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Frequency of Helicobacter pylori in patients underwent endoscopy

Year 2012, Volume: 39 Issue: 2, 197 - 200, 01.06.2012
https://doi.org/10.5798/diclemedj.0921.2012.02.0126

Abstract

Objectives: The aim of this study was to investigate the frequency of Helicobacter pylori in patients underwent endoscopy eastern Anatolia. Materials and methods: The patients whose endoscopic antral biopsies were taken for any reason in our endoscopy unit in February-June 2010 period were included and retrospectively investigated. The frequency of Helicobacter pylori was determined as separating the patients according to general, sex and the age groups. Antral biopsies were stained with hematoxylin-eosin and modified giemsa method and examined under light microscope and reported as (+) mild, (++) moderate, (+++) severe positive according to their intensities. Results: Biopsy specimens of 1298 patients were included into the study. The mean age was 47.5 ± 17.5 years (range 14-88) and 607 of these patients (47%) were male. Histopathological evaluation revealed that, 918 of the patients were (71%) positive and 379 (29%) were negative for Helicobacter pylori. Approximately 60% of our patients had mild, 29% had moderate and 11% had severe positivity for Helicobacter pylori. No significant difference was found in the frequency of Helicobacter pylori between women and men. The frequencies of Helicobacter pylori were 73.2%, 71.5%, 68.6% and 70.4%, respectively, in the age groups of 14-30 years, 31-45 years, 46-60 years and 61-88 years. Conclusion: The frequency of Helicobacter pylori was 71% in Eastern Anatolia Region. No statistically significant difference was found between genders and age groups in term of the frequency of Helicobacter pylori.

References

  • Yücel T, Aygin D, Şen S, Yücel O. The prevalence of Helico- bacter pylori and related factors among university students in Turkey. Jpn J Infect Dis 2008; 61(1): 179-83.
  • Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC. Color Atlas and Textbook of Diagnostic Micro- biology. 6th ed. Philadelphia: Lippincott-Raven Publishers, 2006: 403-408.
  • Özkan TB. Çocuklarda H.pylori enfeksiyonunda seroloji, tanı ve tedavi. Uludağ Üni Tıp Fak Derg 2007; 33(1): 81-5.
  • Muhsen KH, Athamna A, Athamna M, Spungin-Bialik A, Cohen D. Prevalence and risk factors of Helicobacter py- lori infection among healthy 3- to 5-year old Israeli Arab children. Epidemiol Infect 2006; 134(8): 990-6.
  • Tünger Ö. Helicobacter pylori infeksiyonları. İnfeksiyon Dergisi 2008; 22(1): 107-15.
  • Demiray E, Yılmaz Ö, Şarkış C, Soytürk M, Şimşek İ. Com- parison of invasive methods and two different stool antigen tests for diagnosis of H.pylori infection in patients with gas- tric bleeding. World J Gastroenterol 2006; 12(24): 4206-10.
  • Açık Y, Gülbayrak C, Dönder E, Yalnız M. Fırat Tıp merkezi- ne dispeptik yakınmalarla başvuran hastalarda Helicobac- ter pylori sıklığı ve etkileyen faktörler. OMÜ Tıp Fak Derg 2003; 20(1): 82-8.
  • Bulut M, Armağan E, Kıyıcı M, Balcı V, Atar N, Gürel S. Acil servise epigastrik ağrı yakınmasıyla başvuran hastalar- da Helicobacter pylori sıklığı ve tanıda kalitatif serum IgG testinin yeri. Uludağ Üni Tıp Fak Derg 2004; 30(1): 7-10.
  • Da Silva KJM, Villares CA, Monteiro MS, Colauto C, Santos AF, Mattar R. Validation of a rapid stool antigen test for diagnosis of Helicobacter pylori infection. Rev Inst Med Trop Sao Paulo 2010; 52(1): 125-8.
  • Ataseven H, Demir A, Keçeci M. Peptik ülsere bağlı üst gastrointestinal kanamalı olgularda Helicobacter pylori eradikasyonunun fekal antijen testi ile tespiti. FÜ Tıp Fak Derg 2004; 18(2): 199-204.
  • P Chey WD, Murthy U, Toskes P, Carpenter S et al. The 13C-Urea Blood test accurately detecs H.Pylori infection: A United States, multicenter trial Am J Gastroenterol 1999; 94(12): 1522-5.
  • Evans DG, Evans DJ, Lampert HC. Graham DY. Restriction fragment length polymorphism in the adhesin gene hpa A of H.Pylori. Am J Gastroenterol 1995; 90(12): 1282-8.
  • Chey WD, Murthy U, Toskes P, Carpenter S et al. The 13C- Urea Blood test accurately detecs H.Pylori infection: A United States, multicenter trial Am J Gastroenterol 1999; 94(12): 1522-5.
  • Malfertheiner P, Megraud F, Morain C et al. The European Helicobacter Study Group. Current concepts in the man- agement of Helicobacter pylori infection: the Maastricht III Consensus report. Gut 2007; 56(6): 772-81.
  • Prell C, Osterrieder S, Lottspeich C et al. Improved per- formance of a rapid office-based stool test for detection of Helicobacter pylori in children before and after therapy. J Clin Microbiol 2009; 47(16): 3980-4.
  • Murray LJ. McCrum EE, Evans AE et al. Epidemiology of Helicobacter Pylori infection among 4742 randomly se- lected subject from Northern Ireland. Int J Epidemiol 1997; 26(7): 880-7.
  • Açık Y, Gülbayrak C, Dönder E, Yalnız M. Fırat Tıp Merke- zine dispeptik yakınmalarla başvuran hastalarda helicoba- cter pylori sıklığı ve etkileyen faktörler O.M.Ü Tıp Dergisi 2003; 20(1): 82-8.
  • The Eurogast Study Group. Epidemioloji of and risk faktor for Helicobacter pylori infection among 3194 asemptom- atic subject in populations. GUT 1193; 34(12): 1672-6.
  • Veldhuyzen-von-Zonten SJ, Pollak PT, Best LM et al. In- creasing prevalance of Helicobacter Pylori infection with age. J Infect Dis 1994; 169(3): 434-7.
  • Megraud F. Epidemiology of Helicobacter pylori infection: Helicobacter pylori. Gastroenterology Clin Nort America 1993; 22(1): 73-88.
  • Özardalı Hİ, Bitiren M, Nazlıgül Y, Yılmaz N. Şanlıurfa yö- resinde nonerosiv gastritlerde Helicobacter pylori sıklığı. Genel Tıp Derg 1998; 8(1): 149-52.
  • Konakcı N, Gülten M, İbanoğlu MS, et al. Kronik aktif gas- tritli olgularda Helicobacter pylori sıklığı. Uludağ Üniver- sitesi Tıp Fakültesi Dergisi 2010; 36(1): 7-10.
  • Joos A, Nemzeth A, Zsolnay G, Kövari E, Papp J. Gas- tric biopsies and Helicobacter pylori. ORV Hetil 1995; 136(12): 1975-82.

