Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi

Tuncay Karakurt; Ayşen Alaman Ağar; Seher Meral; Abdurrahman Onaran

doi:10.35193/bseufbd.603561

Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi

Abstract

Bu çalışmada, 6,6'-((1E,1'E)-(propan-1,3-diilbis(azanyiliden))bis(fenilmetaniliden))bis(3 (oktiloksi)fenol) (HL1) ve 6,6’-((1E,1’E)-(etan-1,2 diilbis(azanyiliden))bis(fenilmetanyiliden))bis(3-oktiloksi)fenol) (HL2) ligandları ile Ni metal atomunun iki farklı kompleksi hazırlanarak FT-IR ve Uv-Vis spektroskopik yöntemleri ile karakterize edilmiştir. İki komplex yapının (HL1Ni ve HL2Ni ) deneysel olarak antifungal aktivite çalışmaları yapılmıştır. Bu çalışmada, Rhizoctonia solani ve Fusarim oxysporum f.sp radicis-lycopersici (FORL) bitki patojenlerine karşı, HL1Ni ve HL2Ni komplekslerinin in vitro koşullar altında etkinlik çalışmaları yürütülmüştür. Etkinliği belirlenen bileşiklerin doz miktarına göre test edilen patojenlere karşı orta ve yüksek düzeyde aktivite sergilediği belirlenmiştir. Ayrıca Komplex yapıların moleküller arası etkileşimlerin daha iyi anlaşılabilmesi amacıyla da bileşiklerin, HOMO-LUMO orbitalleri teoriksel olarak elde edilmiştir. Son olarak da moleküler doking çalışması ile reseptör-ligant etkileşimleri simüle edilmiştir. Bu hesaplama sonucunda bileşiklere ait affinite değerleri (Doking skoru) sırasıyla -6.9 ve -6.4 kcal/mol olarak hesaplanmıştır. Doking skoru ile kompleks yapıların HOMO orbital enerjilerinin birbirleri ile ilişkili olduğu gözlenmiştir.

Keywords

DFT,HOMO-LUMO,Moleküler Doking

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Details

Primary Language

Turkish

Subjects

-

Journal Section

Research Article

Authors

Tuncay Karakurt ^*
0000-0001-6944-9883
Türkiye

Ayşen Alaman Ağar
0000-0002-1316-4835

Seher Meral This is me
0000-0002-6309-8936

Abdurrahman Onaran This is me
0000-0003-0665-8535

Publication Date

March 23, 2020

Submission Date

August 8, 2019

Acceptance Date

January 7, 2020

Published in Issue

Year 2020 Volume: 7 Number: 100. Yıl Özel Sayı

DOI

https://doi.org/10.35193/bseufbd.603561

IZ

https://izlik.org/JA44FE82CT

Cite

RIS / Bibtex

APA

Karakurt, T., Ağar, A. A., Meral, S., & Onaran, A. (2020). Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, 7(100. Yıl Özel Sayı), 198-216. https://doi.org/10.35193/bseufbd.603561

AMA

1.Karakurt T, Ağar AA, Meral S, Onaran A. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 2020;7(100. Yıl Özel Sayı):198-216. doi:10.35193/bseufbd.603561

Chicago

Karakurt, Tuncay, Ayşen Alaman Ağar, Seher Meral, and Abdurrahman Onaran. 2020. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik Ve Antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7 (100. Yıl Özel Sayı): 198-216. https://doi.org/10.35193/bseufbd.603561.

EndNote

Karakurt T, Ağar AA, Meral S, Onaran A (March 1, 2020) Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7 100. Yıl Özel Sayı 198–216.

IEEE

[1]T. Karakurt, A. A. Ağar, S. Meral, and A. Onaran, “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi”, Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, vol. 7, no. 100. Yıl Özel Sayı, pp. 198–216, Mar. 2020, doi: 10.35193/bseufbd.603561.

ISNAD

Karakurt, Tuncay - Ağar, Ayşen Alaman - Meral, Seher - Onaran, Abdurrahman. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik Ve Antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7/100. Yıl Özel Sayı (March 1, 2020): 198-216. https://doi.org/10.35193/bseufbd.603561.

JAMA

1.Karakurt T, Ağar AA, Meral S, Onaran A. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 2020;7:198–216.

MLA

Karakurt, Tuncay, et al. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik Ve Antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, vol. 7, no. 100. Yıl Özel Sayı, Mar. 2020, pp. 198-16, doi:10.35193/bseufbd.603561.

Vancouver

1.Tuncay Karakurt, Ayşen Alaman Ağar, Seher Meral, Abdurrahman Onaran. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 2020 Mar. 1;7(100. Yıl Özel Sayı):198-216. doi:10.35193/bseufbd.603561