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Makula Deliği Cerrahisinde Makula Fonksiyonunun Mikroperimetri ve Multifokal Elektroretinogram ile Değerlendirilmesi

Yıl 2022, Cilt: 11 Sayı: 1, 129 - 135, 28.02.2022
https://doi.org/10.53424/balikesirsbd.991527

Öz

Amaç: Çalışmanın amacı, mikroperimetri (MP) ve multifokal elektroretinogram (mfERG) cihazları ile iç limitan membran (İLM) soyulmasının etkilerini araştırmaktır.
Gereç ve Yöntem: İç limitan membranı soyulan 42 hastanın 42 gözü değerlendirildi. Spektral alan optik koherens tomografi kullanılarak dış katmanların bütünlüğü ölçüldü. MfERG parametreleri (N1 ve P1 genliği, implisit zamanı) ve MP parametreleri de hem başlangıç hem de 12. ayda ölçüldü.
Bulgular: Halka 1'deki P1 genliklerinin ortalaması ameliyat öncesi değere göre arttı (p = 0.002). Ancak, ameliyat sonrası ortalama P1 genlikleri halka 2, 3, 4 ve 5'te mfERG'deki başlangıç değerlerine göre azaldığı tespit edildi (halka 2 için p = 0.016 ve diğer halkalar için p < 0.001). MP'de 37 noktanın başlangıç retina duyarlılığına göre, 12. ayda İLM soyma bölgesinde %22.1 azalma ve 12. ayda iki gözde iki noktada mutlak mikroskotom tespit edildi. Metamorfopsi şikayeti 12. ayda ellipsoid zonun bozulması ile ilişkiliydi (OR = 6.75, p = 0.008).
Sonuç: Makula deliği cerrahisinde İLM soyulması planlanıyorsa, postoperatif makula duyarlılığında olası azalma riski göz önünde bulundurulmalıdır.

Destekleyen Kurum

Yok

Proje Numarası

Yok

Kaynakça

  • Abdel-Kader M & Wael Mohamed El-Dessouky WM. (2010). Multifocal electroretinogram in retinal vein occlusion. Saudi J Ophthalmol, 24(4), 125-132. https://doi.org/10.1016/j.sjopt.2010.04.005
  • Almony A, Nudleman E, Shah GK, Blinder KJ, Eliott DB, Mittra RA & Tewari A. (2012). Techniques, rationale, and outcomes of internal limiting membrane peeling. Retina, 32(5), 877-891. https://doi.org/10.1097/IAE.0b013e318227ab39
  • Avci R, Mavi Yildiz A & Yilmaz S. (2021). Evaluation of inner retinal dimples and internal limiting membrane flap configuration after temporal inverted ILM flap technique. Eur J Ophthalmol, 31(2), 649-655. https://doi.org/10.1177/1120672120940980
  • Eckardt C, Eckardt U, Groos S, Luciano L & Reale E. (1997). Removal of the internal limiting membrane in macular holes: clinical and morphological findings (in German). Ophthalmologe, 94, 545-551. https://doi.org/10.1007/s003470050156
  • Faria MY, Ferreira NP, Cristóvao DM, Mano S, Sousa DC & Monteiro-Grillo M. (2018). Tomographic structural changes of retinal layers after internal limiting membrane peeling for macular hole surgery. Ophthalmic Research, 59(1), 24-29. https://doi.org/10.1159/000480243
  • Graham SL & Klistorner A. (1998). Electrophysiology: a review of signal origins and applications to glaucoma. Aust N Z J of Ophthalmol, 26(1), 71-85. https://doi.org/10.1046/j.1440-1606.1998.00082.x
  • Imai H & Ohta K. (2010). Microperimetric determination of retinal sensitivity in areas of dissociated optic nerve fiber layer following internal limiting membrane peeling. Jpn J Ophthalmol, 54(5), 435-440. https://doi.org/10.1007/s10384-010-0839-4
  • Ito Y, Terasaki H, Takahashi A, Yamakoshi T, Kondo M & Nakamura M. (2005). Dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for idiopathic macular holes. Ophthalmology, 112(8), 1415-1420. https://doi.org/10.1016/j.ophtha.2005.02.023
  • Mitamura Y & Ohtsuka K. (2005). Relationship of dissociated optic nerve fiber layer appearance to internal limiting membrane peeling. Ophthalmology, 112(10), 1766-1770. https://doi.org/10.1016/j.ophtha.2005.04.026
  • Moschos M, Apostolopoulos M, Ladas J, Theodossiadis P, Malias J, Moschou M, Papaspirou A & Theodossiadis G. (2001). Multifocal ERG changes before and after macular hole surgery. Doc Ophthalmol, 102(1), 31-40. https://doi.org/10.1023/a:1017507220510
  • Si YJ, Kishi S & Aoyagi K. (1999). Assessment of macular function by multifocal electroretinogram before and after macular hole surgery. Br J Ophthalmol, 83(4), 420-444. https://doi.org/10.1136/bjo.83.4.420
  • Sugiura Y, Okamoto F, Okamoto Y, Hiraoka T & Oshika T. (2017). Relationship between metamorphopsia and intraretinal cysts within the fluid cuff after surgery for idiopathic macular hole. Retina, 37(1):70-75. https://doi.org/10.1097/IAE.0000000000001136
  • Sutter EE & Tran D. (1992). The field topography of ERG components in man--I. The photopic luminance response. Vision Res, 32, 433-46. https://doi.org/10.1016/0042-6989(92)90235-b
  • Tadayoni R, Paques M, Massin P, Mouki-Benani S, Mikol J & Gaudric A. (2001). Dissociated optic nerve fiber layer appearance of the fundus after idiopathic epiretinal membrane removal. Ophthalmology, 10, 2279- 2283. https://doi.org/10.1016/s0161-6420(01)00856-9
  • Tadayoni R, Svorenova I, Erginay A, Gaudric A & Massin P. (2012). Decreased retinal sensitivity after internal limiting membrane peeling for macular hole surgery. Br J Ophthalmol, 96(12), 1513-1516. https://doi.org/10.1136/bjophthalmol-2012-302035
  • Wada I, Yoshida S, Kobayashi Y, Zhou Y, Ishikawa K, Nakao S, Hisatomi T, Ikeda Y, Ishibashi T & Sonoda KH. (2017). Quantifying metamorphopsia with M-CHARTS in patients with idiopathic macular hole. Clin Ophthalmol, 11, 1719-1726. https://doi.org/10.2147/OPTH.S144981
  • Wiecek E, Lashkari K, Dakin SC & Bex P. (2014). Novel quantitative assessment of metamorphopsia in maculopathy. Invest Ophthalmol Vis Sci, 56(1), 494-504. https://doi.org/10.1167/iovs.14-15394
  • Yao Y, Qu J, Dong C, Li X, Liang J, Yin H, Huang L, Li Y, Liu P, Pan C, Ding X, Song D, Sadda SR & Zhao M. (2019). The impact of extent of internal limiting membrane peeling on anatomical outcomes of macular hole surgery: results of a 54-week randomized clinical trial. Acta Ophthalmol, 97, 303-312. https://doi.org/10.1111/aos.13853
  • Yilmaz S, Yildiz Mavi A & Avci R. (2021). Foveal Displacement following Temporal Inverted Internal Limiting Membrane Technique for Full Thickness Macular Holes: 12 Months Results. Curr Eye Res, 12, 1-8. https://doi.org/10.1080/02713683.2021.1945110.

