Research Article
BibTex RIS Cite

BEYİN CERRAHİSİNDE HASARLI BEYİN BÖLGESİNİN DEĞERLENDİRİLMESİ VE HASARLI ALANLARIN KLİNİK BELİRTİLERLE İLİŞKİSİ

Year 2024, Volume: 8 Issue: 2, 94 - 106, 31.08.2024
https://doi.org/10.33716/bmedj.1492404

Abstract

Amaç: İskemik hasar görmüş beyin bölgesi ile hastalardaki klinik semptomlar arasındaki ilişki daha önceki postmortem çalışmalarda gösterilmiş ancak canlı olarak gösterilmemiştir. Çalışmanın amacı değerlendirmektir. Hastanın manyetik rezonans (MR) ve bilgisayarlı tomografi (BT) görüntülerinden elde edilen iskemik hasarlı beyin alanları ve bunların hastaların klinik semptomlarıyla ilişkilendirilmesi.
Gereç ve Yöntemler: Bu amaçla hastaların görüntüleri değerlendirildi ve sonuçlar hastaların bildirilen klinik bulgularıyla ilişkilendirildi. Hasarlı alanlar ile klinik semptomlar arasında önemli ölçüde korelasyon zaten tespit edilmiştir. Yapılan kranial görüntüleme yöntemleriyle beyindeki hasarlı alanlar tespit edilebilmektedir. Aynı zamanda nörolojik muayene ile iskemik bölgelerin lokalizasyonu da yapılabilmektedir. Bugüne kadar pek çok işlevsel beyin alanı bu yolla incelenmiştir. Ancak bu tespit genellikle postmortem vakalarda yapılıyordu.
Bulgular: Bu çalışmada ilk kez görüntülerin değerlendirilmesi ile klinik belirtiler arasındaki ilişki araştırıldı.
Sonuç: Mevcut çalışma sonuçları beyin cerrahisi ile ilgili hesaplamalı sinirbilime kaynak olabilir. Klinik ve temel bilimlerde yeni araştırmaların önünü açabilir

References

  • Adams, H. P., B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. (1993) Gordon and E. E. Marsh "Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment." Stroke: 24(1): 35-41.
  • Adams, H. P., P. H. Davis, E. C. Leira, K.-C. Chang, B. H. Bendixen, W. R. Clarke, R. F. (1999) Woolson and M. D. Hansen “Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)." Neurology: 53(1): 126.
  • Arıncı, K. and A. Elhan (1997) "Anatomi (Cilt 1), 2." Baskı, Ankara, Güneş Kitabevi: 341.
  • Arifoğlu, Y. (2016) Her Yönüyle Anatomi, 1. Baskı, İstanbul Tıp Kitabevi, İstanbul.
  • Asplund K, Wester PO. (1994) Stroke management around the world- Sweden. Cerebrovasc Dis; 4:432-434.
  • Bamford, J., P. Sandercock, M. Dennis, J. Burn and C. Warlow (1991"Classification and natural history of clinically identifiable subtypes of cerebral infarction." Lancet: 337(8756): 1521-1526.
  • Biousse, V. (2007) "Adams and Victor's Principles of Neurology, 8th Edition." Journal of Neuro-Ophthalmology: 27(3): 246.
  • Blits, K. C. (1999) "Aristotle: form, function, and comparative anatomy." Anat Rec: 257(2): 58-63.
  • Bradley, W. G. (2004) Neurology in clinical practice: principles of diagnosis and management, Taylor & Francis.
  • Clark D, Boutras N, Mendez M. (2010) The Brain and Behavior. Cambridge Uni Press Third ed.
  • Goldstein, L. B., C. D. Bushnell, R. J. Adams, L. J. Appel, L. T. Braun, S. Chaturvedi, M. A. Creager, A. Culebras, R. H. Eckel, R. G. Hart, J. A. Hinchey, V. J. Howard, E. C. Jauch, S. R. Levine, J. F. Meschia, W. S. Moore, J. V. (2011) Nixon and T. A. Pearson "Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association." Stroke: 42(2): 517-584.
  • Goldstein, L. B., M. R. Jones, D. B. Matchar, L. J. Edwards, J. Hoff, V. Chilukuri, S. B. Armstrong and R. D. Horner (2001) "Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria." Stroke: 32(5): 1091-1098.
  • Kleindorfer, D., J. Khoury, K. Alwell, C. J. Moomaw, D. Woo, M. L. Flaherty, O. Adeoye, S. Ferioli, P. Khatri and B. M. Kissela (2015) "The impact of Magnetic Resonance Imaging (MRI) on ischemic stroke detection and incidence: minimal impact within a population-based study." BMC Neurology: 15: 175.
  • Moore, K. L., A. F. Dalley and A. M. (2013) Agur Clinically oriented anatomy, Lippincott Williams & Wilkins.
  • Murray, C. J. and A. D. Lopez (1997) "Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study." Lancet: 349(9063): 1436-1442.
  • Reidenberg, J. S. and J. T. Laitman (2002) "The new face of gross anatomy." Anat Rec: 269(2): 81-88.
  • Trelease, R. B. (2002) "Anatomical informatics: Millennial perspectives on a newer frontier." The Anatomical Record: 269(5): 224-235.
  • Williams, P. L. (1989) Gray's anatomy, Churchill livingstone Edinburg.

