Research on Aptamer Integrated Surface-Enhanced Raman Spectroscopy Platforms for Diagnosis: Bibliometric Analysis of Topics and Trends

Abstract

Aptamer integrated SERS platforms have become a remarkable and effective method in the diagnosis of various diseases, including cancer. In addition to the advantages of SERS, such as its unique molecular fingerprint identification and ease of use, aptamers offer multiple detection capabilities and more accurate measurements in complex environments. In this study, a bibliometric analysis was conducted on research related to aptamer-integrated SERS platforms for disease diagnosis in order to evaluate developments in the field. Considering all exclusion criteria, a total of 33 publications were obtained with 198 authors contributing and articles published in 24 journals. The average number of citations per document was 16.67, while the international collaboration rate was calculated as 15.15%. China, as the most productive and most cited country, seems to have a significant impact in this field. Furthermore, Cao Xiaowei, one of the most published authors, is Chinese and has the highest h-index among the authors. The most cited article was also produced in collaboration with China. In conclusion, it can be said that China haa a significant influence in this field. Keyword analysis also shows increasing interest in studies on the use of aptamer-based SERS systems in the diagnosis of Alzheimer's disease. A bibliometric analysis of publications on aptamer integrated SERS diagnostic platforms is not currently available in the literature. This study will significantly contribute to the authors gaining different perspectives and establishing new collaboration networks, thus enabling them to develop more effective strategies for use in diagnostic applications.

Keywords

• Aptamer
• Bibliometric Analysis
• Diagnosis
• Raman Spectroscopy
• Surface Enhanced Raman Spectroscopy (SERS)

Ethical Statement

Ethics committee approval was not required for this study because of there was no study on animals or humans.

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