Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi

Tuncay Karakurt; Ayşen Alaman Ağar; Seher Meral; Abdurrahman Onaran

doi:10.35193/bseufbd.603561

Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi

Öz

Bu çalışmada, 6,6'-((1E,1'E)-(propan-1,3-diilbis(azanyiliden))bis(fenilmetaniliden))bis(3 (oktiloksi)fenol) (HL1) ve 6,6’-((1E,1’E)-(etan-1,2 diilbis(azanyiliden))bis(fenilmetanyiliden))bis(3-oktiloksi)fenol) (HL2) ligandları ile Ni metal atomunun iki farklı kompleksi hazırlanarak FT-IR ve Uv-Vis spektroskopik yöntemleri ile karakterize edilmiştir. İki komplex yapının (HL1Ni ve HL2Ni ) deneysel olarak antifungal aktivite çalışmaları yapılmıştır. Bu çalışmada, Rhizoctonia solani ve Fusarim oxysporum f.sp radicis-lycopersici (FORL) bitki patojenlerine karşı, HL1Ni ve HL2Ni komplekslerinin in vitro koşullar altında etkinlik çalışmaları yürütülmüştür. Etkinliği belirlenen bileşiklerin doz miktarına göre test edilen patojenlere karşı orta ve yüksek düzeyde aktivite sergilediği belirlenmiştir. Ayrıca Komplex yapıların moleküller arası etkileşimlerin daha iyi anlaşılabilmesi amacıyla da bileşiklerin, HOMO-LUMO orbitalleri teoriksel olarak elde edilmiştir. Son olarak da moleküler doking çalışması ile reseptör-ligant etkileşimleri simüle edilmiştir. Bu hesaplama sonucunda bileşiklere ait affinite değerleri (Doking skoru) sırasıyla -6.9 ve -6.4 kcal/mol olarak hesaplanmıştır. Doking skoru ile kompleks yapıların HOMO orbital enerjilerinin birbirleri ile ilişkili olduğu gözlenmiştir.

Anahtar Kelimeler

DFT,HOMO-LUMO,Moleküler Doking

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

Araştırma Makalesi

Yazarlar

Tuncay Karakurt ^*
0000-0001-6944-9883
Türkiye

Ayşen Alaman Ağar
0000-0002-1316-4835

Seher Meral Bu kişi benim
0000-0002-6309-8936

Abdurrahman Onaran Bu kişi benim
0000-0003-0665-8535

Yayımlanma Tarihi

23 Mart 2020

Gönderilme Tarihi

8 Ağustos 2019

Kabul Tarihi

7 Ocak 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 7 Sayı: 100. Yıl Özel Sayı

DOI

https://doi.org/10.35193/bseufbd.603561

IZ

https://izlik.org/JA44FE82CT

Kaynak Göster

RIS / Bibtex

APA

Karakurt, T., Ağar, A. A., Meral, S., & Onaran, A. (2020). Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, 7(100. Yıl Özel Sayı), 198-216. https://doi.org/10.35193/bseufbd.603561

AMA

1.Karakurt T, Ağar AA, Meral S, Onaran A. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 2020;7(100. Yıl Özel Sayı):198-216. doi:10.35193/bseufbd.603561

Chicago

Karakurt, Tuncay, Ayşen Alaman Ağar, Seher Meral, ve Abdurrahman Onaran. 2020. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7 (100. Yıl Özel Sayı): 198-216. https://doi.org/10.35193/bseufbd.603561.

EndNote

Karakurt T, Ağar AA, Meral S, Onaran A (01 Mart 2020) Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7 100. Yıl Özel Sayı 198–216.

IEEE

[1]T. Karakurt, A. A. Ağar, S. Meral, ve A. Onaran, “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi”, Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, c. 7, sy 100. Yıl Özel Sayı, ss. 198–216, Mar. 2020, doi: 10.35193/bseufbd.603561.

ISNAD

Karakurt, Tuncay - Ağar, Ayşen Alaman - Meral, Seher - Onaran, Abdurrahman. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi 7/100. Yıl Özel Sayı (01 Mart 2020): 198-216. https://doi.org/10.35193/bseufbd.603561.

JAMA

1.Karakurt T, Ağar AA, Meral S, Onaran A. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 2020;7:198–216.

MLA

Karakurt, Tuncay, vd. “Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi”. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, c. 7, sy 100. Yıl Özel Sayı, Mart 2020, ss. 198-16, doi:10.35193/bseufbd.603561.

Vancouver

1.Tuncay Karakurt, Ayşen Alaman Ağar, Seher Meral, Abdurrahman Onaran. Sentezlenen Yeni Ni (II) Komplekslerinin Spektroskopik ve antifungal özelliklerinin İncelenmesi. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi. 01 Mart 2020;7(100. Yıl Özel Sayı):198-216. doi:10.35193/bseufbd.603561