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Ozone And Its Usage In Dentistry

Year 2013, Volume: 23 Issue: 1, 116 - 122, 01.01.2013

Arş. Gör. Zeynep Yeğin Doç. Dr. Gül Tosun

Abstract

The aim of modern dentistry is development of preventive approaches non-invasive techniques instead of invasive techniques in the treatment of dental caries to avoid unnecessary loss of substance. Currently accepted treatment approach is the early diagnosis of caries, to arrest the progression of established lesions and to enhance the natural process of lesion repair by remineralization. One of the protective and preventive approaches used for this purpose is ozone (O3) application. For many years, ozone is widely used in medicine because of strong anti-oxidant effect and powerful antimicrobial agent also used in dentistry in recent years. The aim of this review is to introduce the ozone and give information about the use of various areas in dentistry.

Keywords

Ozone; Dentistry

References

  • Bocci V. Does ozone therapy normalize the cellular redox balance? Implications for therapy of human immunodeficiency virus infection and several other diseases. Med Hypotheses 1996;46:150-4.
  • Edward L. Ozone: The revolution in dentistry. Quintessence Publishing Co. Ltd. London, 2004.
  • Baysan A, Whiley RA, Lynch E. Antimicrobial effect of a novel ozone- generating device on microorganisms associated with primary root carious lesions in vitro. Caries Res 2000;34:498-3.
  • Seidler V, Linetskiy I, Hubálková H, Staňková H, Šmucler R, Mazánek J. Ozone and ıts usage in general medicine and dentistry a review article. Prague Medical Report 2008;109:1:5–13.
  • Baysan A, Beighton D. Assessment of the ozonemediated killing of bacteria in infected dentine associated with non-cavitated occlusal carious lesions. Caries Res 2007;41:337-41.
  • Azarpazhooh A, Limeback H. The application of ozone in dentistry: a systematic review of literature. J Dent. 2008;36:104-16.
  • Grootveld M, Silwood CJ, Lynch E. High resolution 1H NMR investigations of the oxidative consumption of salivary biomolecules by ozone: relevance to the therapeutic applications of this agent in clinical dentistry. Biofactors 2006;27:5-18.
  • Maslennikov O, Kontorshchikova C, Gribkova I. Ozone Therapy In Practice. Nizhny Novgorod Rusya. 2008.
  • Güzel Ö, Yıldar E, Erdikmen DO. Medikal Ozon ve Veteriner Cerrahide Kullanımı. İstanbul Üniv Vet Fak Derg 2011;37:177-84.
  • Bocci V. Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today. J Biol Regul Homeost Agents 1996;10:31-53.
  • Pryor WA, Uppu RM. Akinetic model for the competitive reaction of ozone with amino acid residues in proteins in reverse micelles. J Biol Chem 1993;268:3120-6.
  • Legnani PP, Leoni E, Baraldi M, Pinelli G, Bisbini P. Evaluation of disinfection treatment systems for municipal waste water reclamation and reuse. Zentralbl Hyg Umweltmed 1996;98:552-66.
  • Özler M, Öter Ş, Korkmaz A. Ozon Gazının Tıbbi Amaçlı Kullanılması. TAF Prev Med Bull 2009;8:59
  • Bocci VA. Can ozonetherapy be performed if the biochemistry of the process cannot be controlled? Arch Med Res 2007;38:584-5.
  • Bocci VA. Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res 2006;37:425-35.
  • Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18month trial. Gerodontology 2003;20:106-220.
  • Babacan A. Ozon, Ozonterapi ve Klinik Kullanımı. Turkiye Klinikleri J Med Sci 2008;28:245-7.
  • Bezirtzoglou E, Cretoiu SM, Moldoveanu M, Alexopoulos A, Lazar V, Nakou M. A quantitative approach to the effectiveness of ozone against microbiota organisms colonizing toothbrushes. J Dent 2008;36:600-5.
  • Garg R, Tandon S. Ozone: A new face of dentistry. The Internet Journal of Dental Science 2009;7:2.
  • Nogales CG, Ferrari PH, Kantorovich EO, LageMarques JL. Ozone therapy in medicine and dentistry. J Contemp Dent Pract 2008;9:75-84.
  • Mosallam RS, Nemat A, El-Hoshy A, Suzuki S. Effect of oleozon on healing of exposed pulp tissues. Journal of American Science 2011;7:38-44. Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M et al. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiol Immunol 2005;20:206-10.
  • Murakami H, Mizuguchi M, Hattori M, Ito Y, Kawai T, Hasegawa J. Effect of denture cleaner using ozone against methicillin-resistant Staphylococcus aureus and E. coli T1 phage. Dent Mater J 2002;21:53-60.
  • Oizumi M, Suzuki T, Uchida M, Furuya J, Okamoto Y. In vitro testing of a denture cleaning method using ozone. J Med Dent Sci 1998;45:135-139.
  • Stübinger S, Sader R, Filippi A. The use of ozone in dentistry and maxillofacial surgery: a review. Quintessence Int 2006;37:353-9.
