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PROSTAGLANDIN AMOUNT IN GASTROINTESTINAL JUICE IN PATIENTS WITH STOMACH AND DUODENAL ULCERS

Year 1981, Volume: 34 Issue: 1, 51 - 56, 11.08.1981

Abstract

In the gastric juice of duodenal ulcer patients GPE,- like activity Was İower than in controls. The difference was not statisticaly importent, Therefore orally used PG's should not beecpected to treat PG deficiency and hence duodenal ulcer. PGE,-like activity was higher in gastric ulcer patients when compared With duode- nal ulcer patients and control.

References

  • 1, Bennett A, Fleshler B : Prostaglandins and the gastrointestinal tract, Gastroenteroloji 12 790, 1970
  • 2. Bennett A, Murray JG, Wyllie JH : Occurrence of prostaglandin E2 in the human stomach and a study of its effect on human isolated muscle, Br J Pharm Chemo 32 339, 1968
  • 3. Bennett A, Stamford IF, Unger WG : Prostaglandin Ep and gastric acid secretion in amn, J Physi01 229 : 349, 1973
  • 4. Bennett A, Stamford IF, Unger WG : PGE2 and gastric acid secretion in man Adv Biosci, 9 : 265, 1973
  • 5. Chen F, H, Karim S : The effect of 15 (R) methyl prostaglandin Eg on gastric acid Secretion in duodenal ülcer patientiens, Prostagladins 13 : IIS, 1977
  • 6. Coeeani F ve ark : Effect of nerve stimulation on prostaglandin formation and release from the rat stomach Amer J Phys 213 : 1056, 1967
  • 7. Fung wp, Karim SMM, Tye CY : Effect of 15 (R) 15 methÿ prostaglandin E2 methl ester on healing of gastric ulcers, Lancet 2 : 10, 1974
  • 8. Fung WI', Lee SK, Karim SMM : Effect of prostaglandin 15 (R) 15 methyl-Eg metyl ester on the gastric mucosa in patiens with peptic ulceration. An endoscopis and his. tolojical study, Prostaglandins 5 : 465, 1974
  • 9. Hansson E, Sammuelson B : Autoradiographie distrubîtion studies of Ha-Labelled pros taglandin E in micç, Biochim Biophys Acta 106 379, 1965
  • 10, Hinsdale JG, Engel JJ, Wüson DE : Prostaglandin E in peptic ulcer dísease, Prostaglandins 6 : 495, 1974
  • 11. Horton EW,Ate ark : Effect of orall administered prostaglandin El on gastric secretion and gastrointestinal motility in man, Gut 9 655, 1968
  • 12. Nylander B, Anderson S : Effect of two methylated prostaglandin El analogs on duodenal pressure in man, Scan J Gastroenteroloji, 10 : 91, 1975 13. Robert A, Effect of prostaglandins on the stomach and intestine. Prostaglandins 6 : 523, 1974
  • 14. Sehultz AR, Nezamis JE, Lancaster C : Gastric antisecretory and antiulcer proporties of PGEp, 15-methyl PGE2 and 16, 16 dimethyl PGE2 intravenous oral and intrajejunal administration., Gastroenterology 70 : 359, 1976
  • 15. Tonnesen MG, ve ark Circadian variation of prostaglandin E(PGE) production in human gastric juice, Dig Dis 19 : 644, 1974
  • 16, Vane JR : A sensitive method for the assay of 5-dydroxtrltamine, Brit J Pharmacol 12 : 344, 1957
  • 17. Vane JR ; The use of isolated organs for detecting active substances in the circulating blood, Brit J Pharma 23 : 260, 1964
  • 18. Wilson DE, ve ark : Effect on an orally administered prostaglandin analogue (16,16-di methy prostagandin Ea) on human gastric secretion, Gastroenterology 69 : 607, 1975

Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı

Year 1981, Volume: 34 Issue: 1, 51 - 56, 11.08.1981

Abstract

Duodenum ülseri bulunan hastalarımızda mide suyundaki PGE.'ye benzer aktivite seviyeleri kontrol gurubuna göre düşük bulunmuştur, Ancak bu düşüklük istatistiki bakımdan anlamlı değildir. Bu nedenle oral kullanılan pristaglandin'in duodenum ülserlilerde PG yetersizliğini gidermek yoluyla etkili olması beklenemez, Mide ülseri bulunan hastalarda ise mide suyundaki PGE,'ye benzer aktivite kontrol ve duodenum ülserli hasta grubuna göre yüksek bulunmuştur.

