The Association Between Weight Loss and Platelet Markers in Morbidly Obese Patients

Yıl 2021, Cilt: 48 Sayı: 4, 754 - 760, 01.12.2021

Gamze Öztürk Müzeyyen Aslaner Ak Sehmus Ertop

https://doi.org/10.5798/dicletip.1037628

Cited By: 1

Öz

The Association Between Weight Loss and Platelet Markers in Morbidly Obese Patients

Öz

Objective: To examine the association of weight loss achieved through obesity treatment with platelet number and markers (mean platelet volume, MPV; plateletcrit, PCT; platelet/lymphocyte ratio, PLR; and platelet distribution width, PDW) in morbidly obese patients.
Methods: A total of 300 patients diagnosed with morbid obesity between 2017 and 2019 were included in this retrospective study. Weight at baseline and 6 months, body mass index (BMI), complete blood count (platelet, lymphocyte, plateletcrit, platelet/lymphocyte ratio, and platelet distribution width), and demographic data were evaluated.
Results: A total of 300 morbidly obese patients with a BMI ≥ 40 kg/m2 were included. A weight loss of ≥ 10% was considered “significant”, and a weight loss of < 10% was considered insignificant. A significant decrease in platelet number was found in association with weight loss (p < 0.05), as were the changes in PCT and PLR. These findings suggest that platelet markers PCT and PLR may be associated with the degree of weight loss.
Conclusion: Our results suggest that platelet markers simply obtained through a complete blood count may be utilized in the treatment and follow-up of obesity, which may lead to a number of different conditions such as coronary artery disease, cerebrovascular events, and myocardial infarction through predisposition to thrombosis.

Anahtar Kelimeler

morbid obesity, plateletcrit, mean platelet volume, body mass index

Kaynakça

• 1.Leitner DR, Frühbeck G, Yumuk V, et al. Obesityand type 2 diabetes:Two diseases with a need forcombined treatment strategies-EASO can lead theway. Obes Facts. 2017; 10: 483-92.
• 2.Rueda- Clausen CF, Ogunleye AA, Sharma AM.Health benefits of long-term weight-lossmaintenance. Annu Rev Nutr. 2015; 35: 475-516
• 3.Flegal KM, Carroll MD, Ogden CL, Johnson CL.Prevalence and trends in obesity among US adults,1999-2000. JAMA. 2002; 288: 1723-7.