatite, Journal of the European Ceramic Society, 17, 1151-1156, 1997.
  • [2] Vallet-Regi M., Rodriguez-Lorenzo L.M., Salinas A.J., Synthesis and characterisation of calcium deficient apatite, Solid State Ionics 101- 103 (1997) 1279-1285
  • [3] Sanden, B., Olerud, C., Petren-Mallmin, M., Larsson, S., 2002. Hydroxtapatite coating improves fixation of pedicle screws. The jour. of bone & joint surgery (Br), vol. 84-B: 387-391, 2002.
  • [4] Tas, A.C. Combustion synthesis of calcium phosphate bioceramics powders, Journal of the European Ceramic Society 20, 2389-2394, 2000.
  • [5] Nakamura, T., Bioceramics in Orthopedic Surgery. Bioceramics. 9, 31-34, 1996.
  • [6] Hench LL. Bioceramics: from concept to clinic. J Am Ceram Soc. 1991;74(7):1487–510.
  • [7] Tirrell, M., Kokkoli, E., The role of surface science in bioengineer materials, California, 2001.
  • [8] H.S. Ryua, K.S. Honga, J.K. Leeb, D.J. Kim, J. H. Leed, Chang B. S., Lee D.H., Lee C. K., Chung S. S., Magnesia-doped HA/b-TCPceramics and evaluation of their Biocompatibility, Biomaterials 25 (2004) 393–401
  • [9] Chen, F., Wang, Z.C. and Lin, C.J., Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nanocomposite for use in biomedical materials.
  • Materials Letters 57, 858-861, 2002. [10] Feng, W., Li, M.S., Lu, Y.P. and Qi, Y.X., A simple sol-gel technique for preparing hydroxyapatite nanopowders. Materials Letters 59, 916-919, 2005.
  • [11] Vildan, W. M., Herliansyah M. K., Nuroho W. P. And Senjaya W., Characterization of sintered hydroxyapatite from bovine bone, Jurnal Mesin dan Industri, Vol 4, No 1, ISSN 1693-704X, Hal. 77-81, Januari 2007.
  • [12] Haberko K., Bucko M.M., Brzezinska M. J., Haberko, M., Mosgava, W., Panz,T., Pyda, A.,Natural Hydroxyapatite - Its behaviour during heat treatment. J. Eur. Cer. Soc., 537-542, 2006.
  • [13] F. N. Oktar, G. Göller, Sintering effects on mechanical properties of glass-reinforced hydroxyapatite composites, Ceramics International 28, 617–621, 2002.
  • [14] A. Herzog, U. Vogt, O. Kaczmarek, R. Klingner, K. Richter, H. Thoemen, Porous SiC ceramics derived from tailored wood-based fiber boards. J. Am. Ceram. Soc. 89, 1499–1503 (2006)
  • [15] J.H. Eom, Y.W. Kim, I.H. Song, H.D. Kim, Processing and properties of polysiloxane-derived porous silicon carbide ceramics using hollow microspheres as templates. J. Eur. Ceram. Soc. 28, 1361–1364 (2008)
  • [16] Y.W. Kim, S.H. Kim, I.H. Song, H.D. Kim, C.B. Park, Fabrication of open-cell. Microcellular silicon carbide ceramics by carbothermal reduction. J. Am. Ceram. Soc. 88, 2949–2951 (2005)

Gözenekli Biyoaktif Hidroksiapatit Seramiklerinin Üretimi

Year 2015, Volume: 3 Issue: 2, 8 - 13, 14.11.2015
https://doi.org/10.5505/apjes.2015.14622

Abstract

Bu çalışmanın ana konusu, ağ yapılı mikro poroz hidroksiapatit seramiklerinin üretidir. Bu amaçla, ilk olarak hidroksiapatit tozu ekonomik bir üretim prosesi olan termal ekstraksiyon yöntemiyle üretilmiştir. Proses ürünündeki faz dönüşümü X-ray kırınımı metoduyla belirlenmiştir. Hidroksiapatit tozundan ağ yapılı gözenekli malzeme üretmek için Replika tekniği kullanılmıştır. Seramik köpükler, bağlayıcı olarak çeşitli oranlarda katkılar kullanarak veya katkısız kompozisyonlar kullanılarak üretilmiştir. Yüzeylerine HA sıvanmış altlık polimer yakılıp peşinden 1100°C üzerindeki sıcaklıklarda sinterlenmiştir. Elde edilen seramik köpükler optic mikroskopla karakterize edilmiştir. Preformlar, sinterleme sıcaklığı ve bağlayıcı oranına bağlı olarak farklı gözenek büyüklüklü yapılar ortaya koymuştur. Sonuç olarak, hidroksiapatit köpükler, yüksek poroziteli olark üretilmiş ve HAp biyoaktivitesini destekleyen bir bağlayıcı ilavesiyle özellikleri geliştirmiştir.

