Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association
Abstract
Granulomatous inflammation is commonly seen in Hodgkin lymphoma. However; the recent literature fails to correlate the subtypes of HL with granuloma. An occasional report describes association of mixed cellularity classical Hodgkin lymphoma with granulomatous reaction. None of other variants of HL are known to manifest with granulomatous reaction. We report a 34-year-old female patient who presented with swelling in right under arm for four months with no history of fever or weight loss. Fine needle aspiration cytology of axillary swelling revealed reactive lymphadenitis. To confirm the diagnosis lymph nodes excision was performed. Histomorphological examination revealed effacement of lymph node architecture by small to intermediate sized lymphoid cells with interspersed mononuclear Reed Sternberg cells like cells along with confluent and discrete non caseating granulomas. Additionally, immunohistochemical staining was performed, which rendered a diagnosis of nodular lymphocyte predominant Hodgkin lymphoma with granulomatous inflammation. This association is uncommon thereby making it pertinent for us to report this rare pathological entity also emphasis on careful microscopic evaluation of lymph node particularly with granulomatous reaction.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Case Report
Publication Date
June 17, 2020
Submission Date
February 14, 2020
Acceptance Date
May 30, 2020
Published in Issue
Year 2020 Volume: 47 Number: 2
APA
Gupta, M., & Nishith, N. (2020). Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal, 47(2), 482-486. https://doi.org/10.5798/dicletip.755782
AMA
1.Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal. 2020;47(2):482-486. doi:10.5798/dicletip.755782
Chicago
Gupta, Monika, and Nilay Nishith. 2020. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal 47 (2): 482-86. https://doi.org/10.5798/dicletip.755782.
EndNote
Gupta M, Nishith N (June 1, 2020) Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal 47 2 482–486.
IEEE
[1]M. Gupta and N. Nishith, “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”, Dicle Medical Journal, vol. 47, no. 2, pp. 482–486, June 2020, doi: 10.5798/dicletip.755782.
ISNAD
Gupta, Monika - Nishith, Nilay. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal 47/2 (June 1, 2020): 482-486. https://doi.org/10.5798/dicletip.755782.
JAMA
1.Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal. 2020;47:482–486.
MLA
Gupta, Monika, and Nilay Nishith. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal, vol. 47, no. 2, June 2020, pp. 482-6, doi:10.5798/dicletip.755782.
Vancouver
1.Monika Gupta, Nilay Nishith. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal. 2020 Jun. 1;47(2):482-6. doi:10.5798/dicletip.755782