Frequency of Helicobacter pylori in patients underwent endoscopy

Year 2012, Volume: 39 Issue: 2, 197 - 200, 01.06.2012
https://doi.org/10.5798/diclemedj.0921.2012.02.0126

Abstract

Amaç: Bu çalışmanın amacı Doğu Anadolu\'da endoskopi yapılan hastalarda Helicobacter pylori sıklığının araştırılmasıdır. Gereç ve yöntem: Şubat-Haziran 2010 döneminde, endoskopi ünitemizde herhangi bir nedenle endoskopik antrum biyopsisi alınan hastalar çalışmaya alındı ve retrospektif olarak incelendi. Hastaların Helicobacter pylori sıklıkları genel, cinsiyete göre ve yaş gruplarına ayrılarak belirlendi. Antrum biyopsileri hemotoksilen-eozin ve modifiye giemsa yöntemi ile boyanarak ışık mikroskopisinde incelendi ve yoğunluğuna göre, (+) hafif, (++) orta, (+++) ve şiddetli pozitiflik şeklinde raporlandı. Bulgular: Antrum biyopsisi alınan 1298 hasta çalışmaya alındı. Bu hastaların 607\'si (%47) erkek olup, yaş ortalaması 47.5 ± 17.05 yaş (dağılım 14-88) idi. Hastaların 918\'inde (%71) Helicobacter pylori pozitif, 379\'unda (%29) negatif idi. Helicobacter pylori pozitif saptanan hastaların yaklaşık %60\'ında hafif, %29\'unda orta, %11\'inde ağır şiddette pozitiflik rapor edildi. Kadınlarda ve ekeklerde sıklık benzerdi. 14-30 yaş, 31-45 yaş, 46-60 yaş, 61-88 yaş gruplarında Helicobacter pylori sıklığı sırasıyla %73,2, %71.5, %68.6, %70.4 idi. Sonuç: Doğu Anadolu Bölgesinde Helicobacter pylori sıklığı %71\'dir. Helicobacter pylori sıklığı açısından cinsiyet ve yaş grupları arasında anlamlı farklılık bulunmadı.

