Makula Deliği Cerrahisinde Makula Fonksiyonunun Mikroperimetri ve Multifokal Elektroretinogram ile Değerlendirilmesi

Year 2022, Volume: 11 Issue: 1, 129 - 135, 28.02.2022

Sami Yılmaz

https://doi.org/10.53424/balikesirsbd.991527

Abstract

Amaç: Çalışmanın amacı, mikroperimetri (MP) ve multifokal elektroretinogram (mfERG) cihazları ile iç limitan membran (İLM) soyulmasının etkilerini araştırmaktır.
Gereç ve Yöntem: İç limitan membranı soyulan 42 hastanın 42 gözü değerlendirildi. Spektral alan optik koherens tomografi kullanılarak dış katmanların bütünlüğü ölçüldü. MfERG parametreleri (N1 ve P1 genliği, implisit zamanı) ve MP parametreleri de hem başlangıç hem de 12. ayda ölçüldü.
Bulgular: Halka 1'deki P1 genliklerinin ortalaması ameliyat öncesi değere göre arttı (p = 0.002). Ancak, ameliyat sonrası ortalama P1 genlikleri halka 2, 3, 4 ve 5'te mfERG'deki başlangıç değerlerine göre azaldığı tespit edildi (halka 2 için p = 0.016 ve diğer halkalar için p < 0.001). MP'de 37 noktanın başlangıç retina duyarlılığına göre, 12. ayda İLM soyma bölgesinde %22.1 azalma ve 12. ayda iki gözde iki noktada mutlak mikroskotom tespit edildi. Metamorfopsi şikayeti 12. ayda ellipsoid zonun bozulması ile ilişkiliydi (OR = 6.75, p = 0.008).
Sonuç: Makula deliği cerrahisinde İLM soyulması planlanıyorsa, postoperatif makula duyarlılığında olası azalma riski göz önünde bulundurulmalıdır.

Keywords

İç sınırlayıcı zar soyulması, makula deliği cerrahisi, mikroperimetri, multifokal elektroretinogram, metamorfopsi, spektral alan optik koherens tomografi

Supporting Institution

Yok

Project Number

Yok

Evaluation of Macular Function with Microperimetry and Multifocal Electroretinogram in Macular Hole Surgery

Abstract

Objective: To investigate the outcomes of internal limiting membrane (ILM) peeling using microperimetry (MP) and multifocal electroretinogram (mfERG) instruments.
Material and Methods: Forty-two eyes of 42 patients with ILM peeling were evaluated. Unity of outer stratums was assessed using spectral-domain optic coherence tomography. MfERG parameters (N1 and P1 amplitude, implicit time) and MP parameters were also measured both at baseline and month-12.
Results: The mean P1 amplitude in ring 1 increased according to the baseline value (p = 0.002). However, the mean P1 amplitudes were lower compared with baseline values in mfERG in rings 2, 3, 4, and 5 (p = 0.016 for ring 2 and p < 0.001 for other rings). According to the preoperative retinal sensitivity of each of 37-point in MP, there was a reduction of 22.1% at month-12 in the ILM peeling area, and absolute microscotomas were detected in two points of two eyes at month-12. Metamorphopsia was associated with disrupted ellipsoid zone at month-12 (OR = 6.75, p = 0.008).
Conclusion: The potential risk of a decrease in postoperative macular sensitivity should be taken into consideration if ILM peeling is planned in macular hole surgery.

Keywords

Internal limiting membrane peeling, macular hole surgery, microperimery, multifocal electroretinogram, metamorphopsia, spectral domain optic coherence tomography

Project Number

Yok

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