The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus

Volume: 43 Number: 1 March 1, 2016
  • Erdal Kaydu
  • İbrahim Erbağcı
  • Seydi Okumuş
  • Ümit Aksoy

The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus

Abstract

Objective: To evaluate the results of corneal cross-linking with UV-A/riboflavin in patients with progressive keratoconus.
Methods: Forty-seven eyes of 30 patients with progressive keratoconus (16 female, 14 male) were included in the study. Uncorrected and the best corrected distance visual acuities, biomicroscopic findings, intraocular pressure measurements, fundoscopic findings, pachymetric measurements and corneal topography parameters were recorded for each patient.
Results: The mean age of the patients was 18.3±5.34 (range: 8-31) years and the mean follow-up duration was 7±2.4 (range: 3-12) months. Following the procedure, the mean decrease in K1, K2, Kav, spherical and cylindrical values were 0.77 D, 0.85 D, 0.80 D, 0.50 D and 0.74 D, respectively (p<0.05). There were no cases with decrease in visual acuity and significant complication during or after the treatment.
Conclusion: Cross-linking with riboflavin/UV-A in patients with progressive keratoconus is an effective procedure. In addition, the preservation of visual acuity and not seen a significant complication indicate that a safe metod. However, large prospective randomized controlled studies are needed to evaluate the long-term effects of this treatment.
Key words: corneal cross-linking, keratoconus, corneal topography

Keywords

References

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  2. Rabinowitz YS. Keratoconus. Surv Ophthalmol 1998;42:297-319.
  3. Krachmer JH, Feder RS, Belin MW. Keratoconus and related non-inflammatory corneal thinning disorders. Surv Ophthalmol 1984;28:293-322.
  4. Wollensak G. Crosslinking treatment of progressive keratoconus:
  5. new hope. Curr Opin Ophthalmol 2006;17:356-360.
  6. Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-ainduced
  7. collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620-627.
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Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Erdal Kaydu This is me

İbrahim Erbağcı This is me

Seydi Okumuş This is me

Ümit Aksoy This is me

Publication Date

March 1, 2016

Submission Date

March 29, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 43 Number: 1

APA
Kaydu, E., Erbağcı, İ., Okumuş, S., & Aksoy, Ü. (2016). The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus. Dicle Medical Journal, 43(1), 67-72. https://doi.org/10.5798/diclemedj.0921.2016.01.0640
AMA
1.Kaydu E, Erbağcı İ, Okumuş S, Aksoy Ü. The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus. Dicle Medical Journal. 2016;43(1):67-72. doi:10.5798/diclemedj.0921.2016.01.0640
Chicago
Kaydu, Erdal, İbrahim Erbağcı, Seydi Okumuş, and Ümit Aksoy. 2016. “The Results of Cross-Linking With Riboflavin UV-A in Patients With Progressive Keratoconus”. Dicle Medical Journal 43 (1): 67-72. https://doi.org/10.5798/diclemedj.0921.2016.01.0640.
EndNote
Kaydu E, Erbağcı İ, Okumuş S, Aksoy Ü (March 1, 2016) The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus. Dicle Medical Journal 43 1 67–72.
IEEE
[1]E. Kaydu, İ. Erbağcı, S. Okumuş, and Ü. Aksoy, “The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus”, Dicle Medical Journal, vol. 43, no. 1, pp. 67–72, Mar. 2016, doi: 10.5798/diclemedj.0921.2016.01.0640.
ISNAD
Kaydu, Erdal - Erbağcı, İbrahim - Okumuş, Seydi - Aksoy, Ümit. “The Results of Cross-Linking With Riboflavin UV-A in Patients With Progressive Keratoconus”. Dicle Medical Journal 43/1 (March 1, 2016): 67-72. https://doi.org/10.5798/diclemedj.0921.2016.01.0640.
JAMA
1.Kaydu E, Erbağcı İ, Okumuş S, Aksoy Ü. The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus. Dicle Medical Journal. 2016;43:67–72.
MLA
Kaydu, Erdal, et al. “The Results of Cross-Linking With Riboflavin UV-A in Patients With Progressive Keratoconus”. Dicle Medical Journal, vol. 43, no. 1, Mar. 2016, pp. 67-72, doi:10.5798/diclemedj.0921.2016.01.0640.
Vancouver
1.Erdal Kaydu, İbrahim Erbağcı, Seydi Okumuş, Ümit Aksoy. The Results of Cross-Linking With Riboflavin/UV-A in Patients With Progressive Keratoconus. Dicle Medical Journal. 2016 Mar. 1;43(1):67-72. doi:10.5798/diclemedj.0921.2016.01.0640