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Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent

Year 2005, Volume: 2 Issue: 4, 140 - 143, 01.12.2005

Taofeeq Oduola Ganiyu Oyebola Adeosun Tesleem Aderemi Oduola Godwin Ovie

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Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent

Year 2005, Volume: 2 Issue: 4, 140 - 143, 01.12.2005

Taofeeq Oduola Ganiyu Oyebola Adeosun Tesleem Aderemi Oduola Godwin Ovie

Abstract

Aim: Jatropha gossypifolia belongs to the family “Euphorbiacea”. The coagulant activity and the mechanism of action of Jatropha gossypifolia stem latex as a haemostatic agent were investigated. Methods: The mechanism of action was investigated using doubling dilution technique by mixing neat (undiluted) and serial dilutions of the latex with 30% bovine albumin. Results: The results of whole blood clotting time using Lee and White method and bleeding time using Ivy\'s method were significantly reduced (P < 0.05) when stem latex was introduced than when the tests were performed without stem latex. This means that the stem latex possesses procoagulant activity. Conclusion: The result of this test showed that precipitation of coagulant factors is the mechanism of action of its haemostatic activity. Keywords: Jatropha gossypifolia, haemostatic agent, mechanism.

Keywords

Jatropha gossypifolia haemostatic agent mechanism

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Primary Language English
Journal Section Original Articles
Authors

Taofeeq Oduola This is me

Ganiyu Oyebola Adeosun This is me

Tesleem Aderemi Oduola This is me

Godwin Ovie This is me

Publication Date December 1, 2005
Published in Issue Year 2005 Volume: 2 Issue: 4

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APA Oduola, T., Adeosun, G. O., Oduola, T. A., Ovie, G. (2005). Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine, 2(4), 140-143.
AMA Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. December 2005;2(4):140-143.
Chicago Oduola, Taofeeq, Ganiyu Oyebola Adeosun, Tesleem Aderemi Oduola, and Godwin Ovie. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2, no. 4 (December 2005): 140-43.
EndNote Oduola T, Adeosun GO, Oduola TA, Ovie G (December 1, 2005) Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine 2 4 140–143.
IEEE T. Oduola, G. O. Adeosun, T. A. Oduola, and G. Ovie, “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”, European Journal of General Medicine, vol. 2, no. 4, pp. 140–143, 2005.
ISNAD Oduola, Taofeeq et al. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2/4 (December 2005), 140-143.
JAMA Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2:140–143.
MLA Oduola, Taofeeq et al. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine, vol. 2, no. 4, 2005, pp. 140-3.
Vancouver Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2(4):140-3.