Mikroakışkan Kanalda Farklı Vizkozitelerde Sıralı Damlacık Oluşturulması

Year 2021, , 791 - 798, 30.09.2021

Muhammad Saqıb , Emine Yegan Erdem

https://doi.org/10.21605/cukurovaumfd.1005794

Abstract

Mikroakışkan sistemlerde kontrollü ve sıralı damlacık oluşumu çip üzeri damlacık temelli desen oluşturulmasını sağlamak için uygundur. Bu sistemler farklı numuneleri tek bir cihazda ayrı ayrı inceleme fırsatı sunmaktadır. Örneğin iki farklı sıvıdan belli bir sıraya göre damlacıklar oluşturmak mümkündür. Bu çalışmada önce ikili T-birleşimli kanal geometrisi kullanarak farklı vizkozitelerdeki sıvılardan sıralı damlacık oluşumu gösterilmiştir. Damlacıklar su ve gliserol çözeltilerinden oluşturulmuştur. Ayrıca bu makale kapsamında iki farklı sıvının birleştirilmesi ile sonrasında damlacıkların sıra ile oluşturulmasını sağlamak için de tasarlanmış bir sistem çalışılmıştır. Bu çalışmaların biyoanaliz, tarama, hücre bazlı gözlem, kanal içi kimyasal sentez gibi pek çok uygulama alanı olacaktır.

Keywords

Mikroakışkanlar, Damlacık temelli akış, Damlacık dinamiği, Sıralı damlacıklar

Generation of Alternating Droplets with Different Viscosities in a Microfluidic Channel

Abstract

Controlled alternating droplet formation in a microfluidic system can lead to an on-chip droplet-based pattern generation. This enables tracking of different samples individually within the same device. For instance, two different liquids can be segmented in a sequenced, repetitive fashion. In this work, we first show pattern generation by using liquids with unequal viscosities. Droplets of water and glycerol solution are generated in an alternating, repetitive fashion by using a microfluidic system with tapered, double T-junction. We also introduce a microsystem that has a mixing unit that generates a controlled sequence of droplets formed by mixing two different liquids on-chip. We believe that this study can have
applications such as biological analysis, sorting, cell-based monitoring or on-chip chemical synthesis.

Keywords

Microfluidics, Droplet-based flow, Droplet dynamics, Alternating droplets

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