Abstract
References
- 1.Leitner DR, Frühbeck G, Yumuk V, et al. Obesityand type 2 diabetes:Two diseases with a need forcombined treatment strategies-EASO can lead theway. Obes Facts. 2017; 10: 483-92.
- 2.Rueda- Clausen CF, Ogunleye AA, Sharma AM.Health benefits of long-term weight-lossmaintenance. Annu Rev Nutr. 2015; 35: 475-516
- 3.Flegal KM, Carroll MD, Ogden CL, Johnson CL.Prevalence and trends in obesity among US adults,1999-2000. JAMA. 2002; 288: 1723-7.
Abstract
Objective: To examine the association of weight loss achieved through obesity treatment with platelet number and markers (mean platelet volume, MPV; plateletcrit, PCT; platelet/lymphocyte ratio, PLR; and platelet distribution width, PDW) in morbidly obese patients.
Methods: A total of 300 patients diagnosed with morbid obesity between 2017 and 2019 were included in this retrospective study. Weight at baseline and 6 months, body mass index (BMI), complete blood count (platelet, lymphocyte, plateletcrit, platelet/lymphocyte ratio, and platelet distribution width), and demographic data were evaluated.
Results: A total of 300 morbidly obese patients with a BMI ≥ 40 kg/m2 were included. A weight loss of ≥ 10% was considered “significant”, and a weight loss of < 10% was considered insignificant. A significant decrease in platelet number was found in association with weight loss (p < 0.05), as were the changes in PCT and PLR. These findings suggest that platelet markers PCT and PLR may be associated with the degree of weight loss.
Conclusion: Our results suggest that platelet markers simply obtained through a complete blood count may be utilized in the treatment and follow-up of obesity, which may lead to a number of different conditions such as coronary artery disease, cerebrovascular events, and myocardial infarction through predisposition to thrombosis.
References
- 1.Leitner DR, Frühbeck G, Yumuk V, et al. Obesityand type 2 diabetes:Two diseases with a need forcombined treatment strategies-EASO can lead theway. Obes Facts. 2017; 10: 483-92.
- 2.Rueda- Clausen CF, Ogunleye AA, Sharma AM.Health benefits of long-term weight-lossmaintenance. Annu Rev Nutr. 2015; 35: 475-516
- 3.Flegal KM, Carroll MD, Ogden CL, Johnson CL.Prevalence and trends in obesity among US adults,1999-2000. JAMA. 2002; 288: 1723-7.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Original Articles |
| Authors | |
| Publication Date | December 1, 2021 |
| Submission Date | August 9, 2021 |
| Published in Issue | Year 2021 Volume: 48 Issue: 4 |
