Aim: Jatropha gossypifolia belongs to the family âEuphorbiaceaâ. The coagulant activity and the mechanism of action of Jatropha gossypifolia stem latex as a haemostatic agent were investigated. Methods: The mechanism of action was investigated using doubling dilution technique by mixing neat (undiluted) and serial dilutions of the latex with 30% bovine albumin. Results: The results of whole blood clotting time using Lee and White method and bleeding time using Ivy\'s method were significantly reduced (P < 0.05) when stem latex was introduced than when the tests were performed without stem latex. This means that the stem latex possesses procoagulant activity. Conclusion: The result of this test showed that precipitation of coagulant factors is the mechanism of action of its haemostatic activity. Keywords: Jatropha gossypifolia, haemostatic agent, mechanism.
Oduola, T., Adeosun, G. O., Oduola, T. A., Ovie, G. (2005). Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine, 2(4), 140-143.
AMA
Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. December 2005;2(4):140-143.
Chicago
Oduola, Taofeeq, Ganiyu Oyebola Adeosun, Tesleem Aderemi Oduola, and Godwin Ovie. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2, no. 4 (December 2005): 140-43.
EndNote
Oduola T, Adeosun GO, Oduola TA, Ovie G (December 1, 2005) Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine 2 4 140–143.
IEEE
T. Oduola, G. O. Adeosun, T. A. Oduola, and G. Ovie, “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”, European Journal of General Medicine, vol. 2, no. 4, pp. 140–143, 2005.
ISNAD
Oduola, Taofeeq et al. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2/4 (December 2005), 140-143.
JAMA
Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2:140–143.
MLA
Oduola, Taofeeq et al. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine, vol. 2, no. 4, 2005, pp. 140-3.
Vancouver
Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2(4):140-3.
