Year 2009,
Volume: 14 Issue: 2, 51 - 56, 14.01.2013
Abstract
Abstract. Antiphospholipid syndrome is characterized by arterial or venous thrombosis and/or recurrent miscarriages together with presence of anticardiolipin antibodies and/or lupus anticoagulant and/or anti-β2-glycoprotein 1 positivity. The exact pathogenic role of antibodies in the development of thrombosis still remains to be fully elucidated. Novel mechanisms involving both the complement pathway and micro-particles have been described. This knowledge might identify novel therapeutic targets and improve the management.
Key words : Antiphospholipid syndrome, Anticardiolipin antibodies, Lupus anticoagulant, anti-β2-glycoprotein 1, Thrombosis, Heparin, Warfarin, Aspirin
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Details
| Primary Language | English |
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| Authors | |
| Publication Date | January 14, 2013 |
| Published in Issue | Year 2009 Volume: 14 Issue: 2 |