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ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ

Year 2021, Volume: 3 Issue: 1, 29 - 38, 30.04.2021
https://doi.org/10.46413/boneyusbad.807225

Abstract

Çölyak; genetik yatkınlığı olan bireylerde glutenin tüketilmesiyle tetiklenen, ince bağırsaklarda inflamasyona neden olan sistemik, immün aracılı bir hastalıktır ve tedavisi glutensiz diyettir. Malabsorbsiyonlar ve glutensiz diyetin bazı besin ögelerini (magnezyum, tiamin, riboflavin, niasin vb.) yeterli miktarda içermemesi nedenleriyle çölyak hastalığında besin ögesi eksiklikleri görülebilir. Bu derlemenin amacı, çölyak hastalığında mikro besin ögesi eksiklerini literatür kapsamında incelemektir.
Çölyak tanısı sırasında sık görülen mikro besin ögesi eksikleri demir, kalsiyum, magnezyum, D vitamini, çinko, folat, niasin, B12 vitamini, riboflavin şeklinde sayılmaktadır.
Sonuçta, çölyak hastalığında vitamin-mineral eksikliklerinin tedavisi için glutensiz diyete uyum ile optimal beslenmenin sağlanmasının gerekliliği görülmektedir. Ayrıca, gereken durumlarda hekim kontrolünde besin takviyesi alınmalıdır.

Supporting Institution

Yoktur.

Project Number

Yoktur.

References

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MICRONUTRIENTS DEFICIENCIES AND NUTRITIONAL RECOMMENDATIONS IN CELIAC DISEASE

Year 2021, Volume: 3 Issue: 1, 29 - 38, 30.04.2021
https://doi.org/10.46413/boneyusbad.807225

Abstract

Celiac disease, which is triggered by consuming gluten in individuals with a genetic predisposition, is a systemic, immune-mediated disease, causing inflammation in the small intestine, and its treatment is the gluten-free diet. Nutritional deficiencies can be observed in celiac disease due to malabsorption, and a gluten-free diet may not contain enough nutrients (magnesium, thiamine, riboflavin, niacin, etc.). This review aims to evaluate micronutrient deficiencies in celiac disease in the context of the literature.
Micronutrient deficiencies frequently seen during the diagnosis of celiac are stated as iron, calcium, magnesium, vitamin D, zinc, folate, niacin, vitamin B12, riboflavin deficiencies.
In conclusion, it is necessary to adherence to a gluten-free diet and to ensure optimal nutrition for the treatment of vitamin-mineral deficiencies in celiac disease. In addition, when necessary, nutritional supplements should be taken under the control of a physician.

Project Number

Yoktur.

