Sigara Kullanma Durumunun Çoklu Fizyolojik Ölçümler Ve Makine Öğrenmesi Teknikleri Kullanılarak Tahmini
Year 2021,
Volume: 23 Issue: 67, 55 - 69, 15.01.2021
Aykut Eken
,
Şevket Çalışkan
Soner Çivilibal
Pinar Deniz Tosun
Abstract
Sigara kullanımı toplumlarda gerek sağlık gerek ekonomik açıdan ciddi kayıplara sebep olmaktadır. Kullanım seviyesinin ölçümünde bir altın standart bulunmamasına rağmen, Fagerstörm Nikotin Bağımlılık Testi (Fagerstörm Test for Nicotine Dependency – FTND) ve HONC (Hooked on Nicotine Checklist) gibi geleneksel testler ve çeşitli nörogörüntüleme yaklaşımları kişinin sigara içme durumunun seviyesi hakkında bir bilgi vermektedir. Bu çalışmada, objektif bir veri olan fizyolojik parametrelerin subjektif bir veri olan bağımlılık testlerinin yerine kullanım seviye tespitinde yeni bir yaklaşım olarak kullanılabileceğini göstermek amaçlanmıştır. Bu amaçla çeşitli seviyelerdeki sigara kullanıcılarından fizyolojik sinyaller (elektrokardiyogram (EKG), Solunum ve Fotopletismografi) toplanmıştır. Bu sinyallerden elde edilen çeşitli öz niteliklerden makine öğrenmesi yaklaşımları kullanılarak katılımcılar düşük seviye veya yüksek seviye olarak tahmin edilmeye çalışılmıştır. Çalışma için önceden FTND bağımlılık testine giren değişik kullanım seviyelerinde 95 katılımcı alınıp bu kişilerden sırasıyla 50 saniyelik EKG, solunum ve fotopletismografi sinyalleri alınmıştır. Öznitelik çıkarımından sonra, parametre optimizasyonu ve sınıflandırma içeren 10 kat içiçe çapraz geçerlilik gerçekleştirilmiştir. Yapılan sınıflandırma sonucunda destek vektör makinesi kullanılarak %93, diskriminant analizi kullanılarak ise %91 doğruluk başarımı elde edilmiştir. Bu sonuçlar, yukarıda belirtilen fizyolojik parametrelerin makine öğrenmesi algoritmaları aracılığı ile sigara kullanım durumunun tespitinde kullanılabileceğini göstermektedir.
Supporting Institution
Düzce Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü
Project Number
2018.06.07.810.
Thanks
Bu çalışma Düzce Üniversitesi Bilimsel Araştırma Projeleri Destek Programı kapsamında desteklenmiştir. (Proje Numarası: 2018.06.07.810.). Çalışmamıza desteklerinden dolayı Dr. Öğ. Ü. İkrime ORKAN UÇAR, Araş. Gör. Melahat Sevgül BAKAY ve Araş. Gör. Sümeyye ARIKAN’a teşekkür ederiz.
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Prediction of smoking status by using multi-physiological measures and machine learning techniques
Year 2021,
Volume: 23 Issue: 67, 55 - 69, 15.01.2021
Aykut Eken
,
Şevket Çalışkan
Soner Çivilibal
Pinar Deniz Tosun
Abstract
Smoking causes severe economic and health losses in communities. Despite the lack of a gold standard for the measurement of usage level, conventional tests such as Fagerstörm Test for Nicotine Dependency (FTND), Hooked on Nicotine Checklist (HONC) and various neuroimaging approaches provide information about the level of smoking status. In this study, usage of objective physiological parameters was proposed as a new approach to detect level of status instead of subjective status tests. In order to achieve this physiological signals (i.e.., electrocardiogram (ECG), respiration and photoplestimography) were acquired from participants from different smoking status levels. Participants’ smoking status levels were predicted as high dependent and low dependent from features extracted from these physiological signals using machine learning approaches. For this study, 95 university students with different levels of smoking status were recruited according to FTND test results and ECG, respiration and photopletismography signals were acquired respectively for 50 seconds to provide data for machine learning models. After feature extraction, a 10 fold nested- cross validation that includes hyperparameter optimization and classification was performed. According to the classification results, 93 % accuracy and 91 % accuracy were found by using Support Vector Machine and Discriminant Analysis respectively. These results revealed that physiological parameters might be used to predict smoking status via machine learning algorithms.
Project Number
2018.06.07.810.
