İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME

Mehmet Melih Ömezli; Ferhat Ayrancı; Damla Torul; Emine Örnek Akdoğan

doi:10.17567/ataunidfd.706825

İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME

Abstract

İlaca Bağlı Çene Kemiği Osteonekrozu: Bir Derleme İlaca Bağlı Çene Kemiği Osteonekrozu (MRONJ) bifosfonatlar yanında antiosteoklastik ve antianjiyojenik aktiviteye sahip ilaçların kullanımı sonucu ortaya çıkan, maksilla ve mandibulada nekrotik kemik varlığı ile karakterize bir komplikasyondur. Hem hekimler hem de hastalar için ciddi bir problem oluşturan bu özgün komplikasyonun optimum düzeyde yönetimini sağlayarak hastaların ekonomik ve sosyal mağduriyetlerini önleyecek tedavi protokolü ile ilgili bir fikir birliği bulunmamaktadır. Bu derlemenin amacı ilaca bağlı çene kemiği osteonekrozunun etyopatolojisi ve güncel tedavi stratejilerini literatür ışığında sunmaktır. Anahtar kelimeler: osteonekroz, bifosfonat, denosumab, bevacizumab Medication Related Osteonecrosis of the Jawbones: A Review ABSTRACT Medication Related Osteonecrosis of the Jawbones: A Review Medication Related Osteonecrosis of the Jaws (MRONJ) is a complication characterized by the appearance of necrotic bone in the maxilla and mandible, resulting from the use of bisphosphonates as well as drugs with antiosteoclastic and antiangiogenic activity. No consensus has been reach regarding the treatment protocol that will prevent the economic and social burden of the patients by providing optimum management of this unique complication which constitutes a serious problem for both physicians and patients. The aim of this review is to present the etiopathology and current treatment strategies of Medication Related Osteonecrosis of the Jaws in the light of the literature. Keywords: osteonecrosis, bisphosphonate, denosumab, bevacizumab

Keywords

References

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Details

Primary Language

Turkish

Subjects

Dentistry

Journal Section

Review

Authors

Mehmet Melih Ömezli This is me
0000-0002-6606-6593
Andorra

Ferhat Ayrancı This is me
0000-0001-7126-5696
Andorra

Damla Torul This is me
0000-0003-2323-606X
Andorra

Emine Örnek Akdoğan This is me
0000-0002-0701-1103
Andorra

Publication Date

January 15, 2021

Submission Date

November 14, 2019

Acceptance Date

March 20, 2020

Published in Issue

Year 2021 Volume: 31 Number: 1

DOI

https://doi.org/10.17567/ataunidfd.706825

IZ

https://izlik.org/JA43MC37ES

Cite

RIS / Bibtex

APA

Ömezli, M. M., Ayrancı, F., Torul, D., & Örnek Akdoğan, E. (2021). İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 31(1), 115-123. https://doi.org/10.17567/ataunidfd.706825

AMA

1.Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2021;31(1):115-123. doi:10.17567/ataunidfd.706825

Chicago

Ömezli, Mehmet Melih, Ferhat Ayrancı, Damla Torul, and Emine Örnek Akdoğan. 2021. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 (1): 115-23. https://doi.org/10.17567/ataunidfd.706825.

EndNote

Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E (January 1, 2021) İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 1 115–123.

IEEE

[1]M. M. Ömezli, F. Ayrancı, D. Torul, and E. Örnek Akdoğan, “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”, Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, vol. 31, no. 1, pp. 115–123, Jan. 2021, doi: 10.17567/ataunidfd.706825.

ISNAD

Ömezli, Mehmet Melih - Ayrancı, Ferhat - Torul, Damla - Örnek Akdoğan, Emine. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31/1 (January 1, 2021): 115-123. https://doi.org/10.17567/ataunidfd.706825.

JAMA

1.Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2021;31:115–123.

MLA

Ömezli, Mehmet Melih, et al. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, vol. 31, no. 1, Jan. 2021, pp. 115-23, doi:10.17567/ataunidfd.706825.

Vancouver

1.Mehmet Melih Ömezli, Ferhat Ayrancı, Damla Torul, Emine Örnek Akdoğan. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2021 Jan. 1;31(1):115-23. doi:10.17567/ataunidfd.706825