Congenital Heart Disease in Down's Syndrome

Year 1979, Volume: 29 Issue: 4, 479 - 486, 31.12.1979

Ayten İmamoğlu

Abstract

Eighty Down Syndrome cases were examined in our Pediatrics Department. Between the years 1972-1978. Twenty six of them (32.5%) were diagnosed as having congenital heart disease. The ratio of girls to boys Was 10 : 16 respectively. Eight patients (27 %) died because of congestive heart failure and respiratory diseases. Among the congenital heart diseases, Endocordial Cushion Defect “had the highest prevalance 42.3% -11 of the 26 patients. Ventricular Septal Defect (9 cases-34.6 %), Atrial Septal Defect (3 cases-11.5 %), Tetralogy of Fallot (2 cases-7.7 %) and Patent Ductus Arteriosus (1 cases-3.8 %) were following this respectively. Early diagnosis and surgical treatment will decrease mortality rate in these patients.

Keywords

down syndrome , pediatrics , congenital heart diseases

Down Sendromunda Konjenital Kalp Hastalıkları

Abstract

1972 - 1978 yılları arasında kliniğimizde görülen 80 Down sendromu olgusundan 26'sında konjenital kalp hastalığı saptandı. Oran % 32.5 bulundu. Erkek- kız oranı 16/10 bulundu. Sekiz hasta (% 27) konjestif kalp yetmezliği ve akciğer hastalığı nedeni ile yitirildiler. Konjenital kalp hastalıkları arasında en olağan lezyon Endocardial Cushion Defect (11 olgu) % 42.3 olarak saptandı. Bunu sırası ile. ventriküler septal defekt (9 olgu) % 34.6, atrial septal defekt (3 olgu) % 11.5, Fallot tetralojisi (2 olgu) % 7.7 patent duktus arteriosus (1 olgu) % 3.8 izliyordu. Bizim araştırmamızdaki Down sendromu olgularında bulunan konjenital kalp hastalığı ve bunlar arasında major kalp lezyonlarının görülüş sıklığının literatürle uvgunluk gösterdiği saptandı. Erken cerrahi girişimin bu hastaların yaşamını uzatacağına dikkat çekildi.

Keywords

down sendromu , pediatri , konjenital kalp hastalıkları

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