  • Filippi A. The influence of ozonised water on the epithelial wound healing process in the oral cavity. Deutsche Zahnärztliche Zeitschrift 1997;56:104-8. Guerra OC, Cepero SM, Jordán MEM, Vázquez TC. Aplicación de la ozonoterapia en el tratamiento de la alveolitis. Rev Cubana Estomatol 1997;34:21-4. Filippi A. Ozone in oral surgery - Current status and prospects. Ozone Science & Engineering 1997;19:387-93.
  • Burdurlu Ç, Delilbaşı Ç, Deniz E, Arslan A. Mandibüler gömülü üçüncü molar cerrahisi sonrası topikal ozon ve klorheksidin uygulamasının alveolit ve yara enfeksiyonu üzerine etkilerinin araştırılması. Turkiye Klinikleri J Dental Sci 2011;17:17-23.
  • Guinesi AS, Andolfatto C, Bonetti Filho I, Cardoso AA, Passaretti Filho J, Farac RV. Ozonized oils: a qualitative and quantitative analysis. Braz Dent J 2011;22:37-40.
  • Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiol Immunol 2004;19:240-6.
  • Estrela C, Estrela CRA, Decurcio DA, Hollanda ACB, Silva JA. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. Int Endod J 2007;40:85-93.
  • Good M, El Karim IA, Hussey DL. Endodontic ‘solutions’ part 1: a literature review on the use of endodontic lubricants, irrigants and medicaments. Dent Update 2012;39:239-46.
  • Restaino L, Frampton EW, Hemphill JB, Palnikar P. Efficacy of ozonated water against various foodrelated microorganisms. Applied And Environmental Microbiology 1995;Sept:3471–75.
  • Paraskeva P, Graham NJD. Ozonation of municipial wastewater effluents. Water Environment Research 2002;74:6:569-81.
  • Bezrukova IV, Petrukhina NB, Voinov PA. Experience in medical ozone use for root canal treatment. Stomatologiia (Mosk) 2005;84:20-2.
  • Karapetian VE, Lowden E, Zöller JE. Die Verwendung von Ozon in der Periimplantitis therapie - Klinische Studie. ZWR (The Use of Ozone in Periimplantitis-Treatment)– Das Deutsche Zahnärzteblatt 2007;116:214-8.
  • Brauner A. Clinical investigation of the therapeutic success of ozonized water for gingivitis and periodontitis (in German) Zahna¨rztl Praxis 1991;2:48–50.
  • Dhingra K, Vandana KL. Management of gingival inflammation in orthodontic patients with ozonated water irrigation – a pilot study. Int J Dent Hygiene 2011;9:296–302.
  • Knezevic A, Tarle Z, Mandic V, Prskalo K, Panduric V, Jankovic B. Primary fissure carious lesion reversal using ozone. Acta Stomatol Croat 2007;41:31-8.
  • Baysan A, Lynch E, Grootveld M. The use of ozon efor the management of primary root carious lesions. Tissue Preservation and Caries Treatment. Quintessence Book 2001;3:49-67.
  • Abu-Naba’a L, Al Shorman H, Lynch E. Ozone Treatment of Primary Occlusal Pit and Fissure Caries: 12-Month Electrical Impedance Results and Clinical Implications Caries Res 2003;37:272-3.
  • Eligüzeloğlu E, Özcan S, Üçtaşlı MB, Ömürlü H. Kök Çürükleri ve Tedavileri. Atatürk Üniversitesi Diş Hek Derg 2007;17:32-8.
  • Polydorou O, Pelz K, Hahn P. Antibacterial effect of an ozone device and its comparison with two dentin-bonding systems. Eur J Oral Sci 2006; 114:349-53.
  • Burke FJ. Ozone and caries: a review of the literature. Dent Update 2012 May;39:271-2, 275-8. Elsalawy RN, Hamza HS, Yousry MM. The effectıveness of ozone gas as a bleachıng agent and ıts ınfluence on the enamel surface roughness. Egyptian Dental Journal 2005;51:1351.
  • Elhamid MA, Mosallam R. Effect of bleaching versus repolishing on colour and surface topography of stained resin composite. Australian Dental Journal 2010;55:390–8.
  • Filippi A. Water disinfection of dental units using ozone - Microbiological results after 11 years and technical problems. Ozone Sci Eng 2002;24:479
  • Walker JT, Bradshaw DJ, Fulford MR, Marsh PD. Microbiological evaluation of a range of disinfectant products to control mixed-species biofilm contamination in a laboratory model of a dental unit water system. Applied and Environmental Microbiology 2003;June:3327–32.
  • Das S. Application of Ozone Therapy in Dentistry. IJDA 2011;3:538-42.
  • Bocci, V. Is it true that ozone is always toxic? The end of a dogma. Toxicology and Applied Pharmacology 2006;216: 493-504.
  • Bocci V, Aldinucci C. Biochemical modifications induced in human blood by oxygenation-ozonation. J Biochem Mol Toxicol 2006;20:133-41.
  • Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R et al. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci 2006;114:435-40.
  • Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T, Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endod 2004;30:778-81.
  • Lynch E. Comment on "The application of ozone in dentistry: A systematic review of the literature". J Dent. 2009;37:406-10; author reply 411-2.
  • Loncar M, Stipetic D, Matosevic Z. Ozone Application in Dentistry. Archives of Medical Research 2009;40:136-7. Yazışma Adresi: Arş. Gör. Zeynep YEGİN
  • Selçuk Üniversitesi, Diş Hekimliği Fakültesi Pedodonti ABD, 42079. Konya, Türkiye. Tel: 0332 223 1290 - 0505 724 33 27 Faks: 0332 2410062
  • E-mail: zeynepygn@gmail.com

