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Hipertansif hastalarda sol ventrikül hipertrofisi ile R ve P dalgalarının zirve zamanları arasındaki ilişki

Year 2024, Volume: 49 Issue: 3, 665 - 672, 30.09.2024
https://doi.org/10.17826/cumj.1472267

Abstract

Amaç: Bu çalışmada hipertansif hastalarda ekokardiyografik olarak değerlendirilen sol ventrikül kitle indeksi (SVKİ) ile belirlenen sol ventrikül hipertrofisi (SVH) ile elektrokardiyografik olarak değerlendirilen R dalgası tepe zamanı (RDTZ) ve P dalgası tepe zamanı (PDTZ) arasındaki ilişkinin araştırılması amaçlandı.
Gereç ve Yöntem: Spesifik tıbbi durumları olanlar hariç, 100 hipertansif hastayı kapsayan kesitsel bir çalışma yürütüldü. Klinik ve demografik veriler toplandı, elektrokardiyografik ve ekokardiyografik incelemeler yapıldı. RDTZ ve PDTZ diğer parametrelerle birlikte değerlendirildi.
Bulgular: 100 hastanın 33'ünde SVH mevcuttu. SVH'li hastalar, SVH olmayanlara kıyasla anlamlı derecede daha yüksek RDTZ (45.6 ± 4.9’ e karşı 35.0 ± 5.5) ve PDTZ (55.5 ± 15.8’ e karşı 49.1 ± 12.5) değerleri gösterdi. Ek olarak, SVH hastalarında sol atriyum ön-arka çapında artış ve deselerasyon zamanında uzama görüldü. QRS fragmantasyonu SVH grubunda daha sık görüldü.
Sonuç: Çalışma, hipertansif hastalarda elektrokardiyografik parametreler (RDTZ ve PDTZ) ile SVH arasındaki ilişkiyi vurgulamaktadır. Bu bulgular, elektrokardiyogramın klinik uygulamada hipertansif hastalarda risk sınıflandırmasına ve terapötik karar vermeye yardımcı olacak SVH değerlendirmesi için invaziv olmayan bir araç olarak potansiyel faydasının altını çizmektedir.

Ethical Statement

The Adana City Training and Research Hospital's ethical committee accepted the cross-sectional study (approval number: 23/11/2023-2955). Every action made throughout the study involving human participants complied with the Helsinki Declaration and the ethical guidelines established by national research committees. Informed consent was also supplied by the individuals.

