Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience

Abdullah Ulku; Orcun Yalav; A. Gokhan Saritas; Ahmet Rencuzogullari; Kubilay Dalci; İsmail Cem Eray; Ozgur Yagmur; Atılgan Tolga Akcam

doi:10.5798/dicletip.424975

Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience

Abstract

Objective: Limited data are available in regards to the surgical management and outcomes of insulinoma. This study aimed to assess the outcomes associated with surgical treatment of insulinoma, as the most common pancreatic endocrine tumor.

Methods: Medical records of patients who diagnosed as insulinoma from 2000 to 2010 at General Surgery Department of Cukurova University Hospital were retrospectively reviewed. Surgical treatment (resection vs. enucleation) was based on preoperative radiological investigations (abdominal spiral contrast tomography, ultrasound, selective angiography for selected cases) and intra-operative ultrasound imaging once indicated.

Results: Surgically treated thirteen patients (F/M:9/4) who diagnosed with insulinoma were assessed with a mean follow-up of 5.3 (0.5-10) years. Enucleation and distal pancreatectomy were performed for 11 and 2 (one of those is spleen-preserving) patients, respectively. No mortality was recorded. All patients became normoglycemic after surgery without re-operation and with acceptable complication rates (n=3 pancreatic fistula, n=1 pancreatitis).

Conclusion: Surgical treatment of insulinoma is associated with favorable outcomes. Intra-operative ultrasound with manual palpation is still the gold standard for localizing insulinoma. Location, size and relationship with main pancreatic duct of the lesions are key components for the selection of optimal surgical procedure.

Keywords

insulinoma; surgical treatment; enucleation; pancreatic endocrine tumor.

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Abdullah Ulku This is me
0000-0001-5180-1543
Türkiye

Orcun Yalav This is me
0000-0001-9239-4163
Türkiye

A. Gokhan Saritas This is me
Türkiye

Ahmet Rencuzogullari ^*
0000-0002-5993-9536
Türkiye

Kubilay Dalci This is me
0000-0002-5993-9536
Türkiye

İsmail Cem Eray This is me
0000-0002-1560-7740
Türkiye

Ozgur Yagmur This is me
Türkiye

Atılgan Tolga Akcam This is me
0000-0001-7525-3107
Türkiye

Publication Date

June 15, 2018

Submission Date

May 18, 2018

Acceptance Date

April 26, 2018

Published in Issue

Year 2018 Volume: 45 Number: 2

DOI

https://doi.org/10.5798/dicletip.424975

IZ

https://izlik.org/JA49EP36CC

Cite

RIS / Bibtex

APA

Ulku, A., Yalav, O., Saritas, A. G., Rencuzogullari, A., Dalci, K., Eray, İ. C., Yagmur, O., & Akcam, A. T. (2018). Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal, 45(2), 139-146. https://doi.org/10.5798/dicletip.424975

AMA

1.Ulku A, Yalav O, Saritas AG, et al. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal. 2018;45(2):139-146. doi:10.5798/dicletip.424975

Chicago

Ulku, Abdullah, Orcun Yalav, A. Gokhan Saritas, et al. 2018. “Long-Term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal 45 (2): 139-46. https://doi.org/10.5798/dicletip.424975.

EndNote

Ulku A, Yalav O, Saritas AG, Rencuzogullari A, Dalci K, Eray İC, Yagmur O, Akcam AT (June 1, 2018) Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal 45 2 139–146.

IEEE

[1]A. Ulku et al., “Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience”, Dicle Medical Journal, vol. 45, no. 2, pp. 139–146, June 2018, doi: 10.5798/dicletip.424975.

ISNAD

Ulku, Abdullah - Yalav, Orcun - Saritas, A. Gokhan - Rencuzogullari, Ahmet - Dalci, Kubilay - Eray, İsmail Cem - Yagmur, Ozgur - Akcam, Atılgan Tolga. “Long-Term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal 45/2 (June 1, 2018): 139-146. https://doi.org/10.5798/dicletip.424975.

JAMA

1.Ulku A, Yalav O, Saritas AG, Rencuzogullari A, Dalci K, Eray İC, Yagmur O, Akcam AT. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal. 2018;45:139–146.

MLA

Ulku, Abdullah, et al. “Long-Term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal, vol. 45, no. 2, June 2018, pp. 139-46, doi:10.5798/dicletip.424975.

Vancouver

1.Abdullah Ulku, Orcun Yalav, A. Gokhan Saritas, Ahmet Rencuzogullari, Kubilay Dalci, İsmail Cem Eray, Ozgur Yagmur, Atılgan Tolga Akcam. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal. 2018 Jun. 1;45(2):139-46. doi:10.5798/dicletip.424975

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