Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association
Öz
Granulomatous inflammation is commonly seen in Hodgkin lymphoma. However; the recent literature fails to correlate the subtypes of HL with granuloma. An occasional report describes association of mixed cellularity classical Hodgkin lymphoma with granulomatous reaction. None of other variants of HL are known to manifest with granulomatous reaction. We report a 34-year-old female patient who presented with swelling in right under arm for four months with no history of fever or weight loss. Fine needle aspiration cytology of axillary swelling revealed reactive lymphadenitis. To confirm the diagnosis lymph nodes excision was performed. Histomorphological examination revealed effacement of lymph node architecture by small to intermediate sized lymphoid cells with interspersed mononuclear Reed Sternberg cells like cells along with confluent and discrete non caseating granulomas. Additionally, immunohistochemical staining was performed, which rendered a diagnosis of nodular lymphocyte predominant Hodgkin lymphoma with granulomatous inflammation. This association is uncommon thereby making it pertinent for us to report this rare pathological entity also emphasis on careful microscopic evaluation of lymph node particularly with granulomatous reaction.
Anahtar Kelimeler
Kaynakça
- 1. Pai K, Sharma S, Padmapriya J. Florid granulomatous response masking diagnosis of Hodgkin’s disease in FNA cytology: a diagnostic challenge. Int J Health Sci Res. 2015; 5:468-470.
- 2. Shanbhag S, Ambinder RF. Hodgkin Lymphoma: A Review and update on Recent Progress. CA Cancer J Clin.2018;68:116-32.doi: 10.3322/caac.21438 PMID: 29194581
- 3. Lee AI, Lacasce AS. Nodular lymphocyte predominant Hodgkin Lymphoma.The Oncologist.2009;14:739-51. PMID:19605845 DOI:10.1634/theoncologist 2009-0099.
- 4. Shah KK, Pritt BS, Alexander MP.Histopathological review of granulomatous inflammation. Journal of Clinical Tuberculosis and other Mycobacterial Diseases.2017;7:1-12. http://dx.doi.org/10.1016/j.jctube.2017.02.001
Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
Olgu Sunumu
Yayımlanma Tarihi
17 Haziran 2020
Gönderilme Tarihi
14 Şubat 2020
Kabul Tarihi
30 Mayıs 2020
Yayımlandığı Sayı
Yıl 2020 Cilt: 47 Sayı: 2
APA
Gupta, M., & Nishith, N. (2020). Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal, 47(2), 482-486. https://doi.org/10.5798/dicletip.755782
AMA
1.Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. 2020;47(2):482-486. doi:10.5798/dicletip.755782
Chicago
Gupta, Monika, ve Nilay Nishith. 2020. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal 47 (2): 482-86. https://doi.org/10.5798/dicletip.755782.
EndNote
Gupta M, Nishith N (01 Haziran 2020) Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Medical Journal 47 2 482–486.
IEEE
[1]M. Gupta ve N. Nishith, “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”, diclemedj, c. 47, sy 2, ss. 482–486, Haz. 2020, doi: 10.5798/dicletip.755782.
ISNAD
Gupta, Monika - Nishith, Nilay. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal 47/2 (01 Haziran 2020): 482-486. https://doi.org/10.5798/dicletip.755782.
JAMA
1.Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. 2020;47:482–486.
MLA
Gupta, Monika, ve Nilay Nishith. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Medical Journal, c. 47, sy 2, Haziran 2020, ss. 482-6, doi:10.5798/dicletip.755782.
Vancouver
1.Monika Gupta, Nilay Nishith. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. 01 Haziran 2020;47(2):482-6. doi:10.5798/dicletip.755782