References

  • Ruilope LM, Schmieder RE. Left ventricular hypertrophy and clinical outcomes in hypertensive patients. Am J Hypertens. 2008;21:500-8.
  • Krzesinski JM, Rorive G, Van Cauwenberge H. Hypertension and left ventricular hypertrophy. Acta Cardiol. 1996;51:143-54.
  • Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG et al. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986;105:173-8.
  • Levy D, Salomon M, D'Agostino RB, Belanger AJ, Kannel WB. Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. Circulation. 1994;90:1786-93.
  • Pérez-Riera AR, de Abreu LC, Barbosa-Barros R, Nikus KC, Baranchuk A. R-peak time: an electrocardiographic parameter with multiple clinical applications. Ann Noninvasive Electrocardiol. 2016;21:10-9.
  • Kalçık M, Yetim M, Doğan T, Eser B, Doğan İ, Bekar L et al. The relationship between R wave peak time and left ventricular mass index in patients with end-stage renal disease on hemodialysis. Int Urol Nephrol. 2019;51:2045-53.
  • Ito K, Miyajima K, Urushida T, Unno K, Okazaki A, Takashima Y et al. Usefulness of P-wave peak time as an electrocardiographic parameter in predicting left ventricular diastolic dysfunction in patients with mitral regurgitation. Ann Noninvasive Electrocardiol. 2022;27:e13000.
  • Hnatkova K, Andršová I, Novotný T, Britton A, Shipley M, Vandenberk B et al. QRS micro-fragmentation as a mortality predictor. Eur Heart J. 2022;43:4177-91.
  • Mitchell C, Rahko PS, Blauwet LA, Canaday B, Finstuen JA, Foster MC et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32:1-64.
  • Devereux RB. Detection of left ventricular hypertrophy by M-mode echocardiography. Anatomic validation, standardization, and comparison to other methods. Hypertension. 1987;9:II19-26.
  • Çinier G, Yılmaz AS, Tekkesin Aİ, Çetin M. Predictors for the prolonged R wave peak time among patients with arterial hypertension. Turk Kardiyol Dern Ars. 2021;49:387-94.
  • Yıldız İ, Özmen Yildiz P, Burak C, Rencüzoğulları İ, Karaveli Gursoy G, Kaya B et al. P wave peak time for predicting an increased left atrial volume index in hemodialysis patients. Med Princ Pract. 2020;29:262-9.
  • Aslan B, Işık F, Akyüz A, İnci Ü, Karadeniz M. Prolonged P wave peak time may be a sign of LV diastolic dysfunction in the coronary slow flow phenomenon. Int J Clin Pract. 2022;2022:4626701.
  • Burak C, Çağdaş M, Rencüzoğulları I, Karabağ Y, Artaç I, Yesin M et al. Association of P wave peak time with left ventricular end-diastolic pressure in patients with hypertension. J Clin Hypertens (Greenwich). 2019;21:608-15.
  • Karakayali M, Artac I, Omar T, Rencuzogullari I, Karabag Y, Hamideyin S. Assessment of the efficacy of the electrocardiographic P-wave peak time in predicting atrial high rate episode in patients with cardiac implantable electronic devices. J Electrocardiol. 2023;80:40-4.
  • Zhang B, Zhen Y, Shen D, Zhang G. Significance of fragmented QRS complexes for identifying left ventricular hypertrophy in patients with hypertension. Ann Noninvasive Electrocardiol. 2015;20:175-80.
  • Kadi H, Kevser A, Ozturk A, Koc F, Ceyhan K. Fragmented QRS complexes are associated with increased left ventricular mass in patients with essential hypertension. Ann Noninvasive Electrocardiol. 2013;18:547-54.
  • Domain G, Chouquet C, Réant P, Bongard V, Vedis T, Rollin A et al. Relationships between left ventricular mass and QRS duration in diverse types of left ventricular hypertrophy. Eur Heart J Cardiovasc Imaging. 2022;23:560-8.
  • Oikonomou E, Theofilis P, Mpahara A, Lazaros G, Niarchou P, Vogiatzi G et al. Diagnostic performance of electrocardiographic criteria in echocardiographic diagnosis of different patterns of left ventricular hypertrophy. Ann Noninvasive Electrocardiol. 2020;25:e12728.

Association between left ventricular hypertrophy and the peak times of the R and P waves in hypertensive patients

Year 2024, Volume: 49 Issue: 3, 665 - 672, 30.09.2024
https://doi.org/10.17826/cumj.1472267

Abstract

Purpose: This study aimed to investigate the relationship between left ventricular hypertrophy (LVH), assessed by echocardiographic left ventricular mass index (LVMI), and electrocardiographically evaluated R wave peak time (RWPT) and P wave peak time (PWPT) in hypertensive patients.
Materials and Methods: A cross-sectional study was conducted involving 100 hypertensive patients, excluding those with specific medical conditions. Clinical and demographic data were collected, and electrocardiographic and echocardiographic examinations were performed. RWPT and PWPT were assessed along with other parameters.
Results: LVH was present in 33 out of 100 patients. Patients with LVH exhibited significantly higher RWPT (45.6 ± 4.9 vs. 35.0 ± 5.5) and PWPT (55.5 ± 15.8 vs. 49.1 ± 12.5) compared to those without LVH. Additionally, LVH patients showed increased left atrium anteroposterior diameter, and prolonged deceleration time. QRS fragmentation was more common in the LVH group.
Conclusion: The study highlights the association between electrocardiographic parameters (RWPT and PWPT) and LVH in hypertensive patients. These findings underscore the potential utility of electrocardiogram as a non-invasive tool for LVH assessment in clinical practice in hypertensive patients, aiding in risk stratification and therapeutic decision-making.

