Malezya’da Bitkilerin Erkek Doğurganlık Arttırıcı Özelliklerine Yönelik Hayvan Çalışmaları: Son 16 Yılın Bir Değerlendirmesi

Abstract

İnfertilite, ulusal ve küresel önemi olan ciddi bir halk sağlığı konusudur. İnfertilite prevalansının artıyor olması endişe verici bir senaryodur. Doğal ürünlerden erkeklerde fertiliteyi arttırıcı ajanlar arayışında bitki kökenli ilaçların önemi uzun bir süredir bilinmektedir. Bu çalışma, erkek fertilite verimliliğini arttıran çeşitli bitki araştırmaları yaklaşımlarını özetlemektedir ki bu çalışılmaların bir kısmında bitkiler bizzat kullanılmıştır, bazılarında bitkiden bileşiklerin izole edilmesi için ekstrakt elde edilmiştir, diğer bir kısmı ise farklı hayvan modellerinde denenen aktik bileşiklerdir. Araştırılan literatür, 2000’li yıllardan 2016’ya 16 yıllık çalışmaları kapsamakta olup bunlarda yaklaşık 12 bitkinin erkek fertilite aktivitesine etkilerini gösterilmiştir. Sonuç olarak, bu araştırma, dünyadaki erkeklerde doğurganlık sorununu iyileştirmede gelecekteki bitki uyumu keşfi ne odaklanmada diğer araştırmacılara yardımcı olacaktır.

Keywords

• Herbal bitki,üreme sistemi,doğurganlık,hayvan çalışmaları

Animal Studies on Male Fertility Enhancing Properties of Plants In Malaysia: A Review of The Past 16 Years

Abstract

Infertility is an issue of global and national public health concern. It is a worrying scenario with increasing number of prevalence in infertility. The importance of drugs of plant origin in the quest of fertility enhancing agents for the male from natural products has long been recognized. The present review is an attempt to summarize the fertility enhancing plants with various approaches which are: part of plant have been used, type of extract for isolating the compounds, different isolated compounds (active principles) along with different animal model used. The literature covered is of 16 years from 2000 to 2016 for around 12 plants showing improving fertility activity in males. In conclusion, this review will help other researchers in focusing future herb based drug discovery in improving fertility problem among male across the globe

Keywords

• herbal plant,reproductive system,fertility,animal study

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