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ACİL KONTRASEPSİYON

Year 2015, Volume: 4 Issue: 1, 55 - 59, 30.04.2012

Abstract


Acil kontrasepsiyon, korunmasız bir cinsel ilişki sonrası uygulanan kontraseptif metotdur, böylelikle düzenli bir kontrasepsiyon metodu değildir. Acil kontrasepsiyon için değişik yaklaşımlar mevcut olup bunların başlıcaları: mifepriston, ulipristal asetat ve levonorgestrel gibi ilaçlar veya rahim içi araçlardır. Bu derlemede sizlere acil kontrasepsiyon ile ilgili güncel bilgileri sunmayı amaçladım.


References

  • 1. Sedgh G, Singh S, Shah IH, Ahman E, Henshaw SK, Bankole A. Induced abortion: incidence and trends worldwide from 1995 to 2008. Lancet ,2012; 379(9816): 625–32.
  • 2. Batur P. Emergency contraception: separating fact from fiction. Cleve Clin J Med. 2012;79(11):771-6.
  • 3. Mosher WD, Jones J. Use of contraception in the United States: 1982-2008. Vital Health Stat 23. 2010;(29):1-44.
  • 4. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü (2009) Türkiye Nüfus ve Sağlık Araştırması, 2008. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, Sağlık Bakanlığı Ana Çocuk Sağlığı ve Aile Planlaması Genel Müdürlüğü, Başbakanlık Devlet Planlama Teşkilatı Müsteşarlığı ve TÜBİTAK, Ankara, Türkiye.
  • 5. Morris JM, Van Wagenen G. Compounds interfering with ovum implantation and development. 3. The role of estrogens. Am J Obstet Gynecol. 1966;96(6):804-15.
  • 6. Yuzpe AA, Lancee WJ. Ethynylestradiol and dl-norgestrel as a postcoital contraceptive. Fertil Steril, 1977;28(9):932–6.
  • 7. Lippes J, Malik T, Tatum HJ. The postcoital copper-T. Adv Plan Parent. 1976;11(1):24-9.
  • 8. Yuzpe AA, Thurlow HJ, Ramzy I., Leyshon L. Post coital contraception- a pilot study. J.Reprod Med,1974; 13:53-8.
  • 9. Trussell J, Raymond EG. Statistical evidence about the mechanism of action of theYuzpe regimen of emergency contraception. Obstet Gynecol, 1999; 93(5 Pt 2):872-6.
  • 10. World Health Organization Task Force on Post-ovulatory Methods for Fertility Regulation. Randomized controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Lancet, 1998; 352(9126):428–33.
  • 11. World Health Organization Task Force on Post-ovulatory Methods for Fertility Regulation. Comparison of three single doses of mifepristone as emergency contraception: a randomised trial. Lancet, 1999; 353(9154): 697–702.
  • 12. von Hertzen H, Piaggio G, Ding J, Chen J, Song S, Bártfai G, et al. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet, 2002; 360(9348): 1803–10.
  • 13. Hamoda H, Ashok PW, Stalder C, Flett GM, Kennedy E, Templeton A. A randomized trial of mifepristone (10 mg) and levonorgestrel for emergency contraception. Obstetrics and Gynecology, 2004; 104(6): 1307–13.
  • 14. Davidoff F, Trussell J. Plan B and the politics of doubt. JAMA, 2006;296(14):1775–8.
  • 15. Gemzell-Danielsson K, Marions L. Mechanisms of action of mifepristone and levonorgestrel when used for emergency contraception. Hum Reprod Update. 2004;10(4):341–348.
  • 16. Cleland K, Raymond E, Trussell J, Cheng L, Zhu H. Ectopic pregnancy and emergency contraceptive pills. A systematic review. Obstet Gynecol, 2010;115(6):1263–6.
  • 17. Alvarez F, Faundes A, Johansson E, Coutinho E. Blood levels of levonorgestrel in women following vaginal placement of contraceptive pills. Fertil Steril, 1983;40(1):120–3.
  • 18. Raymond EG, Goldberg A, Trussell J, Hays M, Roach E, Taylor D. Bleeding patterns after use of levonorgestrel emergency contraceptive pills. Contraception, 2006;73(4):376–81.
  • 19. Allen RH, Goldberg AB. Emergency contraception: a clinical review. Clin Obstet Gynecol. 2007;50(4):927-36.