Diş Hekimliğinde Ozon ve Kullanım Alanları

Year 2013, Volume: 23 Issue: 1, 116 - 122, 01.01.2013

Arş. Gör. Zeynep Yeğin Doç. Dr. Gül Tosun

Abstract

Modern diş hekimliğinin amacı, diş çürüklerinin tedavisinde gereksiz madde kaybını önlemek amacıyla invaziv tedavi tekniklerinden çok non-invaziv ve koruyucu yaklaşımların geliştirilmesidir. Günümüzde kabul edilen tedavi yaklaşımı, çürüklerin erken teşhis edilebilmesi, ilerlemesinin önlenebilmesi ve remineralizasyonun sağlanabilmesidir. Bu amaçla kullanılan koruyucu ve önleyici yaklaşımlardan biri de ozon (O) uygulamasıdır. Uzun yıllardır güçlü antioksidan etkisinden dolayı tıpta geniş kullanım alanı bulan ozon, son yıllarda diş hekimliğinde de kullanılan güçlü bir antimikrobiyal ajandır. Bu derlemenin amacı ozonun tanıtılması ve diş hekimliğinde çeşitli alanlarda kullanımı hakkında bilgi vermektir.

Keywords

Ozon; Diş Hekimliği

References

  • Bocci V. Does ozone therapy normalize the cellular redox balance? Implications for therapy of human immunodeficiency virus infection and several other diseases. Med Hypotheses 1996;46:150-4.
  • Edward L. Ozone: The revolution in dentistry. Quintessence Publishing Co. Ltd. London, 2004.
  • Baysan A, Whiley RA, Lynch E. Antimicrobial effect of a novel ozone- generating device on microorganisms associated with primary root carious lesions in vitro. Caries Res 2000;34:498-3.
  • Seidler V, Linetskiy I, Hubálková H, Staňková H, Šmucler R, Mazánek J. Ozone and ıts usage in general medicine and dentistry a review article. Prague Medical Report 2008;109:1:5–13.
  • Baysan A, Beighton D. Assessment of the ozonemediated killing of bacteria in infected dentine associated with non-cavitated occlusal carious lesions. Caries Res 2007;41:337-41.
  • Azarpazhooh A, Limeback H. The application of ozone in dentistry: a systematic review of literature. J Dent. 2008;36:104-16.
  • Grootveld M, Silwood CJ, Lynch E. High resolution 1H NMR investigations of the oxidative consumption of salivary biomolecules by ozone: relevance to the therapeutic applications of this agent in clinical dentistry. Biofactors 2006;27:5-18.
  • Maslennikov O, Kontorshchikova C, Gribkova I. Ozone Therapy In Practice. Nizhny Novgorod Rusya. 2008.
  • Güzel Ö, Yıldar E, Erdikmen DO. Medikal Ozon ve Veteriner Cerrahide Kullanımı. İstanbul Üniv Vet Fak Derg 2011;37:177-84.
  • Bocci V. Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today. J Biol Regul Homeost Agents 1996;10:31-53.
  • Pryor WA, Uppu RM. Akinetic model for the competitive reaction of ozone with amino acid residues in proteins in reverse micelles. J Biol Chem 1993;268:3120-6.
  • Legnani PP, Leoni E, Baraldi M, Pinelli G, Bisbini P. Evaluation of disinfection treatment systems for municipal waste water reclamation and reuse. Zentralbl Hyg Umweltmed 1996;98:552-66.
  • Özler M, Öter Ş, Korkmaz A. Ozon Gazının Tıbbi Amaçlı Kullanılması. TAF Prev Med Bull 2009;8:59
  • Bocci VA. Can ozonetherapy be performed if the biochemistry of the process cannot be controlled? Arch Med Res 2007;38:584-5.
  • Bocci VA. Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res 2006;37:425-35.
  • Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18month trial. Gerodontology 2003;20:106-220.