References

  • Yücel T, Aygin D, Şen S, Yücel O. The prevalence of Helico- bacter pylori and related factors among university students in Turkey. Jpn J Infect Dis 2008; 61(1): 179-83.
  • Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC. Color Atlas and Textbook of Diagnostic Micro- biology. 6th ed. Philadelphia: Lippincott-Raven Publishers, 2006: 403-408.
  • Özkan TB. Çocuklarda H.pylori enfeksiyonunda seroloji, tanı ve tedavi. Uludağ Üni Tıp Fak Derg 2007; 33(1): 81-5.
  • Muhsen KH, Athamna A, Athamna M, Spungin-Bialik A, Cohen D. Prevalence and risk factors of Helicobacter py- lori infection among healthy 3- to 5-year old Israeli Arab children. Epidemiol Infect 2006; 134(8): 990-6.
  • Tünger Ö. Helicobacter pylori infeksiyonları. İnfeksiyon Dergisi 2008; 22(1): 107-15.
  • Demiray E, Yılmaz Ö, Şarkış C, Soytürk M, Şimşek İ. Com- parison of invasive methods and two different stool antigen tests for diagnosis of H.pylori infection in patients with gas- tric bleeding. World J Gastroenterol 2006; 12(24): 4206-10.
  • Açık Y, Gülbayrak C, Dönder E, Yalnız M. Fırat Tıp merkezi- ne dispeptik yakınmalarla başvuran hastalarda Helicobac- ter pylori sıklığı ve etkileyen faktörler. OMÜ Tıp Fak Derg 2003; 20(1): 82-8.
  • Bulut M, Armağan E, Kıyıcı M, Balcı V, Atar N, Gürel S. Acil servise epigastrik ağrı yakınmasıyla başvuran hastalar- da Helicobacter pylori sıklığı ve tanıda kalitatif serum IgG testinin yeri. Uludağ Üni Tıp Fak Derg 2004; 30(1): 7-10.
  • Da Silva KJM, Villares CA, Monteiro MS, Colauto C, Santos AF, Mattar R. Validation of a rapid stool antigen test for diagnosis of Helicobacter pylori infection. Rev Inst Med Trop Sao Paulo 2010; 52(1): 125-8.
  • Ataseven H, Demir A, Keçeci M. Peptik ülsere bağlı üst gastrointestinal kanamalı olgularda Helicobacter pylori eradikasyonunun fekal antijen testi ile tespiti. FÜ Tıp Fak Derg 2004; 18(2): 199-204.
  • P Chey WD, Murthy U, Toskes P, Carpenter S et al. The 13C-Urea Blood test accurately detecs H.Pylori infection: A United States, multicenter trial Am J Gastroenterol 1999; 94(12): 1522-5.
  • Evans DG, Evans DJ, Lampert HC. Graham DY. Restriction fragment length polymorphism in the adhesin gene hpa A of H.Pylori. Am J Gastroenterol 1995; 90(12): 1282-8.
  • Chey WD, Murthy U, Toskes P, Carpenter S et al. The 13C- Urea Blood test accurately detecs H.Pylori infection: A United States, multicenter trial Am J Gastroenterol 1999; 94(12): 1522-5.
  • Malfertheiner P, Megraud F, Morain C et al. The European Helicobacter Study Group. Current concepts in the man- agement of Helicobacter pylori infection: the Maastricht III Consensus report. Gut 2007; 56(6): 772-81.
  • Prell C, Osterrieder S, Lottspeich C et al. Improved per- formance of a rapid office-based stool test for detection of Helicobacter pylori in children before and after therapy. J Clin Microbiol 2009; 47(16): 3980-4.
  • Murray LJ. McCrum EE, Evans AE et al. Epidemiology of Helicobacter Pylori infection among 4742 randomly se- lected subject from Northern Ireland. Int J Epidemiol 1997; 26(7): 880-7.
  • Açık Y, Gülbayrak C, Dönder E, Yalnız M. Fırat Tıp Merke- zine dispeptik yakınmalarla başvuran hastalarda helicoba- cter pylori sıklığı ve etkileyen faktörler O.M.Ü Tıp Dergisi 2003; 20(1): 82-8.
  • The Eurogast Study Group. Epidemioloji of and risk faktor for Helicobacter pylori infection among 3194 asemptom- atic subject in populations. GUT 1193; 34(12): 1672-6.
  • Veldhuyzen-von-Zonten SJ, Pollak PT, Best LM et al. In- creasing prevalance of Helicobacter Pylori infection with age. J Infect Dis 1994; 169(3): 434-7.
  • Megraud F. Epidemiology of Helicobacter pylori infection: Helicobacter pylori. Gastroenterology Clin Nort America 1993; 22(1): 73-88.
  • Özardalı Hİ, Bitiren M, Nazlıgül Y, Yılmaz N. Şanlıurfa yö- resinde nonerosiv gastritlerde Helicobacter pylori sıklığı. Genel Tıp Derg 1998; 8(1): 149-52.
  • Konakcı N, Gülten M, İbanoğlu MS, et al. Kronik aktif gas- tritli olgularda Helicobacter pylori sıklığı. Uludağ Üniver- sitesi Tıp Fakültesi Dergisi 2010; 36(1): 7-10.
  • Joos A, Nemzeth A, Zsolnay G, Kövari E, Papp J. Gas- tric biopsies and Helicobacter pylori. ORV Hetil 1995; 136(12): 1975-82.
There are 23 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ahmet Uyanıkoğlu This is me