  • 20. Grimes DA, Raymond EC. Scott Jones B. Emergency contraception over-the counter: the medical and legal imperatives. Obstet Gynecol,2001;98(1):151–5.
  • 21. The Practice Committee of theAmerican Society for Reproductive Medicine. Hormonal contraception: recent advances and controversies. Fertil Steril, 2004;82(2):520-6.
  • 22. Cheng L, Gülmezoglu AM, Piaggio G, Ezcurra E, Van Look PF. Interventions for emergency contraception. Cochrane Database Syst Rev. 2008;16;(2):CD001324.
  • 23. Glasier A. Emergency postcoital contraception. N Engl J Med, 1997;337(15):1058–1064.
  • 24. Gemzell-Danielsson K, Swahn ML, Svalander P, Bygdeman M.. Early luteal phase treatment with mifepristone (RU 486) for fertility regulation. Human Reproduction, 1993; 8(6): 870–3.
  • 25. Marions L, Gemzell Danielsson K, Swahn ML, Bygdeman M. Contraceptive efficacy of low doses of mifepristone. Fertility and Sterility, 1998; 70(5): 813–6.
  • 26. Cheng L, Che Y, Gülmezoglu AM. Interventions for emergency contraception. Cochrane Database Syst Rev. 2012 Aug 15;8:CD001324.
  • 27. Webb AMC, Russell J, Elstein M. Comparison of Yuzpe regimen, danazol, and mifepristone (RU486) in oral postcoital contraception. BMJ, 1992; 305(6859):927–31.
  • 28. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU486) compared with high dose estrogen and progestogen for emergency postcoital contraception. N Engl J Med, 1992; 327(15):1041–4.
  • 29. Fine P, Mathe H, Ginde S, Cullins V, Morfesis J, Gainer E. Ulipristal acetate taken 48-120 hours after intercourse for emergency contraception. Obstet Gynecol, 2010;115 (2 Pt 1):257–63.
  • 30. Richardson AR, Maltz FN. Ulipristal acetate: review of the efficacy and safety of a newly approved agent for emergency contraception. Clin Ther, 2012;34(1):24-36.
  • 31. Stratton P, Hartog B, Hajizadeh N, Piquion J, Sutherland D, Merino M, et al. A single mid-follicular dose of CDB-2914, a new antiprogestin, inhibits folliculogenesis and endometrial differentiation in normally cycling women. Hum Reprod, 2000;15(5):1092–9.
  • 32. Stratton P, Levens ED, Hartog B, Piquion J, Wei Q, Merino M, et al. Endometrial effects of a single early luteal dose of the selective progesterone receptor modülatör CDB-2914. Fertil Steril, 2010;93(6): 2035–41.
  • 33. Creinin MD, Schlaff W, Archer DF, Wan L, Frezieres R, Thomas M, et al. Progesterone receptor modulator for emergency contraception: a randomized controlled trial. Obstetrics and Gynecology, 2006; 108(5): 1089–97.
  • 34. Glasier AF, Cameron ST, Fine PM, Logan SJ, Casale W, Van Horn J, et al. Ulipristal acetate versus levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis. Lancet, 2010; 375(9714): 555–62.
  • 35. Fine P, Mathé H, Ginde S, Cullins V, Morfesis J, Gainer E. Ulipristal acetate taken 48–120 hours after intercourse for emergency contraception. Obstetrics and Gynecology, 2010; 115 (2 Pt 1): 257–63.
  • 36. US Food and Drug Administration. Ulipristal acetate: new drug review application 22-474. Center for Drug Evaluation and Research. 2009.
  • 37. Zhou L, Xiao B. Emergency contraception with Multiload Cu-375 SL IUD: a multicenter clinical trial. Contraception, 2001;64(2):107–112.
  • 38. Lalitkumar PG, Berger C, Gemzell-Danielsson K. Emergency contraception. Best Pract Res Clin Endocrinol Metab, 2013;27(1):91-101.
  • 39. Zhou L, Xiao B. Emergency contraception with multi-load cu-375 SL IUD: a multicenter clinical trial. Contraception, 2001;64(2):107–112.
  • 40. Liu L, Chen A. A comparative study of mifepristone with Cu-IUD for emergency contraception. Changzhi Med Coll. 2002;61:198–9.
  • 41. Askalani AH, Al-Senity AM, Al-Agizy HM, Salam HI, Al-Masry GI, El-Sadek SM. Evaluation of copper T-200 as a post-coital contraceptive. Egyp J Obstet Gynaecol, 1987;13:63–6.

