Extended spectrum beta-lactamase activity and multidrug resistance of Salmonella serovars isolated from chicken carcasses from different regions of Turkey

Abstract

This research was conducted to investigate the extended spectrum beta-lactamase activity and multidrug resistance of Salmonella serovars isolated from chicken carcasses. For this purpose, 99 Salmonella isolates from 930 chicken carcasses were tested against 12 different antimicrobials. The resistance rates of Salmonella isolates to antimicrobials were as follows: 35.3% (35/99) to ampicillin, 33.3% (33/99) to tetracycline, 29.2% to amoxicillin-clavulanic acid, 18.1% (18/99) to nalidixic acid, 17.1% (17/99) to chloramphenicol, 16.1% (16/99) to aztreonam, 12.1% (12/99) to trimethoprim-sulfamethoxazole, 4% (4/99) to gentamicin, 1.0% (1/99) to ceftazidime. Of the isolates 46.4% (46/99) were found to be resistant to two or more antimicrobials as a multidrug resistance. Extended spectrum beta-lactamase activity was detected in 1.0% (1/99) of the isolates. Furthermore, S. Typhimurium 26.2% (28/99), S. Infantis 16.1% (16/99), S. Hadar 12.1% (10/99) and S. Branderburg 9.0% (9/99) were found to be the predominant serovars. In conclusion, antimicrobial resistance and also multidrug resistance rates of Salmonella isolates in this study, indicated that monitoring of antimicrobial resistance profiles is important for Salmonella infections to plan treatment strategies

Keywords

• Chicken carcass
• ESβLs
• Multidrug resistance
• Salmonella serovar

Türkiye’nin çeşitli bölgelerindeki tavuk karkaslarından izole edilen Salmonella seovarlarının çokluilaç dirençliliği ve geniş spektrumlu beta laktamaz aktivitesi

Abstract

Bu çalışma, tavuk karkaslarından izole edilen Salmonella serovarlarının çoklu ilaç dirençliliği ve geniş spektrumlu beta laktamaz aktivitesinin araştırılması amacıyla yürütülmüştür. Çalışmada, 930 tavuk karkasından izole edilen 99 Salmonella izolatı 12 farklı antimikrobiyale karşı test edilmiştir. Salmonella izolatlarının antimikrobiyallere karşı direnç oranları sırasıyla; ampisiline %35.3 (35/99), tetrasikline %33.3 (33/99), amoksisilin-clavulanic asite %29.2 (29/99), nalidiksik asite %18.1 (18/99), kloramfenikole %17.1 (17/99), aztreonama %16.1 (16/99), trimetoprim-sulfametoksazole %12.1 (12/99), gentamisine %4 (4/99), seftazidime %1.0 (1/99) olarak belirlenmiştir. İzolatların %46.4 (46/99)’ünün çoklu ilaç dirençli olarak iki veya daha fazla antibiyotiğe direnç gösterdiği tespit edilmiştir. Geniş spektrumlu beta laktamaz aktivitesi %1.0 (1/99) oranında bulunmuştur. Ayrıca, S. Typhimurium %26.2 (28/99), S. Infantis %16.1 (16/99), S. Hadar %12.1 (10/99) ve S. Branderburg %9.0 (9/99) çalışmadaki predominat serovarlardır. Sonuç olarak, antimikrobiyal direnç ve çoklu ilaç direnç oranları, direnç profillerinin monitorize edilmesinin Salmonella enfeksiyonlarının tedavi stratejilerinin planlanması için önemli olduğunu göstermiştir

Keywords

• Çoklu ilaç direnci
• GSBL
• Salmonella serovar
• Tavuk karkası

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