Spondylodiscitis and epidural abscess after spinal surgery: case series highlighting diagnostic and therapeutic challenges
Abstract
Objective: To describe the clinical, radiological, microbiological, treatment, and functional characteristics of three patients with postoperative spondylodiscitis (SD) and/or spinal epidural abscess.
Methods: We retrospectively reviewed postoperative SD/EA cases managed at a regional hospital between 2019 and 2023. Patients with previous spinal surgery, magnetic resonance imaging (MRI)-confirmed SD with or without EA, and at least 3 months of follow-up were included. Demographic characteristics, imaging findings, microbiological results, treatment approaches, and clinical outcomes were evaluated.
Results: Three patients (54–67 years) were included. MRI established the diagnosis in all cases by differentiating active infection or epidural abscess from postoperative fibrosis or degenerative changes. Blood cultures identified methicillin-sensitive Staphylococcus aureus in one patient, while urinary and wound cultures yielded organisms in another patient without microbiological confirmation from the spinal infection site. One patient with stable neurological findings improved with antibiotic therapy and multidisciplinary supportive care, whereas two patients underwent surgical decompression, including one with staged hardware revision, in addition to systemic antibiotics. At discharge, two patients achieved assisted ambulation, while one remained non-ambulatory.
Conclusion: Postoperative SD and EA require a high index of suspicion because symptoms may mimic expected postoperative complaints. Contrast-enhanced MRI remains the cornerstone of diagnosis. Early individualized treatment, including appropriate antimicrobial therapy, timely surgical decompression when indicated, and multidisciplinary management, may improve neurological and functional outcomes.
Keywords
Supporting Institution
Ethical Statement
Thanks
References
- 1. Lener S, Hartmann S, Barbagallo GMV, et al. Management of spinal infection: a review of the literature. Acta Neurochir (Wien). 2018;160(3):487-96.
- 2. Tay BK, Deckey J, Hu SS. Spinal infections. J Am Acad Orthop Surg. 2002;10(3):188-97.
- 3. Rotzinger R, Omidi R, Gebhard H, et al. Spondylodiszitis und epiduraler Abszess (Spondylodiscitis and epidural abscesses). Radiologe. 2021;61(3):275-82.
- 4. Zou X, Li X, He K, et al. Current knowledge of vertebral osteomyelitis: a review. Eur J Clin Microbiol Infect Dis. 2025;44(2):213-31.
- 5. Petkova AS, Zhelyazkov CB, Kitov BD. Spontaneous Spondylodiscitis - Epidemiology, Clinical Features, Diagnosis and Treatment. Folia Med (Plovdiv). 2017;59(3):254-60.
- 6. Gentile L, Benazzo F, De Rosa F, et al. A systematic review: characteristics, complications and treatment of spondylodiscitis. Eur Rev Med Pharmacol Sci. 2019;23(2 Suppl):117-28.
- 7. Boody BS, Tarazona DA, Vaccaro AR. Evaluation and Management of Pyogenic and Tubercular Spine Infections. Curr Rev Musculoskelet Med. 2018;11(4):643-52.
- 8. Cheung WY, Luk KD. Pyogenic spondylitis. Int Orthop. 2012;36(2):397-404.
Details
Primary Language
English
Subjects
Brain and Nerve Surgery (Neurosurgery), Pain
Journal Section
Case Report
Publication Date
September 28, 2026
Submission Date
April 17, 2026
Acceptance Date
August 28, 2026
Published in Issue
Year 2026 Volume: 7 Number: 3