Evaluation of Macular Function with Microperimetry and Multifocal Electroretinogram in Macular Hole Surgery

Yıl 2022, Cilt: 11 Sayı: 1, 129 - 135, 28.02.2022
https://doi.org/10.53424/balikesirsbd.991527

Öz

Objective: To investigate the outcomes of internal limiting membrane (ILM) peeling using microperimetry (MP) and multifocal electroretinogram (mfERG) instruments.
Material and Methods: Forty-two eyes of 42 patients with ILM peeling were evaluated. Unity of outer stratums was assessed using spectral-domain optic coherence tomography. MfERG parameters (N1 and P1 amplitude, implicit time) and MP parameters were also measured both at baseline and month-12.
Results: The mean P1 amplitude in ring 1 increased according to the baseline value (p = 0.002). However, the mean P1 amplitudes were lower compared with baseline values in mfERG in rings 2, 3, 4, and 5 (p = 0.016 for ring 2 and p < 0.001 for other rings). According to the preoperative retinal sensitivity of each of 37-point in MP, there was a reduction of 22.1% at month-12 in the ILM peeling area, and absolute microscotomas were detected in two points of two eyes at month-12. Metamorphopsia was associated with disrupted ellipsoid zone at month-12 (OR = 6.75, p = 0.008).
Conclusion: The potential risk of a decrease in postoperative macular sensitivity should be taken into consideration if ILM peeling is planned in macular hole surgery.