References
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- [5] Heatherton, T. F., Kozlowski, L. T., Frecker, R. C. and Fagerstrom, K.-O. 1991. The Fagerström Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire, Cilt. 86 s. 1119-1127. 10.1111/j.1360-0443.1991.tb01879.x
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- [13] Wetherill, R. R., Rao, H., Hager, N., Wang, J., Franklin, T. R. and Fan, Y. 2019. Classifying and characterizing nicotine use disorder with high accuracy using machine learning and resting-state fMRI, Cilt. 24 s. 811-821. 10.1111/adb.12644
- [14] Mamoshina, P., Kochetov, K., Cortese, F., Kovalchuk, A., Aliper, A., Putin, E., Scheibye-Knudsen, M., Cantor, C. R., Skjodt, N. M., Kovalchuk, O. and Zhavoronkov, A. 2019. Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers, Cilt. 9 s. 142. 10.1038/s41598-018-35704-w
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- [16] Savova, G. K., Ogren, P. V., Duffy, P. H., Buntrock, J. D. and Chute, C. G. 2008. Mayo clinic NLP system for patient smoking status identification, Cilt. 15 s. 25-8. 10.1197/jamia.M2437
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- [20] Devi, M. R., Arvind, T. and Kumar, P. S. 2013. ECG Changes in Smokers and Non Smokers-A Comparative Study, Cilt. 7 s. 824-6. 10.7860/JCDR/2013/5180.2950
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- [24] Irizar-Aramburu, M. I., Martinez-Eizaguirre, J. M., Pacheco-Bravo, P., Diaz-Atienza, M., Aguirre-Arratibel, I., Pena-Pena, M. I., Alba-Latorre, M. and Galparsoro-Goikoetxea, M. 2013. Effectiveness of spirometry as a motivational tool for smoking cessation: a clinical trial, the ESPIMOAT study, Cilt. 14 s. 185. 10.1186/1471-2296-14-185
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- [26] Chatterjee, S., Kumar, S., Dey, S. K. and Chatterjee, P. 1989. Chronic effect of smoking on the electrocardiogram, Cilt. 30 s. 827-39.
- [27] Özdal, M., Pancar, Z., Çınar, V., Bilgiç, M., 2017. Effect of Smoking on Oxygen Saturation in Healthy Sedentary Men and Women, Cilt. 4 s. 178-182.
- [28] Tantisuwat, A. and Thaveeratitham, P. 2014. Effects of smoking on chest expansion, lung function, and respiratory muscle strength of youths, Cilt. 26 s. 167-70. 10.1589/jpts.26.167
- [29] Hampel, F. R. 1971. A general qualitative definition of robustness, Cilt. s. 1887-1896.
- [30] Hampel, F. R. 1974. The influence curve and its role in robust estimation, Cilt. 69 s. 383-393.
- [31] Tibshirani, R. 1996. Regression Shrinkage and Selection via the Lasso, Cilt. 58 s. 267-288.
- [32] Zou, H. and Hastie, T. 2005. Regularization and Variable Selection via the Elastic Net, Cilt. 67 s. 301-320.
[33] Vapnik, V. N. 1995. The Nature of Statistical Learning, Cilt. s.
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- [36] Xi, Q., Sahakian, A. V. and Swiryn, S. 2003. The effect of QRS cancellation on atrial fibrillatory wave signal characteristics in the surface electrocardiogram, Cilt. 36 s. 243-9. 10.1016/s0022-0736(03)00046-3
- [37] Vidaurre, D., Bielza, C. and Larrañaga, P. 2013. Classification of neural signals from sparse autoregressive features, Cilt. 111 s. 21-26. https://doi.org/10.1016/j.neucom.2012.12.013
- [38] Anderson, C. W., Stolz, E. A. and Shamsunder, S. 1998. Multivariate autoregressive models for classification of spontaneous electroencephalographic signals during mental tasks, Cilt. 45 s. 277-86. 10.1109/10.661153
- [39] Xin, Y., Kong, L., Liu, Z., Wang, C., Zhu, H., Gao, M., Zhao, C. and Xu, X. 2018. Multimodal Feature-Level Fusion for Biometrics Identification System on IoMT Platform, Cilt. 6 s. 21418-21426. 10.1109/ACCESS.2018.2815540
- [40] Beltz, A. M., Berenbaum, S. A. and Wilson, S. J. 2015. Sex differences in resting state brain function of cigarette smokers and links to nicotine dependence, Cilt. 23 s. 247-254. 10.1037/pha0000033