EMERGENCY CONTRACEPTION

Year 2015, Volume: 4 Issue: 1, 55 - 59, 30.04.2012

Abstract


Emergency contraception is a type of contraceptive methods that is used after unprotected intercourse, thus, this is not a suitable method for regular contraception. There are different approaches for emergency contraception mainly; drugs such as mifepristone, ulipristal acetate and levonorgestrel, or intrauterine devices (IUDs). In this review I would like to present an updated knowledge about emergency contraception.


References

  • 1. Sedgh G, Singh S, Shah IH, Ahman E, Henshaw SK, Bankole A. Induced abortion: incidence and trends worldwide from 1995 to 2008. Lancet ,2012; 379(9816): 625–32.
  • 2. Batur P. Emergency contraception: separating fact from fiction. Cleve Clin J Med. 2012;79(11):771-6.
  • 3. Mosher WD, Jones J. Use of contraception in the United States: 1982-2008. Vital Health Stat 23. 2010;(29):1-44.
  • 4. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü (2009) Türkiye Nüfus ve Sağlık Araştırması, 2008. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, Sağlık Bakanlığı Ana Çocuk Sağlığı ve Aile Planlaması Genel Müdürlüğü, Başbakanlık Devlet Planlama Teşkilatı Müsteşarlığı ve TÜBİTAK, Ankara, Türkiye.
  • 5. Morris JM, Van Wagenen G. Compounds interfering with ovum implantation and development. 3. The role of estrogens. Am J Obstet Gynecol. 1966;96(6):804-15.
  • 6. Yuzpe AA, Lancee WJ. Ethynylestradiol and dl-norgestrel as a postcoital contraceptive. Fertil Steril, 1977;28(9):932–6.
  • 7. Lippes J, Malik T, Tatum HJ. The postcoital copper-T. Adv Plan Parent. 1976;11(1):24-9.
  • 8. Yuzpe AA, Thurlow HJ, Ramzy I., Leyshon L. Post coital contraception- a pilot study. J.Reprod Med,1974; 13:53-8.
  • 9. Trussell J, Raymond EG. Statistical evidence about the mechanism of action of theYuzpe regimen of emergency contraception. Obstet Gynecol, 1999; 93(5 Pt 2):872-6.
  • 10. World Health Organization Task Force on Post-ovulatory Methods for Fertility Regulation. Randomized controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Lancet, 1998; 352(9126):428–33.
  • 11. World Health Organization Task Force on Post-ovulatory Methods for Fertility Regulation. Comparison of three single doses of mifepristone as emergency contraception: a randomised trial. Lancet, 1999; 353(9154): 697–702.
  • 12. von Hertzen H, Piaggio G, Ding J, Chen J, Song S, Bártfai G, et al. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet, 2002; 360(9348): 1803–10.
  • 13. Hamoda H, Ashok PW, Stalder C, Flett GM, Kennedy E, Templeton A. A randomized trial of mifepristone (10 mg) and levonorgestrel for emergency contraception. Obstetrics and Gynecology, 2004; 104(6): 1307–13.
  • 14. Davidoff F, Trussell J. Plan B and the politics of doubt. JAMA, 2006;296(14):1775–8.
  • 15. Gemzell-Danielsson K, Marions L. Mechanisms of action of mifepristone and levonorgestrel when used for emergency contraception. Hum Reprod Update. 2004;10(4):341–348.
  • 16. Cleland K, Raymond E, Trussell J, Cheng L, Zhu H. Ectopic pregnancy and emergency contraceptive pills. A systematic review. Obstet Gynecol, 2010;115(6):1263–6.
  • 17. Alvarez F, Faundes A, Johansson E, Coutinho E. Blood levels of levonorgestrel in women following vaginal placement of contraceptive pills. Fertil Steril, 1983;40(1):120–3.
  • 18. Raymond EG, Goldberg A, Trussell J, Hays M, Roach E, Taylor D. Bleeding patterns after use of levonorgestrel emergency contraceptive pills. Contraception, 2006;73(4):376–81.
  • 19. Allen RH, Goldberg AB. Emergency contraception: a clinical review. Clin Obstet Gynecol. 2007;50(4):927-36.
  • 20. Grimes DA, Raymond EC. Scott Jones B. Emergency contraception over-the counter: the medical and legal imperatives. Obstet Gynecol,2001;98(1):151–5.
  • 21. The Practice Committee of theAmerican Society for Reproductive Medicine. Hormonal contraception: recent advances and controversies. Fertil Steril, 2004;82(2):520-6.