References

  • [1] Weng, W., and Baptista, J. L., A New Synthesis of Hydroxyapatite, Journal of the European Ceramic Society, 17, 1151-1156, 1997.
  • [2] Vallet-Regi M., Rodriguez-Lorenzo L.M., Salinas A.J., Synthesis and characterisation of calcium deficient apatite, Solid State Ionics 101- 103 (1997) 1279-1285
  • [3] Sanden, B., Olerud, C., Petren-Mallmin, M., Larsson, S., 2002. Hydroxtapatite coating improves fixation of pedicle screws. The jour. of bone & joint surgery (Br), vol. 84-B: 387-391, 2002.
  • [4] Tas, A.C. Combustion synthesis of calcium phosphate bioceramics powders, Journal of the European Ceramic Society 20, 2389-2394, 2000.
  • [5] Nakamura, T., Bioceramics in Orthopedic Surgery. Bioceramics. 9, 31-34, 1996.
  • [6] Hench LL. Bioceramics: from concept to clinic. J Am Ceram Soc. 1991;74(7):1487–510.
  • [7] Tirrell, M., Kokkoli, E., The role of surface science in bioengineer materials, California, 2001.
  • [8] H.S. Ryua, K.S. Honga, J.K. Leeb, D.J. Kim, J. H. Leed, Chang B. S., Lee D.H., Lee C. K., Chung S. S., Magnesia-doped HA/b-TCPceramics and evaluation of their Biocompatibility, Biomaterials 25 (2004) 393–401
  • [9] Chen, F., Wang, Z.C. and Lin, C.J., Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nanocomposite for use in biomedical materials.
  • Materials Letters 57, 858-861, 2002. [10] Feng, W., Li, M.S., Lu, Y.P. and Qi, Y.X., A simple sol-gel technique for preparing hydroxyapatite nanopowders. Materials Letters 59, 916-919, 2005.
  • [11] Vildan, W. M., Herliansyah M. K., Nuroho W. P. And Senjaya W., Characterization of sintered hydroxyapatite from bovine bone, Jurnal Mesin dan Industri, Vol 4, No 1, ISSN 1693-704X, Hal. 77-81, Januari 2007.
  • [12] Haberko K., Bucko M.M., Brzezinska M. J., Haberko, M., Mosgava, W., Panz,T., Pyda, A.,Natural Hydroxyapatite - Its behaviour during heat treatment. J. Eur. Cer. Soc., 537-542, 2006.
  • [13] F. N. Oktar, G. Göller, Sintering effects on mechanical properties of glass-reinforced hydroxyapatite composites, Ceramics International 28, 617–621, 2002.
  • [14] A. Herzog, U. Vogt, O. Kaczmarek, R. Klingner, K. Richter, H. Thoemen, Porous SiC ceramics derived from tailored wood-based fiber boards. J. Am. Ceram. Soc. 89, 1499–1503 (2006)
  • [15] J.H. Eom, Y.W. Kim, I.H. Song, H.D. Kim, Processing and properties of polysiloxane-derived porous silicon carbide ceramics using hollow microspheres as templates. J. Eur. Ceram. Soc. 28, 1361–1364 (2008)
  • [16] Y.W. Kim, S.H. Kim, I.H. Song, H.D. Kim, C.B. Park, Fabrication of open-cell. Microcellular silicon carbide ceramics by carbothermal reduction. J. Am. Ceram. Soc. 88, 2949–2951 (2005)
There are 16 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Fatih Çalışkan This is me

Zafer Tatlı This is me

Ayça Sonkaya This is me

Publication Date November 14, 2015
Submission Date November 14, 2015
Published in Issue Year 2015 Volume: 3 Issue: 2

Cite

IEEE F. . Çalışkan, Z. . Tatlı, and A. . Sonkaya, “Gözenekli Biyoaktif Hidroksiapatit Seramiklerinin Üretimi”, APJES, vol. 3, no. 2, pp. 8–13, 2015, doi: 10.5505/apjes.2015.14622.