  • Babacan A. Ozon, Ozonterapi ve Klinik Kullanımı. Turkiye Klinikleri J Med Sci 2008;28:245-7.
  • Bezirtzoglou E, Cretoiu SM, Moldoveanu M, Alexopoulos A, Lazar V, Nakou M. A quantitative approach to the effectiveness of ozone against microbiota organisms colonizing toothbrushes. J Dent 2008;36:600-5.
  • Garg R, Tandon S. Ozone: A new face of dentistry. The Internet Journal of Dental Science 2009;7:2.
  • Nogales CG, Ferrari PH, Kantorovich EO, LageMarques JL. Ozone therapy in medicine and dentistry. J Contemp Dent Pract 2008;9:75-84.
  • Mosallam RS, Nemat A, El-Hoshy A, Suzuki S. Effect of oleozon on healing of exposed pulp tissues. Journal of American Science 2011;7:38-44. Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M et al. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiol Immunol 2005;20:206-10.
  • Murakami H, Mizuguchi M, Hattori M, Ito Y, Kawai T, Hasegawa J. Effect of denture cleaner using ozone against methicillin-resistant Staphylococcus aureus and E. coli T1 phage. Dent Mater J 2002;21:53-60.
  • Oizumi M, Suzuki T, Uchida M, Furuya J, Okamoto Y. In vitro testing of a denture cleaning method using ozone. J Med Dent Sci 1998;45:135-139.
  • Stübinger S, Sader R, Filippi A. The use of ozone in dentistry and maxillofacial surgery: a review. Quintessence Int 2006;37:353-9.
  • Filippi A. The influence of ozonised water on the epithelial wound healing process in the oral cavity. Deutsche Zahnärztliche Zeitschrift 1997;56:104-8. Guerra OC, Cepero SM, Jordán MEM, Vázquez TC. Aplicación de la ozonoterapia en el tratamiento de la alveolitis. Rev Cubana Estomatol 1997;34:21-4. Filippi A. Ozone in oral surgery - Current status and prospects. Ozone Science & Engineering 1997;19:387-93.
  • Burdurlu Ç, Delilbaşı Ç, Deniz E, Arslan A. Mandibüler gömülü üçüncü molar cerrahisi sonrası topikal ozon ve klorheksidin uygulamasının alveolit ve yara enfeksiyonu üzerine etkilerinin araştırılması. Turkiye Klinikleri J Dental Sci 2011;17:17-23.
  • Guinesi AS, Andolfatto C, Bonetti Filho I, Cardoso AA, Passaretti Filho J, Farac RV. Ozonized oils: a qualitative and quantitative analysis. Braz Dent J 2011;22:37-40.
  • Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiol Immunol 2004;19:240-6.
  • Estrela C, Estrela CRA, Decurcio DA, Hollanda ACB, Silva JA. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. Int Endod J 2007;40:85-93.
  • Good M, El Karim IA, Hussey DL. Endodontic ‘solutions’ part 1: a literature review on the use of endodontic lubricants, irrigants and medicaments. Dent Update 2012;39:239-46.
  • Restaino L, Frampton EW, Hemphill JB, Palnikar P. Efficacy of ozonated water against various foodrelated microorganisms. Applied And Environmental Microbiology 1995;Sept:3471–75.
  • Paraskeva P, Graham NJD. Ozonation of municipial wastewater effluents. Water Environment Research 2002;74:6:569-81.
  • Bezrukova IV, Petrukhina NB, Voinov PA. Experience in medical ozone use for root canal treatment. Stomatologiia (Mosk) 2005;84:20-2.
  • Karapetian VE, Lowden E, Zöller JE. Die Verwendung von Ozon in der Periimplantitis therapie - Klinische Studie. ZWR (The Use of Ozone in Periimplantitis-Treatment)– Das Deutsche Zahnärzteblatt 2007;116:214-8.
