Abstract
Melkersson-Rosenthal syndrome is a granulomatous disease which is characterized by the triad of recurrent peripheral facial palsy, orofacial edema, and fissured tongue. In this article we presented one case who, since childhood, had had peripheral paralysis attack twice on the left side and once in the right side and was diagnosed with idiopathic paralysis before being admitted to our clinic for the second time with the preliminary diagnosis of peripheral facial paralysis on the right side and then diagnosed and followed up with the diagnosis of Melkersson-Rosenthal Syndrome (MRS). We presented this case since the facial paralysis recurred on the different side and in different times and also since it remained resistant to treatment of steroids and it is seen rarely in adolescence. However, further clinic-pathological studies are required to investigate the etiology and find right treatment procedures for this syndrome
References
- Zimmer WM, Rogers RS, Reeve CM, et al. Orofacial manifestations
- of Melkersson-Rosenthal syndrome. A study of
- patients and review of 220 cases from the literature. Oral
- Surg Oral Med Oral Pathol 1992;74: 610-619.
- Ziem PE, Pfrommer C, Goerdt S, et al. Melkersson-Rosenthal
- syndrome in childhood: a challenge in differential diagnosis
- and treatment. Br J Dermatol 2000; 143:860-863.
- Armstrong DK, Burrows D. Orofacial granulomatosis. Int J
- Dermatol 1995;34:830-833.
- Worsaae N, Christensen KC, Schiodt M, et al. MRS and cheilitis
- granulomatosa. A clinicopathological study of thirty
- three patients with special reference to their oral lesions.
- Oral Surg Oral Med Oral Pathol 1982;54:404-413.
- Greene RM, Rogers RS. MRS: a review of 36 patients. J Am
- Acad Dermatol 1989;21:1263-1270.
- Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232.
- Wong GA, Shear NH. Melkersson-Rosenthal syndrome associated
- with allergic contact dermatitis from octyl and dodecyl
- gallates. Contact Dermatitis 2003;49:266-267.
- Camacho-Alonso F, Bermejo-Fenoll A, Lopez-Jornet P.
- Miescher’s cheilitis granulomatosa. A presentation of five
- cases. Med Oral Patol Oral Cir Buccal 2004;9:427-429.
- Rogers RS 3rd. Melkersson-Rosenthal syndrome and orofacial
- granulomatosis. Dermatol Clin 1996;14:371-379.
- May M, Klein SR. Differrential diagnosis of facial nerve
- palsy. Otolaryngol Clin North Am 1991;24:613-645.
- Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232.
- Perez-Calderon R, Gonzalo-Garijo MA, Chaves A, et al.
- Cheilitis granulomatosa of Melkersson-Rosenthal syndrome:
- treatment with intralesional corticosteroid injections.
- Allergol Immunopathol 2004;32:36-38.
- Kruse-Losler B, Presser D, Metze D, et al. Surgical treatment
- of persistent macrocheilia in patients with Melkersson-Rosenthal
- syndrome and cheilitis granulomatosa. Arch
- Dermatol 2005;141:1085-1091.
- Özdemir HH, Demir CF, M. Berilgen S, ve ark. Gebelik ve
- fasiyal dipleji: Nadir bir olgu. Dicle Med J 2012;39:419-421.
Abstract
Melkersson-Rosenthal Sendromu yineleyen periferik fasiyal paralizi, orofasiyal ödem ve fissürlü dil triadı ile karakterize granülomatöz hastalıktır. Bu yazımızda çocukluktan itibaren 2 kez sol ve bir kez sağ taraftan periferik paralizi atağı geçiren ve idiopatik fasiyal paralizi tanısı alan olgunın kliniğimize tekrar sağ tarafta periferik fasiyal paralizi ön tanısı ile yatırılıp tetkik ve takip sonucunda Melkersson-Rosenthal Sendromu (MRS) tanısı alan hastada; fasiyal paralizinin farklı tarafta ve farklı zamanlarda tekrarlayıcı olması ve tedaviye dirençli olması ve ayrıca gençlik çağında ender görülüyor olması nedeniyle sunulmuştur. Ancak bu sendromla ilgili gerek doğru etiyoloji ve gerekse sonuç veren tedavi açısından klinikopatolojik ek çalışmalara ihtiyaç duyulmaktadır. Anahtar kelimeler: Melkersson-rosenthal sendromu, fasiyal paralizi, fissürlü dil
References
- Zimmer WM, Rogers RS, Reeve CM, et al. Orofacial manifestations
- of Melkersson-Rosenthal syndrome. A study of
- patients and review of 220 cases from the literature. Oral
- Surg Oral Med Oral Pathol 1992;74: 610-619.
- Ziem PE, Pfrommer C, Goerdt S, et al. Melkersson-Rosenthal
- syndrome in childhood: a challenge in differential diagnosis
- and treatment. Br J Dermatol 2000; 143:860-863.
- Armstrong DK, Burrows D. Orofacial granulomatosis. Int J
- Dermatol 1995;34:830-833.
- Worsaae N, Christensen KC, Schiodt M, et al. MRS and cheilitis
- granulomatosa. A clinicopathological study of thirty
- three patients with special reference to their oral lesions.
- Oral Surg Oral Med Oral Pathol 1982;54:404-413.
- Greene RM, Rogers RS. MRS: a review of 36 patients. J Am
- Acad Dermatol 1989;21:1263-1270.
- Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232.
- Wong GA, Shear NH. Melkersson-Rosenthal syndrome associated
- with allergic contact dermatitis from octyl and dodecyl
- gallates. Contact Dermatitis 2003;49:266-267.
- Camacho-Alonso F, Bermejo-Fenoll A, Lopez-Jornet P.
- Miescher’s cheilitis granulomatosa. A presentation of five
- cases. Med Oral Patol Oral Cir Buccal 2004;9:427-429.
- Rogers RS 3rd. Melkersson-Rosenthal syndrome and orofacial
- granulomatosis. Dermatol Clin 1996;14:371-379.
- May M, Klein SR. Differrential diagnosis of facial nerve
- palsy. Otolaryngol Clin North Am 1991;24:613-645.
- Cockerham KP, Hidayat AA, Cockerham GC, et al. Melkersson-Rosenthal syndrome: new clinicopathologic findings in 4 cases. Arch Ophthalmol 2000;118:227-232.
- Perez-Calderon R, Gonzalo-Garijo MA, Chaves A, et al.
- Cheilitis granulomatosa of Melkersson-Rosenthal syndrome:
- treatment with intralesional corticosteroid injections.
- Allergol Immunopathol 2004;32:36-38.
- Kruse-Losler B, Presser D, Metze D, et al. Surgical treatment
- of persistent macrocheilia in patients with Melkersson-Rosenthal
- syndrome and cheilitis granulomatosa. Arch
- Dermatol 2005;141:1085-1091.
- Özdemir HH, Demir CF, M. Berilgen S, ve ark. Gebelik ve
- fasiyal dipleji: Nadir bir olgu. Dicle Med J 2012;39:419-421.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research Articles |
| Authors | |
| Publication Date | May 9, 2015 |
| Submission Date | May 9, 2015 |
| Published in Issue | Year 2015 Volume: 42 Issue: 1 |