References

  • Ruilope LM, Schmieder RE. Left ventricular hypertrophy and clinical outcomes in hypertensive patients. Am J Hypertens. 2008;21:500-8.
  • Krzesinski JM, Rorive G, Van Cauwenberge H. Hypertension and left ventricular hypertrophy. Acta Cardiol. 1996;51:143-54.
  • Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG et al. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986;105:173-8.
  • Levy D, Salomon M, D'Agostino RB, Belanger AJ, Kannel WB. Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. Circulation. 1994;90:1786-93.
  • Pérez-Riera AR, de Abreu LC, Barbosa-Barros R, Nikus KC, Baranchuk A. R-peak time: an electrocardiographic parameter with multiple clinical applications. Ann Noninvasive Electrocardiol. 2016;21:10-9.
  • Kalçık M, Yetim M, Doğan T, Eser B, Doğan İ, Bekar L et al. The relationship between R wave peak time and left ventricular mass index in patients with end-stage renal disease on hemodialysis. Int Urol Nephrol. 2019;51:2045-53.
  • Ito K, Miyajima K, Urushida T, Unno K, Okazaki A, Takashima Y et al. Usefulness of P-wave peak time as an electrocardiographic parameter in predicting left ventricular diastolic dysfunction in patients with mitral regurgitation. Ann Noninvasive Electrocardiol. 2022;27:e13000.
  • Hnatkova K, Andršová I, Novotný T, Britton A, Shipley M, Vandenberk B et al. QRS micro-fragmentation as a mortality predictor. Eur Heart J. 2022;43:4177-91.
  • Mitchell C, Rahko PS, Blauwet LA, Canaday B, Finstuen JA, Foster MC et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32:1-64.
  • Devereux RB. Detection of left ventricular hypertrophy by M-mode echocardiography. Anatomic validation, standardization, and comparison to other methods. Hypertension. 1987;9:II19-26.
  • Çinier G, Yılmaz AS, Tekkesin Aİ, Çetin M. Predictors for the prolonged R wave peak time among patients with arterial hypertension. Turk Kardiyol Dern Ars. 2021;49:387-94.
  • Yıldız İ, Özmen Yildiz P, Burak C, Rencüzoğulları İ, Karaveli Gursoy G, Kaya B et al. P wave peak time for predicting an increased left atrial volume index in hemodialysis patients. Med Princ Pract. 2020;29:262-9.
  • Aslan B, Işık F, Akyüz A, İnci Ü, Karadeniz M. Prolonged P wave peak time may be a sign of LV diastolic dysfunction in the coronary slow flow phenomenon. Int J Clin Pract. 2022;2022:4626701.
  • Burak C, Çağdaş M, Rencüzoğulları I, Karabağ Y, Artaç I, Yesin M et al. Association of P wave peak time with left ventricular end-diastolic pressure in patients with hypertension. J Clin Hypertens (Greenwich). 2019;21:608-15.
  • Karakayali M, Artac I, Omar T, Rencuzogullari I, Karabag Y, Hamideyin S. Assessment of the efficacy of the electrocardiographic P-wave peak time in predicting atrial high rate episode in patients with cardiac implantable electronic devices. J Electrocardiol. 2023;80:40-4.
  • Zhang B, Zhen Y, Shen D, Zhang G. Significance of fragmented QRS complexes for identifying left ventricular hypertrophy in patients with hypertension. Ann Noninvasive Electrocardiol. 2015;20:175-80.
  • Kadi H, Kevser A, Ozturk A, Koc F, Ceyhan K. Fragmented QRS complexes are associated with increased left ventricular mass in patients with essential hypertension. Ann Noninvasive Electrocardiol. 2013;18:547-54.
  • Domain G, Chouquet C, Réant P, Bongard V, Vedis T, Rollin A et al. Relationships between left ventricular mass and QRS duration in diverse types of left ventricular hypertrophy. Eur Heart J Cardiovasc Imaging. 2022;23:560-8.
  • Oikonomou E, Theofilis P, Mpahara A, Lazaros G, Niarchou P, Vogiatzi G et al. Diagnostic performance of electrocardiographic criteria in echocardiographic diagnosis of different patterns of left ventricular hypertrophy. Ann Noninvasive Electrocardiol. 2020;25:e12728.
There are 19 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Research
Authors

Pınar Özmen Yıldız 0000-0001-6239-850X

Publication Date September 30, 2024
Submission Date April 22, 2024
Acceptance Date June 28, 2024
Published in Issue Year 2024 Volume: 49 Issue: 3

Cite

MLA Özmen Yıldız, Pınar. “Association Between Left Ventricular Hypertrophy and the Peak Times of the R and P Waves in Hypertensive Patients”. Cukurova Medical Journal, vol. 49, no. 3, 2024, pp. 665-72, doi:10.17826/cumj.1472267.