  • Brauner A. Clinical investigation of the therapeutic success of ozonized water for gingivitis and periodontitis (in German) Zahna¨rztl Praxis 1991;2:48–50.
  • Dhingra K, Vandana KL. Management of gingival inflammation in orthodontic patients with ozonated water irrigation – a pilot study. Int J Dent Hygiene 2011;9:296–302.
  • Knezevic A, Tarle Z, Mandic V, Prskalo K, Panduric V, Jankovic B. Primary fissure carious lesion reversal using ozone. Acta Stomatol Croat 2007;41:31-8.
  • Baysan A, Lynch E, Grootveld M. The use of ozon efor the management of primary root carious lesions. Tissue Preservation and Caries Treatment. Quintessence Book 2001;3:49-67.
  • Abu-Naba’a L, Al Shorman H, Lynch E. Ozone Treatment of Primary Occlusal Pit and Fissure Caries: 12-Month Electrical Impedance Results and Clinical Implications Caries Res 2003;37:272-3.
  • Eligüzeloğlu E, Özcan S, Üçtaşlı MB, Ömürlü H. Kök Çürükleri ve Tedavileri. Atatürk Üniversitesi Diş Hek Derg 2007;17:32-8.
  • Polydorou O, Pelz K, Hahn P. Antibacterial effect of an ozone device and its comparison with two dentin-bonding systems. Eur J Oral Sci 2006; 114:349-53.
  • Burke FJ. Ozone and caries: a review of the literature. Dent Update 2012 May;39:271-2, 275-8. Elsalawy RN, Hamza HS, Yousry MM. The effectıveness of ozone gas as a bleachıng agent and ıts ınfluence on the enamel surface roughness. Egyptian Dental Journal 2005;51:1351.
  • Elhamid MA, Mosallam R. Effect of bleaching versus repolishing on colour and surface topography of stained resin composite. Australian Dental Journal 2010;55:390–8.
  • Filippi A. Water disinfection of dental units using ozone - Microbiological results after 11 years and technical problems. Ozone Sci Eng 2002;24:479
  • Walker JT, Bradshaw DJ, Fulford MR, Marsh PD. Microbiological evaluation of a range of disinfectant products to control mixed-species biofilm contamination in a laboratory model of a dental unit water system. Applied and Environmental Microbiology 2003;June:3327–32.
  • Das S. Application of Ozone Therapy in Dentistry. IJDA 2011;3:538-42.
  • Bocci, V. Is it true that ozone is always toxic? The end of a dogma. Toxicology and Applied Pharmacology 2006;216: 493-504.
  • Bocci V, Aldinucci C. Biochemical modifications induced in human blood by oxygenation-ozonation. J Biochem Mol Toxicol 2006;20:133-41.
  • Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R et al. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci 2006;114:435-40.
  • Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T, Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endod 2004;30:778-81.
  • Lynch E. Comment on "The application of ozone in dentistry: A systematic review of the literature". J Dent. 2009;37:406-10; author reply 411-2.
  • Loncar M, Stipetic D, Matosevic Z. Ozone Application in Dentistry. Archives of Medical Research 2009;40:136-7. Yazışma Adresi: Arş. Gör. Zeynep YEGİN
  • Selçuk Üniversitesi, Diş Hekimliği Fakültesi Pedodonti ABD, 42079. Konya, Türkiye. Tel: 0332 223 1290 - 0505 724 33 27 Faks: 0332 2410062
  • E-mail: zeynepygn@gmail.com
There are 54 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Arş. Gör. Zeynep Yeğin This is me