Muharrem Coşkun This is me

Doğan Nasır Binici This is me

Şiir Uçar This is me

Yunus İlyas Kibar This is me

Ahmet Tay This is me

Yasin Öztürk This is me

Publication Date June 1, 2012
Submission Date March 2, 2015
Published in Issue Year 2012 Volume: 39 Issue: 2

Cite

APA Uyanıkoğlu, A., Coşkun, M., Binici, D. N., Uçar, Ş., et al. (2012). Frequency of Helicobacter pylori in patients underwent endoscopy. Dicle Tıp Dergisi, 39(2), 197-200. https://doi.org/10.5798/diclemedj.0921.2012.02.0126
AMA Uyanıkoğlu A, Coşkun M, Binici DN, Uçar Ş, Kibar Yİ, Tay A, Öztürk Y. Frequency of Helicobacter pylori in patients underwent endoscopy. diclemedj. June 2012;39(2):197-200. doi:10.5798/diclemedj.0921.2012.02.0126
Chicago Uyanıkoğlu, Ahmet, Muharrem Coşkun, Doğan Nasır Binici, Şiir Uçar, Yunus İlyas Kibar, Ahmet Tay, and Yasin Öztürk. “Frequency of Helicobacter Pylori in Patients Underwent Endoscopy”. Dicle Tıp Dergisi 39, no. 2 (June 2012): 197-200. https://doi.org/10.5798/diclemedj.0921.2012.02.0126.
EndNote Uyanıkoğlu A, Coşkun M, Binici DN, Uçar Ş, Kibar Yİ, Tay A, Öztürk Y (June 1, 2012) Frequency of Helicobacter pylori in patients underwent endoscopy. Dicle Tıp Dergisi 39 2 197–200.
IEEE A. Uyanıkoğlu, “Frequency of Helicobacter pylori in patients underwent endoscopy”, diclemedj, vol. 39, no. 2, pp. 197–200, 2012, doi: 10.5798/diclemedj.0921.2012.02.0126.
ISNAD Uyanıkoğlu, Ahmet et al. “Frequency of Helicobacter Pylori in Patients Underwent Endoscopy”. Dicle Tıp Dergisi 39/2 (June 2012), 197-200. https://doi.org/10.5798/diclemedj.0921.2012.02.0126.
JAMA Uyanıkoğlu A, Coşkun M, Binici DN, Uçar Ş, Kibar Yİ, Tay A, Öztürk Y. Frequency of Helicobacter pylori in patients underwent endoscopy. diclemedj. 2012;39:197–200.
MLA Uyanıkoğlu, Ahmet et al. “Frequency of Helicobacter Pylori in Patients Underwent Endoscopy”. Dicle Tıp Dergisi, vol. 39, no. 2, 2012, pp. 197-00, doi:10.5798/diclemedj.0921.2012.02.0126.
Vancouver Uyanıkoğlu A, Coşkun M, Binici DN, Uçar Ş, Kibar Yİ, Tay A, Öztürk Y. Frequency of Helicobacter pylori in patients underwent endoscopy. diclemedj. 2012;39(2):197-200.

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