References

  • 1, Bennett A, Fleshler B : Prostaglandins and the gastrointestinal tract, Gastroenteroloji 12 790, 1970
  • 2. Bennett A, Murray JG, Wyllie JH : Occurrence of prostaglandin E2 in the human stomach and a study of its effect on human isolated muscle, Br J Pharm Chemo 32 339, 1968
  • 3. Bennett A, Stamford IF, Unger WG : Prostaglandin Ep and gastric acid secretion in amn, J Physi01 229 : 349, 1973
  • 4. Bennett A, Stamford IF, Unger WG : PGE2 and gastric acid secretion in man Adv Biosci, 9 : 265, 1973
  • 5. Chen F, H, Karim S : The effect of 15 (R) methyl prostaglandin Eg on gastric acid Secretion in duodenal ülcer patientiens, Prostagladins 13 : IIS, 1977
  • 6. Coeeani F ve ark : Effect of nerve stimulation on prostaglandin formation and release from the rat stomach Amer J Phys 213 : 1056, 1967
  • 7. Fung wp, Karim SMM, Tye CY : Effect of 15 (R) 15 methÿ prostaglandin E2 methl ester on healing of gastric ulcers, Lancet 2 : 10, 1974
  • 8. Fung WI', Lee SK, Karim SMM : Effect of prostaglandin 15 (R) 15 methyl-Eg metyl ester on the gastric mucosa in patiens with peptic ulceration. An endoscopis and his. tolojical study, Prostaglandins 5 : 465, 1974
  • 9. Hansson E, Sammuelson B : Autoradiographie distrubîtion studies of Ha-Labelled pros taglandin E in micç, Biochim Biophys Acta 106 379, 1965
  • 10, Hinsdale JG, Engel JJ, Wüson DE : Prostaglandin E in peptic ulcer dísease, Prostaglandins 6 : 495, 1974
  • 11. Horton EW,Ate ark : Effect of orall administered prostaglandin El on gastric secretion and gastrointestinal motility in man, Gut 9 655, 1968
  • 12. Nylander B, Anderson S : Effect of two methylated prostaglandin El analogs on duodenal pressure in man, Scan J Gastroenteroloji, 10 : 91, 1975 13. Robert A, Effect of prostaglandins on the stomach and intestine. Prostaglandins 6 : 523, 1974
  • 14. Sehultz AR, Nezamis JE, Lancaster C : Gastric antisecretory and antiulcer proporties of PGEp, 15-methyl PGE2 and 16, 16 dimethyl PGE2 intravenous oral and intrajejunal administration., Gastroenterology 70 : 359, 1976
  • 15. Tonnesen MG, ve ark Circadian variation of prostaglandin E(PGE) production in human gastric juice, Dig Dis 19 : 644, 1974
  • 16, Vane JR : A sensitive method for the assay of 5-dydroxtrltamine, Brit J Pharmacol 12 : 344, 1957
  • 17. Vane JR ; The use of isolated organs for detecting active substances in the circulating blood, Brit J Pharma 23 : 260, 1964
  • 18. Wilson DE, ve ark : Effect on an orally administered prostaglandin analogue (16,16-di methy prostagandin Ea) on human gastric secretion, Gastroenterology 69 : 607, 1975
There are 17 citations in total.

Details

Primary Language Turkish
Subjects Gastroenterology Surgery
Journal Section Articles
Authors

Erdem Alptuna This is me

Publication Date August 11, 1981
Published in Issue Year 1981 Volume: 34 Issue: 1

Cite

APA Alptuna, E. (1981). Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 34(1), 51-56.
AMA Alptuna E. Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı. Ankara Üniversitesi Tıp Fakültesi Mecmuası. August 1981;34(1):51-56.
Chicago Alptuna, Erdem. “Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34, no. 1 (August 1981): 51-56.
EndNote Alptuna E (August 1, 1981) Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34 1 51–56.
IEEE E. Alptuna, “Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 1, pp. 51–56, 1981.
ISNAD Alptuna, Erdem. “Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 34/1 (August1981), 51-56.
JAMA Alptuna E. Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34:51–56.
MLA Alptuna, Erdem. “Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 34, no. 1, 1981, pp. 51-56.
Vancouver Alptuna E. Mide Ve Duedenum Ülseri Bulunan Hastalarda Mide Suyundaki Prostaglandin Miktarı. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1981;34(1):51-6.