Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience

Abdullah Ulku; Orcun Yalav; A. Gokhan Saritas; Ahmet Rencuzogullari; Kubilay Dalci; İsmail Cem Eray; Ozgur Yagmur; Atılgan Tolga Akcam

doi:10.5798/dicletip.424975

Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience

Öz

Objective: Limited data are available in regards to the surgical management and outcomes of insulinoma. This study aimed to assess the outcomes associated with surgical treatment of insulinoma, as the most common pancreatic endocrine tumor.

Methods: Medical records of patients who diagnosed as insulinoma from 2000 to 2010 at General Surgery Department of Cukurova University Hospital were retrospectively reviewed. Surgical treatment (resection vs. enucleation) was based on preoperative radiological investigations (abdominal spiral contrast tomography, ultrasound, selective angiography for selected cases) and intra-operative ultrasound imaging once indicated.

Results: Surgically treated thirteen patients (F/M:9/4) who diagnosed with insulinoma were assessed with a mean follow-up of 5.3 (0.5-10) years. Enucleation and distal pancreatectomy were performed for 11 and 2 (one of those is spleen-preserving) patients, respectively. No mortality was recorded. All patients became normoglycemic after surgery without re-operation and with acceptable complication rates (n=3 pancreatic fistula, n=1 pancreatitis).

Conclusion: Surgical treatment of insulinoma is associated with favorable outcomes. Intra-operative ultrasound with manual palpation is still the gold standard for localizing insulinoma. Location, size and relationship with main pancreatic duct of the lesions are key components for the selection of optimal surgical procedure.

Anahtar Kelimeler

insulinoma; surgical treatment; enucleation; pancreatic endocrine tumor.

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Abdullah Ulku Bu kişi benim
0000-0001-5180-1543
Türkiye

Orcun Yalav Bu kişi benim
0000-0001-9239-4163
Türkiye

A. Gokhan Saritas Bu kişi benim
Türkiye

Ahmet Rencuzogullari ^*
0000-0002-5993-9536
Türkiye

Kubilay Dalci Bu kişi benim
0000-0002-5993-9536
Türkiye

İsmail Cem Eray Bu kişi benim
0000-0002-1560-7740
Türkiye

Ozgur Yagmur Bu kişi benim
Türkiye

Atılgan Tolga Akcam Bu kişi benim
0000-0001-7525-3107
Türkiye

Yayımlanma Tarihi

15 Haziran 2018

Gönderilme Tarihi

18 Mayıs 2018

Kabul Tarihi

26 Nisan 2018

Yayımlandığı Sayı

Yıl 2018 Cilt: 45 Sayı: 2

DOI

https://doi.org/10.5798/dicletip.424975

IZ

https://izlik.org/JA49EP36CC

Kaynak Göster

RIS / Bibtex

APA

Ulku, A., Yalav, O., Saritas, A. G., Rencuzogullari, A., Dalci, K., Eray, İ. C., Yagmur, O., & Akcam, A. T. (2018). Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal, 45(2), 139-146. https://doi.org/10.5798/dicletip.424975

AMA

1.Ulku A, Yalav O, Saritas AG, vd. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. diclemedj. 2018;45(2):139-146. doi:10.5798/dicletip.424975

Chicago

Ulku, Abdullah, Orcun Yalav, A. Gokhan Saritas, vd. 2018. “Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal 45 (2): 139-46. https://doi.org/10.5798/dicletip.424975.

EndNote

Ulku A, Yalav O, Saritas AG, Rencuzogullari A, Dalci K, Eray İC, Yagmur O, Akcam AT (01 Haziran 2018) Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. Dicle Medical Journal 45 2 139–146.

IEEE

[1]A. Ulku vd., “Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience”, diclemedj, c. 45, sy 2, ss. 139–146, Haz. 2018, doi: 10.5798/dicletip.424975.

ISNAD

Ulku, Abdullah - Yalav, Orcun - Saritas, A. Gokhan - Rencuzogullari, Ahmet - Dalci, Kubilay - Eray, İsmail Cem - Yagmur, Ozgur - Akcam, Atılgan Tolga. “Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal 45/2 (01 Haziran 2018): 139-146. https://doi.org/10.5798/dicletip.424975.

JAMA

1.Ulku A, Yalav O, Saritas AG, Rencuzogullari A, Dalci K, Eray İC, Yagmur O, Akcam AT. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. diclemedj. 2018;45:139–146.

MLA

Ulku, Abdullah, vd. “Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience”. Dicle Medical Journal, c. 45, sy 2, Haziran 2018, ss. 139-46, doi:10.5798/dicletip.424975.

Vancouver

1.Abdullah Ulku, Orcun Yalav, A. Gokhan Saritas, Ahmet Rencuzogullari, Kubilay Dalci, İsmail Cem Eray, Ozgur Yagmur, Atılgan Tolga Akcam. Long-term Outcomes of Surgical Management of Insulinoma: Single Center Experience. diclemedj. 01 Haziran 2018;45(2):139-46. doi:10.5798/dicletip.424975

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