In vitro Investigation of Deoxyribonucleic Acid Interaction and Anti-Acetylcholinesterase Activity of Turnip (Brassica Rapa Subsp. Rapa)

Year 2021, Volume: 5 Issue: 1, 50 - 58, 26.06.2021

Alihan Kocabaş , Ayşegül Peksel

Abstract

Turnip (Brassica rapa subsp. Rapa) is a herbaceous and seasonal plant found in the cruciferous family. It is possible to grow in many regions of Europe and West Asia. Although many studies have been carried out to show that turnip juice obtained from turnip root has high biological activity, there has been no previous study on the interaction of turnip root with DNA or its anti-acetylcholinesterase activity. In this study, the interaction and anti-acetylcholinesterase activity of turnip, which obtained three different extracts by applying Soxhlet extraction, were tried to be determined. The DNA binding properties, DNA protective effects, DNA restorative effects and anti-acetylcholinesterase activity of the obtained water, ethanol and ethyl acetate extracts were calculated and the results obtained were compared with other plants of the same species in the past studies.

Keywords

Turnip, DNA, DNA interaction, acetylcholinesterase, Soxhlet extraction, natural product

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