References

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  • Babio, N., Alcazar, M., Castillejo, G., Recasens, M., Martinez-Cerezo, F., Gutierrez-Pensado, V., ... Salas-Salvado, J. (2017). Patients With Celiac Disease Reported Higher Consumption of Added Sugar and Total Fat Than Healthy Individuals. Journal of Pediatric Gastroenterology and Nutrition, 64 (1), 63-69. doi:10.1097/MPG.0000000000001251
  • Bai, J. C., Ciacci, C. (2017). World Gastroenterology Organisation Global Guidelines: Celiac Disease February 2017. Journal of Clinical Gastroenterology, 51 (9), 755-768. doi:10.1097/MCG.0000000000000919
  • Balamtekin, N., Aksoy, C., Baysoy, G., Uslu, N., Demir, H., Koksal, G., ... Yuce, A. (2015). Is compliance with gluten-free diet sufficient? Diet composition of celiac patients. The Turkish Journal of Pediatrics, 57 (4), 374-379
  • Beker Şanlı, D., Aliyazıcıoğlu, Y., Kalaycı, A. G. (2015). Pediatrik çölyak hastalarında homosistein, vitamin B12 ve folik asit düzeyleri. Güncel Pediatri, 13, 1-6. doi: 10.4274/jcp.92400
  • Caruso, R., Pallone, F., Stasi, E., Romeo, S., Monteleone, G. (2013). Appropriate nutrient supplementation in celiac disease. Annals of Medicine, 45 (8), 522-531. doi:10.3109/07853890.2013.849383
  • Choudhary, G., Gupta, R. K., Beniwal, J. (2017). Bone Mineral Density in Celiac Disease. Indian Journal of Pediatrics, 84 (5), 344-348. doi:10.1007/s12098-016-2273-1
  • Choung, R. S., Unalp-Arida, A., Ruhl, C. E., Brantner, T. L., Everhart, J. E., Murray, J. A. (2016). Less Hidden Celiac Disease But Increased Gluten Avoidance Without a Diagnosis in the United States: Findings From the National Health and Nutrition Examination Surveys From 2009 to 2014. Mayo Clinic Proceedings, S0025-6196(16)30634-6. doi:10.1016/j.mayocp.2016.10.012
  • Comba, A., Demirbaş, F., Eren, E., Çaltepe, G., Kayadi̇bi̇, H., Kalaycı, A. G. (2018). Çölyak hastalarında serum homosistein düzeylerinin değerlendirilmesi. Pamukkale Tıp Dergisi, 11 (3), 215-222. doi:10.31362/patd.402656 Demirçeken, F. G. (2011). Gluten enteropatisi (Çölyak hastalığı): klasik bir öykü ve güncel gelişmeler. Güncel Gastroenteroloji, 15, 58-72.
  • Di Nardo, G., Villa, M. P., Conti, L., Ranucci, G., Pacchiarotti, C., Principessa, L., ... Parisi, P. (2019). Nutritional Deficiencies in Children with Celiac Disease Resulting from a Gluten-Free Diet: A Systematic Review. Nutrients, 11 (7). doi:10.3390/nu11071588
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  • EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies). (2014b). Scientific opinion on dietary reference values for folate. EFSA Journal, 12 (11), 3893, 59 pp. doi:10.2903/j.efsa.2014.3893
  • EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies). (2015). Scientific opinion on dietary reference values for iron. EFSA Journal, 13 (10), 4254, 115 pp. doi:10.2903/j.efsa.2015.4254
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  • Fathi, F., Ektefa, F., Tafazzoli, M., Rostami, K., Rostami Nejad, M., Fathi, M., … Zali, M. R. (2013). The concentration of serum zinc in celiac patients compared to healthy subjects in Tehran. Gastroenterology and Hepatology from Bed to Bench, 6 (2), 92-95.
  • Fernandez, C. B., Varela-Moreiras, G., Ubeda, N., Alonso-Aperte, E. (2019). Nutritional Status in Spanish Children and Adolescents with Celiac Disease on a Gluten Free Diet Compared to Non-Celiac Disease Controls. Nutrients, 11 (10). 2329. doi: 10.3390/nu11102329.
  • Foschia, M., Horstmann, S., Arendt, E. K., Zannini, E. (2016). Nutritional therapy - Facing the gap between coeliac disease and gluten-free food. International Journal of Food Microbiology, 239, 113-124. doi:10.1016/j.ijfoodmicro.2016.06.014
  • Freeman, H. J. (2015). Iron deficiency anemia in celiac disease. World Journal of Gastroenterology, 21 (31), 9233-9238. doi:10.3748/wjg.v21.i31.9233
  • Garcia-Manzanares, A., Lucendo, A. J. (2011). Nutritional and dietary aspects of celiac disease. Nutrition in Clinical Practice, 26 (2), 163-173. doi:10.1177/0884533611399773
  • Green, P. H., Lebwohl, B., Greywoode, R. (2015). Celiac disease. The Journal of Allergy and Clinical Immunology, 135 (5), 1099-1106. doi:10.1016/j.jaci.2015.01.044
  • Hancock, R., Koren, G. (2004). Celiac disease during pregnancy. Canadian Family Physician Médecin De Famille Canadien, 50, 1361-1363.
  • Kavak, U. S., Yuce, A., Kocak, N., Demir, H., Saltik, I. N., Gurakan, F., Ozen, H. (2003). Bone mineral density in children with untreated and treated celiac disease. Journal of Pediatric Gastroenterology and Nutrition, 37 (4), 434-436. doi:10.1097/00005176-200310000-00007
  • Kreutz, J. M., Adriaanse, M. P. M., van der Ploeg, E. M. C., Vreugdenhil, A. C. E. (2020). Narrative Review: Nutrient Deficiencies in Adults and Children with Treated and Untreated Celiac Disease. Nutrients, 12 (2). doi:10.3390/nu12020500
  • Leivers, C., Martin, G., Gasparetto, M., Shelley, H., Valente, M. (2014). Coeliac disease. Paediatrics and Child Health, 24 (11), 481-484. doi:10.1016/j.paed.2014.05.004
  • Mager, D. R., Qiao, J., Turner, J. (2012). Vitamin D and K status influences bone mineral density and bone accrual in children and adolescents with celiac disease. European Journal of Clinical Nutrition, 66 (4), 488-495. doi:10.1038/ejcn.2011.176
  • Marti-Carvajal, A. J., Sola, I., Lathyris, D., Dayer, M. (2017). Homocysteine-lowering interventions for preventing cardiovascular events. The Cochrane Database of Systematic Reviews, 8 (8), CD006612. doi:10.1002/14651858.CD006612.pub5
  • Martin, J., Geisel, T., Maresch, C., Krieger, K., Stein, J. (2013). Inadequate nutrient intake in patients with celiac disease: results from a German dietary survey. Digestion, 87 (4), 240-246. doi:10.1159/000348850
  • Martin-Masot, R., Nestares, M. T., Diaz-Castro, J., Lopez-Aliaga, I., Alferez, M. J. M., Moreno-Fernandez, J., Maldonado, J. (2019). Multifactorial Etiology of Anemia in Celiac Disease and Effect of Gluten-Free Diet: A Comprehensive Review. Nutrients, 11 (11), 2557. doi:10.3390/nu11112557
  • Nestares, T., Martin-Masot, R., Labella, A., Aparicio, V. A., Flor-Alemany, M., Lopez-Frias, M., Maldonado, J. (2020). Is a Gluten-Free Diet Enough to Maintain Correct Micronutrients Status in Young Patients with Celiac Disease? Nutrients, 12 (3), 844. doi:10.3390/nu12030844
  • Niewinski, M. M. (2008). Advances in celiac disease and gluten-free diet. Journal of The American Dietetic Association, 108 (4), 661-672. doi:10.1016/j.jada.2008.01.011
  • Niro, S., D'Agostino, A., Fratianni, A., Cinquanta, L., Panfili, G. (2019). Gluten-Free Alternative Grains: Nutritional Evaluation and Bioactive Compounds. Foods, 8 (6), 208. doi:10.3390/foods8060208
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There are 55 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section REVIEW ARTICLE
Authors

