Objective: To examine the association of weight loss achieved through obesity treatment with platelet number and markers (mean platelet volume, MPV; plateletcrit, PCT; platelet/lymphocyte ratio, PLR; and platelet distribution width, PDW) in morbidly obese patients.
Methods: A total of 300 patients diagnosed with morbid obesity between 2017 and 2019 were included in this retrospective study. Weight at baseline and 6 months, body mass index (BMI), complete blood count (platelet, lymphocyte, plateletcrit, platelet/lymphocyte ratio, and platelet distribution width), and demographic data were evaluated.
Results: A total of 300 morbidly obese patients with a BMI ≥ 40 kg/m2 were included. A weight loss of ≥ 10% was considered “significant”, and a weight loss of < 10% was considered insignificant. A significant decrease in platelet number was found in association with weight loss (p < 0.05), as were the changes in PCT and PLR. These findings suggest that platelet markers PCT and PLR may be associated with the degree of weight loss.
Conclusion: Our results suggest that platelet markers simply obtained through a complete blood count may be utilized in the treatment and follow-up of obesity, which may lead to a number of different conditions such as coronary artery disease, cerebrovascular events, and myocardial infarction through predisposition to thrombosis.
morbid obesity plateletcrit mean platelet volume body mass index
Birincil Dil | İngilizce |
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Konular | Sağlık Kurumları Yönetimi |
Bölüm | Original Articles |
Yazarlar | |
Yayımlanma Tarihi | 1 Aralık 2021 |
Gönderilme Tarihi | 9 Ağustos 2021 |
Yayımlandığı Sayı | Yıl 2021 Cilt: 48 Sayı: 4 |