Doç. Dr. Gül Tosun This is me

Publication Date January 1, 2013
Published in Issue Year 2013 Volume: 23 Issue: 1

Cite

APA Yeğin, A. G. Z., & Tosun, D. D. G. (2013). Diş Hekimliğinde Ozon ve Kullanım Alanları. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 23(1), 116-122.
AMA Yeğin AGZ, Tosun DDG. Diş Hekimliğinde Ozon ve Kullanım Alanları. Ata Diş Hek Fak Derg. January 2013;23(1):116-122.
Chicago Yeğin, Arş. Gör. Zeynep, and Doç. Dr. Gül Tosun. “Diş Hekimliğinde Ozon Ve Kullanım Alanları”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 23, no. 1 (January 2013): 116-22.
EndNote Yeğin AGZ, Tosun DDG (January 1, 2013) Diş Hekimliğinde Ozon ve Kullanım Alanları. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 23 1 116–122.
IEEE A. G. Z. Yeğin and D. D. G. Tosun, “Diş Hekimliğinde Ozon ve Kullanım Alanları”, Ata Diş Hek Fak Derg, vol. 23, no. 1, pp. 116–122, 2013.
ISNAD Yeğin, Arş. Gör. Zeynep - Tosun, Doç. Dr. Gül. “Diş Hekimliğinde Ozon Ve Kullanım Alanları”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 23/1 (January 2013), 116-122.
JAMA Yeğin AGZ, Tosun DDG. Diş Hekimliğinde Ozon ve Kullanım Alanları. Ata Diş Hek Fak Derg. 2013;23:116–122.
MLA Yeğin, Arş. Gör. Zeynep and Doç. Dr. Gül Tosun. “Diş Hekimliğinde Ozon Ve Kullanım Alanları”. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, vol. 23, no. 1, 2013, pp. 116-22.
Vancouver Yeğin AGZ, Tosun DDG. Diş Hekimliğinde Ozon ve Kullanım Alanları. Ata Diş Hek Fak Derg. 2013;23(1):116-22.

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