Esra Tunçer 0000-0001-7151-842X

Nurcan Yabancı Ayhan 0000-0003-1233-246X

Project Number Yoktur.
Publication Date April 30, 2021
Submission Date October 7, 2020
Acceptance Date April 27, 2021
Published in Issue Year 2021 Volume: 3 Issue: 1

Cite

APA Tunçer, E., & Yabancı Ayhan, N. (2021). ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi, 3(1), 29-38. https://doi.org/10.46413/boneyusbad.807225
AMA Tunçer E, Yabancı Ayhan N. ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. April 2021;3(1):29-38. doi:10.46413/boneyusbad.807225
Chicago Tunçer, Esra, and Nurcan Yabancı Ayhan. “ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi 3, no. 1 (April 2021): 29-38. https://doi.org/10.46413/boneyusbad.807225.
EndNote Tunçer E, Yabancı Ayhan N (April 1, 2021) ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi 3 1 29–38.
IEEE E. Tunçer and N. Yabancı Ayhan, “ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ”, Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi, vol. 3, no. 1, pp. 29–38, 2021, doi: 10.46413/boneyusbad.807225.
ISNAD Tunçer, Esra - Yabancı Ayhan, Nurcan. “ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi 3/1 (April 2021), 29-38. https://doi.org/10.46413/boneyusbad.807225.
JAMA Tunçer E, Yabancı Ayhan N. ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. 2021;3:29–38.
MLA Tunçer, Esra and Nurcan Yabancı Ayhan. “ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi, vol. 3, no. 1, 2021, pp. 29-38, doi:10.46413/boneyusbad.807225.
Vancouver Tunçer E, Yabancı Ayhan N. ÇÖLYAK HASTALIĞINDA MİKRO BESİN ÖGESİ EKSİKLİKLERİ VE BESLENME ÖNERİLERİ. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. 2021;3(1):29-38.

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