Proje Numarası

Yok

Kaynakça

  • Abdel-Kader M & Wael Mohamed El-Dessouky WM. (2010). Multifocal electroretinogram in retinal vein occlusion. Saudi J Ophthalmol, 24(4), 125-132. https://doi.org/10.1016/j.sjopt.2010.04.005
  • Almony A, Nudleman E, Shah GK, Blinder KJ, Eliott DB, Mittra RA & Tewari A. (2012). Techniques, rationale, and outcomes of internal limiting membrane peeling. Retina, 32(5), 877-891. https://doi.org/10.1097/IAE.0b013e318227ab39
  • Avci R, Mavi Yildiz A & Yilmaz S. (2021). Evaluation of inner retinal dimples and internal limiting membrane flap configuration after temporal inverted ILM flap technique. Eur J Ophthalmol, 31(2), 649-655. https://doi.org/10.1177/1120672120940980
  • Eckardt C, Eckardt U, Groos S, Luciano L & Reale E. (1997). Removal of the internal limiting membrane in macular holes: clinical and morphological findings (in German). Ophthalmologe, 94, 545-551. https://doi.org/10.1007/s003470050156
  • Faria MY, Ferreira NP, Cristóvao DM, Mano S, Sousa DC & Monteiro-Grillo M. (2018). Tomographic structural changes of retinal layers after internal limiting membrane peeling for macular hole surgery. Ophthalmic Research, 59(1), 24-29. https://doi.org/10.1159/000480243
  • Graham SL & Klistorner A. (1998). Electrophysiology: a review of signal origins and applications to glaucoma. Aust N Z J of Ophthalmol, 26(1), 71-85. https://doi.org/10.1046/j.1440-1606.1998.00082.x
  • Imai H & Ohta K. (2010). Microperimetric determination of retinal sensitivity in areas of dissociated optic nerve fiber layer following internal limiting membrane peeling. Jpn J Ophthalmol, 54(5), 435-440. https://doi.org/10.1007/s10384-010-0839-4
  • Ito Y, Terasaki H, Takahashi A, Yamakoshi T, Kondo M & Nakamura M. (2005). Dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for idiopathic macular holes. Ophthalmology, 112(8), 1415-1420. https://doi.org/10.1016/j.ophtha.2005.02.023
  • Mitamura Y & Ohtsuka K. (2005). Relationship of dissociated optic nerve fiber layer appearance to internal limiting membrane peeling. Ophthalmology, 112(10), 1766-1770. https://doi.org/10.1016/j.ophtha.2005.04.026
  • Moschos M, Apostolopoulos M, Ladas J, Theodossiadis P, Malias J, Moschou M, Papaspirou A & Theodossiadis G. (2001). Multifocal ERG changes before and after macular hole surgery. Doc Ophthalmol, 102(1), 31-40. https://doi.org/10.1023/a:1017507220510
  • Si YJ, Kishi S & Aoyagi K. (1999). Assessment of macular function by multifocal electroretinogram before and after macular hole surgery. Br J Ophthalmol, 83(4), 420-444. https://doi.org/10.1136/bjo.83.4.420
  • Sugiura Y, Okamoto F, Okamoto Y, Hiraoka T & Oshika T. (2017). Relationship between metamorphopsia and intraretinal cysts within the fluid cuff after surgery for idiopathic macular hole. Retina, 37(1):70-75. https://doi.org/10.1097/IAE.0000000000001136
  • Sutter EE & Tran D. (1992). The field topography of ERG components in man--I. The photopic luminance response. Vision Res, 32, 433-46. https://doi.org/10.1016/0042-6989(92)90235-b
  • Tadayoni R, Paques M, Massin P, Mouki-Benani S, Mikol J & Gaudric A. (2001). Dissociated optic nerve fiber layer appearance of the fundus after idiopathic epiretinal membrane removal. Ophthalmology, 10, 2279- 2283. https://doi.org/10.1016/s0161-6420(01)00856-9
  • Tadayoni R, Svorenova I, Erginay A, Gaudric A & Massin P. (2012). Decreased retinal sensitivity after internal limiting membrane peeling for macular hole surgery. Br J Ophthalmol, 96(12), 1513-1516. https://doi.org/10.1136/bjophthalmol-2012-302035
  • Wada I, Yoshida S, Kobayashi Y, Zhou Y, Ishikawa K, Nakao S, Hisatomi T, Ikeda Y, Ishibashi T & Sonoda KH. (2017). Quantifying metamorphopsia with M-CHARTS in patients with idiopathic macular hole. Clin Ophthalmol, 11, 1719-1726. https://doi.org/10.2147/OPTH.S144981
  • Wiecek E, Lashkari K, Dakin SC & Bex P. (2014). Novel quantitative assessment of metamorphopsia in maculopathy. Invest Ophthalmol Vis Sci, 56(1), 494-504. https://doi.org/10.1167/iovs.14-15394
  • Yao Y, Qu J, Dong C, Li X, Liang J, Yin H, Huang L, Li Y, Liu P, Pan C, Ding X, Song D, Sadda SR & Zhao M. (2019). The impact of extent of internal limiting membrane peeling on anatomical outcomes of macular hole surgery: results of a 54-week randomized clinical trial. Acta Ophthalmol, 97, 303-312. https://doi.org/10.1111/aos.13853
  • Yilmaz S, Yildiz Mavi A & Avci R. (2021). Foveal Displacement following Temporal Inverted Internal Limiting Membrane Technique for Full Thickness Macular Holes: 12 Months Results. Curr Eye Res, 12, 1-8. https://doi.org/10.1080/02713683.2021.1945110.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Sami Yılmaz 0000-0003-1612-3358

Proje Numarası Yok
Yayımlanma Tarihi 28 Şubat 2022
Gönderilme Tarihi 6 Eylül 2021
Yayımlandığı Sayı Yıl 2022 Cilt: 11 Sayı: 1

Kaynak Göster

APA Yılmaz, S. (2022). Evaluation of Macular Function with Microperimetry and Multifocal Electroretinogram in Macular Hole Surgery. Balıkesir Sağlık Bilimleri Dergisi, 11(1), 129-135. https://doi.org/10.53424/balikesirsbd.991527

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