İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME

Mehmet Melih Ömezli; Ferhat Ayrancı; Damla Torul; Emine Örnek Akdoğan

doi:10.17567/ataunidfd.706825

İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME

Öz

İlaca Bağlı Çene Kemiği Osteonekrozu: Bir Derleme İlaca Bağlı Çene Kemiği Osteonekrozu (MRONJ) bifosfonatlar yanında antiosteoklastik ve antianjiyojenik aktiviteye sahip ilaçların kullanımı sonucu ortaya çıkan, maksilla ve mandibulada nekrotik kemik varlığı ile karakterize bir komplikasyondur. Hem hekimler hem de hastalar için ciddi bir problem oluşturan bu özgün komplikasyonun optimum düzeyde yönetimini sağlayarak hastaların ekonomik ve sosyal mağduriyetlerini önleyecek tedavi protokolü ile ilgili bir fikir birliği bulunmamaktadır. Bu derlemenin amacı ilaca bağlı çene kemiği osteonekrozunun etyopatolojisi ve güncel tedavi stratejilerini literatür ışığında sunmaktır. Anahtar kelimeler: osteonekroz, bifosfonat, denosumab, bevacizumab Medication Related Osteonecrosis of the Jawbones: A Review ABSTRACT Medication Related Osteonecrosis of the Jawbones: A Review Medication Related Osteonecrosis of the Jaws (MRONJ) is a complication characterized by the appearance of necrotic bone in the maxilla and mandible, resulting from the use of bisphosphonates as well as drugs with antiosteoclastic and antiangiogenic activity. No consensus has been reach regarding the treatment protocol that will prevent the economic and social burden of the patients by providing optimum management of this unique complication which constitutes a serious problem for both physicians and patients. The aim of this review is to present the etiopathology and current treatment strategies of Medication Related Osteonecrosis of the Jaws in the light of the literature. Keywords: osteonecrosis, bisphosphonate, denosumab, bevacizumab

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Diş Hekimliği

Bölüm

Derleme

Yazarlar

Mehmet Melih Ömezli Bu kişi benim
0000-0002-6606-6593
Andorra

Ferhat Ayrancı Bu kişi benim
0000-0001-7126-5696
Andorra

Damla Torul Bu kişi benim
0000-0003-2323-606X
Andorra

Emine Örnek Akdoğan Bu kişi benim
0000-0002-0701-1103
Andorra

Yayımlanma Tarihi

15 Ocak 2021

Gönderilme Tarihi

14 Kasım 2019

Kabul Tarihi

20 Mart 2020

Yayımlandığı Sayı

Yıl 2021 Cilt: 31 Sayı: 1

DOI

https://doi.org/10.17567/ataunidfd.706825

IZ

https://izlik.org/JA43MC37ES

Kaynak Göster

RIS / Bibtex

APA

Ömezli, M. M., Ayrancı, F., Torul, D., & Örnek Akdoğan, E. (2021). İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 31(1), 115-123. https://doi.org/10.17567/ataunidfd.706825

AMA

1.Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Ata Diş Hek Fak Derg. 2021;31(1):115-123. doi:10.17567/ataunidfd.706825

Chicago

Ömezli, Mehmet Melih, Ferhat Ayrancı, Damla Torul, ve Emine Örnek Akdoğan. 2021. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 (1): 115-23. https://doi.org/10.17567/ataunidfd.706825.

EndNote

Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E (01 Ocak 2021) İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 1 115–123.

IEEE

[1]M. M. Ömezli, F. Ayrancı, D. Torul, ve E. Örnek Akdoğan, “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”, Ata Diş Hek Fak Derg, c. 31, sy 1, ss. 115–123, Oca. 2021, doi: 10.17567/ataunidfd.706825.

ISNAD

Ömezli, Mehmet Melih - Ayrancı, Ferhat - Torul, Damla - Örnek Akdoğan, Emine. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31/1 (01 Ocak 2021): 115-123. https://doi.org/10.17567/ataunidfd.706825.

JAMA

1.Ömezli MM, Ayrancı F, Torul D, Örnek Akdoğan E. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Ata Diş Hek Fak Derg. 2021;31:115–123.

MLA

Ömezli, Mehmet Melih, vd. “İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, c. 31, sy 1, Ocak 2021, ss. 115-23, doi:10.17567/ataunidfd.706825.

Vancouver

1.Mehmet Melih Ömezli, Ferhat Ayrancı, Damla Torul, Emine Örnek Akdoğan. İLACA BAĞLI ÇENE KEMİĞİ OSTEONEKROZU: BİR DERLEME. Ata Diş Hek Fak Derg. 01 Ocak 2021;31(1):115-23. doi:10.17567/ataunidfd.706825