Evaluation of Damaged Brain Area and Correlation of them with Clinic Symptoms in Brain Surgery

Year 2024, Volume: 8 Issue: 2, 94 - 106, 31.08.2024
https://doi.org/10.33716/bmedj.1492404

Abstract

Aim: The relationship between ischemic demaged brain area and upon clinical symptoms on patients have been shown in previous postmortem studies but not living. The aim of study is to evaluate. ischemic demaged brain areas obtained from patient’s magnetic resonans (MR) and computational tomography (CT) images and correlate them with clinical symptoms of patients.
Material And Methods: For this purpose, patients’ images were evaluated and results were correlated with reported clinical findings of patients. Correlation has already been detected between damaged areas and clinical symptoms significantly. Damaged areas in the brain can be detected by performed cranial imaging methods. At the same time, localization of ischemic areas can be made by neurological examination. So far, many functional brain areas have been investigated by this way. But, this determination was usually made on postmortem cases.
Results: In present study, correlation between images evaluation and clinical symptoms was made in the first time.
Conclusions: Present study results can be source for the computational neuroscience related with brain surgery. It can open the way of new researches in the clinical and basic sciences

References

  • Adams, H. P., B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. (1993) Gordon and E. E. Marsh "Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment." Stroke: 24(1): 35-41.
  • Adams, H. P., P. H. Davis, E. C. Leira, K.-C. Chang, B. H. Bendixen, W. R. Clarke, R. F. (1999) Woolson and M. D. Hansen “Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)." Neurology: 53(1): 126.
  • Arıncı, K. and A. Elhan (1997) "Anatomi (Cilt 1), 2." Baskı, Ankara, Güneş Kitabevi: 341.
  • Arifoğlu, Y. (2016) Her Yönüyle Anatomi, 1. Baskı, İstanbul Tıp Kitabevi, İstanbul.
  • Asplund K, Wester PO. (1994) Stroke management around the world- Sweden. Cerebrovasc Dis; 4:432-434.
  • Bamford, J., P. Sandercock, M. Dennis, J. Burn and C. Warlow (1991"Classification and natural history of clinically identifiable subtypes of cerebral infarction." Lancet: 337(8756): 1521-1526.
  • Biousse, V. (2007) "Adams and Victor's Principles of Neurology, 8th Edition." Journal of Neuro-Ophthalmology: 27(3): 246.
  • Blits, K. C. (1999) "Aristotle: form, function, and comparative anatomy." Anat Rec: 257(2): 58-63.
  • Bradley, W. G. (2004) Neurology in clinical practice: principles of diagnosis and management, Taylor & Francis.
  • Clark D, Boutras N, Mendez M. (2010) The Brain and Behavior. Cambridge Uni Press Third ed.
  • Goldstein, L. B., C. D. Bushnell, R. J. Adams, L. J. Appel, L. T. Braun, S. Chaturvedi, M. A. Creager, A. Culebras, R. H. Eckel, R. G. Hart, J. A. Hinchey, V. J. Howard, E. C. Jauch, S. R. Levine, J. F. Meschia, W. S. Moore, J. V. (2011) Nixon and T. A. Pearson "Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association." Stroke: 42(2): 517-584.
  • Goldstein, L. B., M. R. Jones, D. B. Matchar, L. J. Edwards, J. Hoff, V. Chilukuri, S. B. Armstrong and R. D. Horner (2001) "Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria." Stroke: 32(5): 1091-1098.
  • Kleindorfer, D., J. Khoury, K. Alwell, C. J. Moomaw, D. Woo, M. L. Flaherty, O. Adeoye, S. Ferioli, P. Khatri and B. M. Kissela (2015) "The impact of Magnetic Resonance Imaging (MRI) on ischemic stroke detection and incidence: minimal impact within a population-based study." BMC Neurology: 15: 175.
  • Moore, K. L., A. F. Dalley and A. M. (2013) Agur Clinically oriented anatomy, Lippincott Williams & Wilkins.
  • Murray, C. J. and A. D. Lopez (1997) "Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study." Lancet: 349(9063): 1436-1442.
  • Reidenberg, J. S. and J. T. Laitman (2002) "The new face of gross anatomy." Anat Rec: 269(2): 81-88.
  • Trelease, R. B. (2002) "Anatomical informatics: Millennial perspectives on a newer frontier." The Anatomical Record: 269(5): 224-235.
  • Williams, P. L. (1989) Gray's anatomy, Churchill livingstone Edinburg.
There are 18 citations in total.

Details

Primary Language English
Subjects Clinical Sciences (Other)
Journal Section RESEARCH ARTICLE
Authors

Veli Çıtışlı 0000-0002-1631-3795

Early Pub Date August 31, 2024
Publication Date August 31, 2024
Submission Date May 31, 2024
Acceptance Date August 26, 2024
Published in Issue Year 2024 Volume: 8 Issue: 2

Cite

APA Çıtışlı, V. (2024). Evaluation of Damaged Brain Area and Correlation of them with Clinic Symptoms in Brain Surgery. Balıkesir Medical Journal, 8(2), 94-106. https://doi.org/10.33716/bmedj.1492404