  • 22. Cheng L, Gülmezoglu AM, Piaggio G, Ezcurra E, Van Look PF. Interventions for emergency contraception. Cochrane Database Syst Rev. 2008;16;(2):CD001324.
  • 23. Glasier A. Emergency postcoital contraception. N Engl J Med, 1997;337(15):1058–1064.
  • 24. Gemzell-Danielsson K, Swahn ML, Svalander P, Bygdeman M.. Early luteal phase treatment with mifepristone (RU 486) for fertility regulation. Human Reproduction, 1993; 8(6): 870–3.
  • 25. Marions L, Gemzell Danielsson K, Swahn ML, Bygdeman M. Contraceptive efficacy of low doses of mifepristone. Fertility and Sterility, 1998; 70(5): 813–6.
  • 26. Cheng L, Che Y, Gülmezoglu AM. Interventions for emergency contraception. Cochrane Database Syst Rev. 2012 Aug 15;8:CD001324.
  • 27. Webb AMC, Russell J, Elstein M. Comparison of Yuzpe regimen, danazol, and mifepristone (RU486) in oral postcoital contraception. BMJ, 1992; 305(6859):927–31.
  • 28. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU486) compared with high dose estrogen and progestogen for emergency postcoital contraception. N Engl J Med, 1992; 327(15):1041–4.
  • 29. Fine P, Mathe H, Ginde S, Cullins V, Morfesis J, Gainer E. Ulipristal acetate taken 48-120 hours after intercourse for emergency contraception. Obstet Gynecol, 2010;115 (2 Pt 1):257–63.
  • 30. Richardson AR, Maltz FN. Ulipristal acetate: review of the efficacy and safety of a newly approved agent for emergency contraception. Clin Ther, 2012;34(1):24-36.
  • 31. Stratton P, Hartog B, Hajizadeh N, Piquion J, Sutherland D, Merino M, et al. A single mid-follicular dose of CDB-2914, a new antiprogestin, inhibits folliculogenesis and endometrial differentiation in normally cycling women. Hum Reprod, 2000;15(5):1092–9.
  • 32. Stratton P, Levens ED, Hartog B, Piquion J, Wei Q, Merino M, et al. Endometrial effects of a single early luteal dose of the selective progesterone receptor modülatör CDB-2914. Fertil Steril, 2010;93(6): 2035–41.
  • 33. Creinin MD, Schlaff W, Archer DF, Wan L, Frezieres R, Thomas M, et al. Progesterone receptor modulator for emergency contraception: a randomized controlled trial. Obstetrics and Gynecology, 2006; 108(5): 1089–97.
  • 34. Glasier AF, Cameron ST, Fine PM, Logan SJ, Casale W, Van Horn J, et al. Ulipristal acetate versus levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis. Lancet, 2010; 375(9714): 555–62.
  • 35. Fine P, Mathé H, Ginde S, Cullins V, Morfesis J, Gainer E. Ulipristal acetate taken 48–120 hours after intercourse for emergency contraception. Obstetrics and Gynecology, 2010; 115 (2 Pt 1): 257–63.
  • 36. US Food and Drug Administration. Ulipristal acetate: new drug review application 22-474. Center for Drug Evaluation and Research. 2009.
  • 37. Zhou L, Xiao B. Emergency contraception with Multiload Cu-375 SL IUD: a multicenter clinical trial. Contraception, 2001;64(2):107–112.
  • 38. Lalitkumar PG, Berger C, Gemzell-Danielsson K. Emergency contraception. Best Pract Res Clin Endocrinol Metab, 2013;27(1):91-101.
  • 39. Zhou L, Xiao B. Emergency contraception with multi-load cu-375 SL IUD: a multicenter clinical trial. Contraception, 2001;64(2):107–112.
  • 40. Liu L, Chen A. A comparative study of mifepristone with Cu-IUD for emergency contraception. Changzhi Med Coll. 2002;61:198–9.
  • 41. Askalani AH, Al-Senity AM, Al-Agizy HM, Salam HI, Al-Masry GI, El-Sadek SM. Evaluation of copper T-200 as a post-coital contraceptive. Egyp J Obstet Gynaecol, 1987;13:63–6.
There are 41 citations in total.

Details

Primary Language Turkish
Journal Section Derlemeler
Authors

Mine İslimye Taşkın

Publication Date April 30, 2012
Submission Date June 13, 2014
Published in Issue Year 2015 Volume: 4 Issue: 1

Cite

APA Taşkın, M. İ. (2012). ACİL KONTRASEPSİYON. Balıkesir Sağlık Bilimleri Dergisi, 4(1), 55-59.

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