SCRAPIE

Abstract

Scrapie is a progressive disease of sheep characterised by nervous symptoms and by a diffuse or focal degeneration of the grey matter of the subcortical centers along the neuroaxis of the central nervous system. The disease as far as we are aware is invariably fataL. The clinical symptoms in the shcep consist of incoordination of gait, trembling and severe itch which causcs persistent rubing of parts of the body against various fixed objccts. In many cases one or more of the above symptoms may be cither, diminished or grossly exaggerated, (Fig. i and 2). . Apart from an obvious increase in the amount of the cerebrospinal fluid, all other pathological changes are microscopical and rcquirc for theİr identification histogical methods of examination. Lesions are most promincnt in the brain stern, especially in the medulla but are also present in all other parts of thG brain, such as the midbrain, thalamus, hypothalamus, paraterminal body and the cerebellum The spinal cord is also arkcted in a proportion of nature! cases, but no lesions are found as a rule in the cerebral haemispheres, cortex, hippocampus and amygdala (Zlotnik, 1957, 1958 I, 2 1960 and Zlotnik and Katiyar, 1961)

Keywords

• nervous
• septoms
• scrapie

References

1. Ankara Üniversitesi- Ankara Üniversitesi Veteriner Fakültesi Dergisi