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Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association

Yıl 2020, Cilt: 47 Sayı: 2, 482 - 486, 17.06.2020

Monika Gupta Nilay Nishith

https://doi.org/10.5798/dicletip.755782
Cited By: 1

Öz

Granulomatous inflammation is commonly seen in Hodgkin lymphoma. However; the recent literature fails to correlate the subtypes of HL with granuloma. An occasional report describes association of mixed cellularity classical Hodgkin lymphoma with granulomatous reaction. None of other variants of HL are known to manifest with granulomatous reaction. We report a 34-year-old female patient who presented with swelling in right under arm for four months with no history of fever or weight loss. Fine needle aspiration cytology of axillary swelling revealed reactive lymphadenitis. To confirm the diagnosis lymph nodes excision was performed. Histomorphological examination revealed effacement of lymph node architecture by small to intermediate sized lymphoid cells with interspersed mononuclear Reed Sternberg cells like cells along with confluent and discrete non caseating granulomas. Additionally, immunohistochemical staining was performed, which rendered a diagnosis of nodular lymphocyte predominant Hodgkin lymphoma with granulomatous inflammation. This association is uncommon thereby making it pertinent for us to report this rare pathological entity also emphasis on careful microscopic evaluation of lymph node particularly with granulomatous reaction.

Anahtar Kelimeler

Hodgkin lymphoma Granuloma Sarcoidosis

Kaynakça

  • 1. Pai K, Sharma S, Padmapriya J. Florid granulomatous response masking diagnosis of Hodgkin’s disease in FNA cytology: a diagnostic challenge. Int J Health Sci Res. 2015; 5:468-470.
  • 2. Shanbhag S, Ambinder RF. Hodgkin Lymphoma: A Review and update on Recent Progress. CA Cancer J Clin.2018;68:116-32.doi: 10.3322/caac.21438 PMID: 29194581
  • 3. Lee AI, Lacasce AS. Nodular lymphocyte predominant Hodgkin Lymphoma.The Oncologist.2009;14:739-51. PMID:19605845 DOI:10.1634/theoncologist 2009-0099.
  • 4. Shah KK, Pritt BS, Alexander MP.Histopathological review of granulomatous inflammation. Journal of Clinical Tuberculosis and other Mycobacterial Diseases.2017;7:1-12. http://dx.doi.org/10.1016/j.jctube.2017.02.001
Toplam 4 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumları
Yazarlar

Monika Gupta Bu kişi benim

Nilay Nishith Bu kişi benim

Yayımlanma Tarihi 17 Haziran 2020
Gönderilme Tarihi 14 Şubat 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 47 Sayı: 2

Kaynak Göster

APA Gupta, M., & Nishith, N. (2020). Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Tıp Dergisi, 47(2), 482-486. https://doi.org/10.5798/dicletip.755782
AMA Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. Haziran 2020;47(2):482-486. doi:10.5798/dicletip.755782
Chicago Gupta, Monika, ve Nilay Nishith. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Tıp Dergisi 47, sy. 2 (Haziran 2020): 482-86. https://doi.org/10.5798/dicletip.755782.
EndNote Gupta M, Nishith N (01 Haziran 2020) Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. Dicle Tıp Dergisi 47 2 482–486.
IEEE M. Gupta ve N. Nishith, “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”, diclemedj, c. 47, sy. 2, ss. 482–486, 2020, doi: 10.5798/dicletip.755782.
ISNAD Gupta, Monika - Nishith, Nilay. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Tıp Dergisi 47/2 (Haziran 2020), 482-486. https://doi.org/10.5798/dicletip.755782.
JAMA Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. 2020;47:482–486.
MLA Gupta, Monika ve Nilay Nishith. “Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association”. Dicle Tıp Dergisi, c. 47, sy. 2, 2020, ss. 482-6, doi:10.5798/dicletip.755782.
Vancouver Gupta M, Nishith N. Nodular Lymphocyte Predominant Hodgkin Lymphoma With Sarcoid-Like Granulomas: A Rare Association. diclemedj. 2020;47(2):482-6.

Cited By

Classic Hodgkin lymphoma cloaked in an intense sarcoid-like reaction
Leukemia & Lymphoma
https://doi.org/10.1080/10428194.2022.2081848